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CORDIS

Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis

Rezultaty

Mid-Term recruitment report

MidTerm Recruitment Report M30 Overview of recruitment by study site including numbers recruiting problems and any measures made to compensate if recruitment delays occurred

Consortium Data management plan

Consortium Data Management Plan [M3]

Kick-Off meeting report

Kick-Off meeting report [M1]

Stakeholder engagement plan

Stakeholder Engagement Plan [M12] Regular plan to allow periodical discussion and assessment of DIAMONDS progress.

Annual meeting reports

Annual Meeting Reports [M13, M31, M43, M55] Reports prepared following on from each consortium meeting, focusing on progress on major deliverables and milestones.

EDTL

Establishing a European Diagnostic Transcriptomic Library [M36]. A European library of gene expression data will be created in order to provide data for the molecular taxonomy of infectious and inflammatory diseases, and subsequent generation of the PMSD.

Project website

Project Website [M4] Website will be developed at the earliest stage possible, maintained throughout the duration of the project, in collaboration with WP2.

Publikacje

Febrile illness in high-risk children: a prospective, international observational study

Autorzy: Fabian J. S. van der Velden, Gabriella de Vries, Alexander Martin, Emma Lim, Ulrich von Both, Laura Kolberg, Enitan D. Carrol, Aakash Khanijau, Jethro A. Herberg, Tisham De, Rachel Galassini, Taco W. Kuijpers, Federico Martinón-Torres, Irene Rivero-Calle, Clementien L. Vermont, Nienke N. Hagedoorn, Marko Pokorn, Andrew J. Pollard, Luregn J. Schlapbach, Maria Tsolia, Irini Elefhteriou, Shunmay Yeu
Opublikowane w: European Journal of Pediatrics, 2022, ISSN 0340-6199
Wydawca: Springer Verlag
DOI: 10.1007/s00431-022-04642-1

Biomarkers for Diagnosing Febrile Illness in Immunocompromised Children: A Systematic Review of the Literature

Autorzy: Fabian J. S. van der Velden, Andrew R. Gennery, Marieke Emonts
Opublikowane w: Frontiers in Pediatrics, 2022, ISSN 0891-3668
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.3389/fped.2022.828569

Biobanking and consenting to research: a qualitative thematic analysis of young people’s perspectives in the North East of England

Autorzy: Fabian J. S. van der Velden, Emma Lim, Lily Gills, Jasmin Broadey, Louise Hayes, Eve Roberts, Jack Courtney, Joanne Ball, Jethro Herberg, Rachel Galassini, Marieke Emonts & DIAMONDS consortium
Opublikowane w: BMC Medical Ethics, 2023, ISSN 1472-6939
Wydawca: BioMed Central
DOI: 10.1186/s12910-023-00925-w

Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant

Autorzy: Fabian J. S. van der Velden, Frederik van Delft, Stephen Owens, Judit Llevadias, Michael McKean, Lindsey Pulford, Yusri Taha, Grace Williamson, Quentin Campbell-Hewson, Sophie Hambleton, Rebecca Payne, Christopher Duncan, Catriona Johnston, Jarmila Spegarova, Marieke Emonts
Opublikowane w: Frontiers in Pediatrics, 2022, ISSN 2296-2360
Wydawca: Academic Accelerator
DOI: 10.3389/fped.2022.809061

Adeno-associated virus 2 infection in children with non-A–E hepatitis

Autorzy: Antonia Ho, Richard Orton, Rachel Tayler, Patawee Asamaphan, Vanessa Herder, Chris Davis, Lily Tong, Katherine Smollett, Maria Manali, Jay Allan, Konrad Rawlik, Sarah E. McDonald, Elen Vink, Louisa Pollock, Louise Gannon, Clair Evans, Jim McMenamin, Kirsty Roy, Kimberly Marsh, Titus Divala, Matthew T. G. Holden, Michael Lockhart, David Yirrell, Sandra Currie, Maureen O’Leary, David Henderson, Sa
Opublikowane w: Nature, 2023, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-023-05948-2

Genomic investigations of unexplained acute hepatitis in children

Autorzy: Sofia Morfopoulou, Sarah Buddle, Oscar Enrique Torres Montaguth, Laura Atkinson, José Afonso Guerra-Assunção, Mahdi Moradi Marjaneh, Riccardo Zennezini Chiozzi, Nathaniel Storey, Luis Campos, J. Ciaran Hutchinson, John R. Counsell, Gabriele Pollara, Sunando Roy, Cristina Venturini, Juan F. Antinao Diaz, Ala’a Siam, Luke J. Tappouni, Zeinab Asgarian, Joanne Ng, Killian S. Hanlon, Alexander Len
Opublikowane w: Nature, 2023, ISSN 1476-4687
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-023-06003-w

Group A streptococcal disease in paediatric inpatients:a European perspective

Autorzy: Navin P. Boeddha, Lucy Atkins, Ronald de Groot, Gertjan Driessen, Jan Hazelzet, Werner Zenz, Enitan D. Carrol, Suzanne T. Anderson, Federico Martinon-Torres, Philipp K. A. Agyeman, Rachel Galassini, Jethro Herberg, Michael Levin, Luregn J. Schlapbach, Marieke Emonts & EUCLIDS consortium
Opublikowane w: European Journal of Pediatrics, 2023, ISSN 1432-1076
Wydawca: SpringerLink
DOI: 10.1007/s00431-022-04787-z

External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children

Autorzy: Martin AJ, van der Velden FJS, von Both U on behalf of the PERFORM consortium, et al
Opublikowane w: Archives of Disease in Childhood, 2023, ISSN 0003-9888
Wydawca: BMJ Publishing Group
DOI: 10.1136/archdischild2023-325869

Raising AWaRe-ness of Antimicrobial Stewardship Challenges in Pediatric Emergency Care: Results from the PERFORM Study Assessing Consistency and Appropriateness of Antibiotic Prescribing Across Europe

Autorzy: Laura Kolberg, Aakash Khanijau, Fabian J S van der Velden, Jethro Herberg, Tisham De, Rachel Galassini, Aubrey J Cunnington, Victoria J Wright, Priyen Shah, Myrsini Kaforou, Clare Wilson, Taco Kuijpers, Federico Martinón-Torres, Irene Rivero-Calle, Henriette Moll, Clementien Vermont, Marko Pokorn, Mojca Kolnik, Andrew J Pollard, Philipp K A Agyeman, Luregn J Schlapbach, Maria N Tsolia, Shunmay Ye
Opublikowane w: Clinical Infectious Diseases, 2023, ISSN 1058-4838
Wydawca: University of Chicago Press
DOI: 10.1093/cid/ciad615

Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study

Autorzy: Samuel Channon-Wells; Ortensia Vito, Andrew J McArdle, Eleanor G Seaby, Harsita Patel, Priyen Shah, Ekaterina Pazukhina, Clare Wilson, Claire Broderick, Giselle D'Souza, Ilana Keren, Ruud G Nijman, Adriana Tremoulet, Daniel Munblit, Rolando Ulloa-Gutierrez, Michael J Carter, Padmanabhan Ramnarayan, Tisham De, Clive Hoggart, Elizabeth Whittaker, Jethro A Herberg, Myrsini Kaforou, Aubrey J Cunningto
Opublikowane w: The Lancet Rheumatology, 2023, ISSN 2665-9913
Wydawca: Elsevier
DOI: 10.1016/s2665-9913(23)00029-2

Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature

Autorzy: Heather R Jackson, Luca Miglietta, Dominic Habgood-Coote, Giselle D’Souza, Priyen Shah, Samuel Nichols, Ortensia Vito, Oliver Powell, Maisey Salina Davidson, Chisato Shimizu, Philipp K A Agyeman, Coco R Beudeker, Karen Brengel-Pesce, Enitan D Carrol, Michael J Carter, Tisham De, Irini Eleftheriou, Marieke Emonts, Cristina Epalza, Pantelis Georgiou, Ronald De Groot, Katy Fidler, Colin Fink, Dani
Opublikowane w: Journal of the Pediatric Infectious Diseases Society, 2023, ISSN 2048-7207
Wydawca: University of Chicago Press
DOI: 10.1093/jpids/piad035

Treatment of multisystem inflammatory syndrome in children

Autorzy: Andrew J. McArdle, M.B., B.Chir., Ortensia Vito, M.Sc., Harsita Patel, M.B., B.S., Eleanor G. Seaby, B.M., B.S., Priyen Shah, M.B., B.S., Clare Wilson, M.B., B.Chir., Claire Broderick, M.B., B.S., Ruud Nijman, M.D., Ph.D., Adriana H. Tremoulet, M.D., Daniel Munblit, M.D., Ph.D., Rolando Ulloa-Gutierrez, M.D., Michael J. Carter, B.M., B.Ch., D.Phil., et al.
Opublikowane w: New England Journal of Medicine, 2021, ISSN 0028-4793
Wydawca: Massachusetts Medical Society
DOI: 10.1056/nejmoa2102968

Molecular Pathogen Testing for Identifying the Etiology of Febrile Illness in Immunocompromised Children

Autorzy: Fabian JS van der Velden, Priyen Shah, Marie Voice, Emma Lim, Jethro Herberg, Victoria Wright3, Tisham De, Enitan D. Carrol, Aakash Khanijau, Andrew J Pollard, Stéphane Paulus, Ulrich von Both8, Laura Kolberg, Clementien L Vermont, Nienke N Hagedoorn, Federico Martinón-Torres, Irene Rivero Calle, Philipp KA Agyeman, Luregn J Schlapbach, Maria Tsolia, Irini Eleftheriou, Marko Pokorn, Mojca Kolnik
Opublikowane w: Journal of Biotechnology and Biomedicine, 2023, ISSN 2642-9128
Wydawca: Fortune Journals
DOI: 10.26502/jbb.2642-91280100

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