Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation.

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

NeutroCure newsletter No.3
Set-up of NeutroCure web page/ design of consortium's Logo

Design of consortium’s Logo; set-up of NeutroCure web page that should include consortium’s Logo

NeutroCure newsletter No.2
NeutroCure newsletter No.1

A symposium with participation of the supervisory board

A symposium with participation of the supervisory board (Prof. Dr. C. Hackenberger, Leibniz Research Institute for Molecular Pharmacology and Prof. Dr. R. Voll, University Medical Center Freiburg): report with agenda, list of participants, and executive summary of the meeting.

Setup of in vitro assays to assess ROS production, NET formation and killing of cancerous cells mediated by neutrophils

Publikacje

The Potential of Developing Pan-Coronaviral Antibodies to Spike Peptides in Convalescent COVID-19 Patients.

Autorzy: Andrii Rabets; Galyna Bila; Roman Grytsko; Markian Samborskyy; Yuriy Rebets; Sandor G. Vari; Quentin Pagneux; Alexandre Barras; Rabah Boukherroub; Sabine Szunerits; Rostyslav Bilyy
Opublikowane w: Springer Nature, Numer 2, 2021, ISSN 1661-4917
Wydawca: Springer
DOI: 10.1007/s00005-021-00607-8

3D-Shaped Binders of Unfolded Proteins Inducing Cancer Cell-Specific Endoplasmic Reticulum Stress In Vitro and In Vivo

Autorzy: Insa Klemt, Oleg Varzatskii, Roman Selin, Serhii Vakarov, Vladyslava Kovalska, Galyna Bila, Rostyslav Bilyy, Yan Voloshin, Itziar Cossío Cuartero, Andrés Hidalgo, Benjamin Frey, Ina Becker, Bernhard Friedrich, Rainer Tietze, Ralf P. Friedrich, Christoph Alexiou, Elena-Laura Ursu, Alexandru Rotaru, Iris Solymosi, M. Eugenia Pérez-Ojeda, and Andriy Mokhir
Opublikowane w: Journal of the American Chemical Society, Numer 2, 2023, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.3c08827

Targeted opening of the blood–brain barrier facilitates doxorubicin/anti-PD-1-based chemoimmunotherapy of glioblastoma

Autorzy: Jonathan G. Pol, Manuela Lizarralde-Guerrero, Andrea Checcoli, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 13, 2024, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2024.2385124

Neutrophils as Main Players of Immune Response towards Nondegradable Nanoparticles

Autorzy: Rostyslav Bilyy, Galyna Bila, Oleg Vishchur, Volodymyr Vovk, Martin Herrmann
Opublikowane w: Nanomaterials, Numer 10/7, 2020, Strona(/y) 1273, ISSN 2079-4991
Wydawca: MDPI
DOI: 10.3390/nano10071273

Potent immune-dependent anticancer effects of the non-cardiotoxic anthracycline aclarubicin

Autorzy: Giulia Cerrato, Allan Sauvat, Mahmoud Abdellatif, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 14, 2025, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2025.2515176

Mitochondrial DNA transfer between malignant cells and T lymphocytes shapes the cancer-immunity dialogue

Autorzy: Liwei Zhao, Peng Liu, Oliver Kepp, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 14, 2025, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2025.2512109

Neutrophil Depletion Changes the N-Glycosylation Pattern of IgG in Experimental Murine Sepsis

Autorzy: Kursat O. Yaykasli, Karin A. van Schie, René E. M. Toes, Manfred Wuhrer, Carolien A. M. Koeleman, Galyna Bila, Nazar Negrych, Georg Schett, Jasmin Knopf, Martin Herrmann, Rostyslav Bilyy
Opublikowane w: International Journal of Molecular Sciences, Numer 25, 2025, Strona(/y) 6478, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25126478

Intracellular Amplifiers of Reactive Oxygen Species Affecting Mitochondria as Radiosensitizers

Autorzy: Hong-Gui Xu; Viktor Reshetnikov; Marit Wondrak; Lisa Eckhardt; Leoni A. Kunz-Schughart; Christina Janko; Rainer Tietze; Christoph Alexiou; Hannes Borchardt; Achim Aigner; Wenjie Gong; Michael Schmitt; Leopold Sellner; Steffen Daum; Hülya Gizem Özkan; Andriy Mokhir
Opublikowane w: Cancers, Numer 1, 2022, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14010208

Disruption of cholesterol homeostasis by antidepressants induces immunogenic cell death

Autorzy: Karla Alvarez-Valadez, Jonathan G. Pol, Guido Kroemer, Mojgan Djavaheri-Mergny
Opublikowane w: OncoImmunology, Numer 14, 2025, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2025.2531113

Anticancer Aminoferrocene Derivatives Inducing Production of Mitochondrial Reactive Oxygen Species

Autorzy: Hülya Gizem Özkan; Vanrajsinh Thakor; Hong‐Gui Xu; Galyna Bila; Rostyslav Bilyy; Daria Bida; Martin Böttcher; Dimitrios Mougiakakos; Rainer Tietze; Andriy Mokhir
Opublikowane w: Chemistry, Eur. J., Numer 3, 2022, ISSN 1521-3765
Wydawca: Wiley-VCH GmbH, Weinheim
DOI: 10.1002/chem.202104420

A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity

Autorzy: Sebastian J. Hofer, Ioanna Daskalaki, Mahmoud Abdellatif, Ulrich Stelzl, Simon Sedej, Nektarios Tavernarakis, Guido Kroemer, Frank Madeo
Opublikowane w: Autophagy, Numer 20, 2024, Strona(/y) 2824-2826, ISSN 1554-8627
Wydawca: Landes Bioscience
DOI: 10.1080/15548627.2024.2396793

Neutrophil extracellular traps characterize caseating granulomas

Autorzy: Leticija Zlatar, Jasmin Knopf, Jeeshan Singh, Han Wang, Marco Muñoz-Becerra, Irmgard Herrmann, Rebecca C. Chukwuanukwu, Markus Eckstein, Philip Eichhorn, Ralf J. Rieker, Elisabeth Naschberger, Andreas Burkovski, Veit Krenn, Rostyslav Bilyy, Tetiana Butova, Iryna Liskina, Ihor Kalabukha, Oleg Khmel, Michael Boettcher, Georg Schett, Dmytro Butov, Anton Tkachenko, Martin Herrmann
Opublikowane w: Cell Death & Disease, Numer 15, 2024, ISSN 2041-4889
Wydawca: Nature Publishing Group
DOI: 10.1038/s41419-024-06892-3

An endoplasmic reticulum – specific pro‐amplifier of reactive oxygen species in cancer cells

Autorzy: Hong-Gui Xu, Margot Schikora, Miroslav Sisa, Steffen Daum, Insa Klemt, Christina Janko, Christoph Alexiou, Galyna Bila, Rostyslav Bilyy, Wenjie Gong, Michael Schmitt, Leopold Sellner, Andriy Mokhir
Opublikowane w: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202100054

Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases

Autorzy: Hans-Uwe Simon; Timothée Fettrelet; Aref Hosseini; Darko Stojkov; Shida Yousefi; Rostyslav Bilyy
Opublikowane w: International journal of molecular sciences, Numer 2, 2023, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24032646

Vesicular Messages from Dental Biofilms for Neutrophils

Autorzy: Ljubomir Vitkov, Jelena Krunić, Johanna Dudek, Madhusudhan Reddy Bobbili, Johannes Grillari, Bernhard Hausegger, Irena Mladenović, Nikola Stojanović, Wolf Dietrich Krautgartner, Hannah Oberthaler, Christine Schauer, Martin Herrmann, Jeeshan Singh, Bernd Minnich, Matthias Hannig
Opublikowane w: International Journal of Molecular Sciences, Numer 25, 2025, Strona(/y) 3314, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25063314

Periodontitis-Derived Dark-NETs in Severe Covid-19

Autorzy: Ljubomir Vitkov, Jasmin Knopf, Jelena Krunić, Christine Schauer, Janina Schoen, Bernd Minnich, Matthias Hannig, Martin Herrmann
Opublikowane w: Frontiers in Immunology, 2022, ISSN 1664-3224
Wydawca: Frontiers
DOI: 10.3389/fimmu.2022.872695

Neutralization of acyl CoA binding protein (ACBP) for the experimental treatment of osteoarthritis

Autorzy: Uxía Nogueira-Recalde, Flavia Lambertucci, Léa Montégut, Omar Motiño, Hui Chen, Sylvie Lachkar, Gerasimos Anagnostopoulos, Gautier Stoll, Sijing Li, Vincent Carbonier, Ester Saavedra Díaz, Francisco J. Blanco, Geert van Tetering, Mark de Boer, Maria Chiara Maiuri, Beatriz Caramés, Isabelle Martins, Guido Kroemer
Opublikowane w: Cell Death & Differentiation, Numer 32, 2025, Strona(/y) 1484-1498, ISSN 1350-9047
Wydawca: Nature Publishing Group
DOI: 10.1038/s41418-025-01474-y

Two decades of advances in clinical oncology — lessons learned and future directions

Autorzy: Susana Banerjee, Christopher M. Booth, Eduardo Bruera, Markus W. Büchler, Alexander Drilon, Terry J. Fry, Irene M. Ghobrial, Luca Gianni, Rakesh K. Jain, Guido Kroemer, Josep M. Llovet, Georgina V. Long, Klaus Pantel, Kathy Pritchard-Jones, Howard I. Scher, Josep Tabernero, Ralph R. Weichselbaum, Michael Weller, Yi-Long Wu
Opublikowane w: Nature Reviews Clinical Oncology, Numer 21, 2024, Strona(/y) 771-780, ISSN 1759-4774
Wydawca: Nature Publishing Group
DOI: 10.1038/s41571-024-00945-4

Reaction of N‐Ferrocenylcarbamates with Nitric Oxide: An Application for Detection of Inflammatory Sites In Vivo

Autorzy: Roman Selin, Hülya Gizem Özkan, Galyna Bila, Rostyslav Bilyy, Andriy Mokhir
Opublikowane w: ChemMedChem, Numer 20, 2025, ISSN 1860-7179
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.202500356

Immunogenic oncolysis by tigilanol tiglate

Autorzy: Jonathan G. Pol, Manuela Lizarralde-Guerrero, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 13, 2024, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2024.2360230

Moonlighting chromatin: when DNA escapes nuclear control

Autorzy: Jeeshan Singh, Michael Boettcher, Maximilian Dölling, Annika Heuer, Bettina Hohberger, Moritz Leppkes, Elisabeth Naschberger, Mirco Schapher, Christine Schauer, Janina Schoen, Michael Stürzl, Ljubomir Vitkov, Han Wang, Leticija Zlatar, Georg A. Schett, David S. Pisetsky, Ming-Lin Liu, Martin Herrmann, Jasmin Knopf
Opublikowane w: Cell Death & Differentiation, Numer 30, 2023, Strona(/y) 861-875, ISSN 1350-9047
Wydawca: Nature Publishing Group
DOI: 10.1038/s41418-023-01124-1

A Pleomorphic Puzzle: Heterogeneous Pulmonary Vascular Occlusions in Patients with COVID-19

Autorzy: Jeeshan Singh; Irmgard Herrmann; Aparna Mahajan; Christine Schauer; Xiaomei Shan; Arndt Hartmann; Ralf J. Rieker; Katja Evert; Christina Falkeis; Elisabeth Naschberger; Saskia von Stillfried; Peter Boor; Luis E. Muñoz; Georg Schett; Martin Herrmann; Jasmin Knopf
Opublikowane w: International Journal of Molecular Sciences; Volume 23; Numer 23; Pages: 15126, Numer 2, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232315126

Fatty Acid Metabolism Provides an Essential Survival Signal in OxPhos and BCR DLBCL Cells

Autorzy: Aurélie Montagne, Konstantina Kotta, Karoline Kielbassa-Elkadi, Isabelle Martins, José Ángel Martinez-Climent, Guido Kroemer, Catherine Thieblemont, Véronique Baud
Opublikowane w: Biomedicines, Numer 13, 2025, Strona(/y) 707, ISSN 2227-9059
Wydawca: MDPI AG
DOI: 10.3390/biomedicines13030707

Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex

Autorzy: Simon Lind, Claes Dahlgren, Rikard Holmdahl, Peter Olofsson, Huamei Forsman
Opublikowane w: Journal of Leukocyte Biology, 2020, ISSN 0741-5400
Wydawca: Federation of American Societies for Experimental Biology
DOI: 10.1002/jlb.2hi0520-317r

Neutrophil extracellular traps: from physiology to pathology.

Autorzy: Andrés Hidalgo; Peter Libby; Oliver Soehnlein; Oliver Soehnlein; Iker Valle Aramburu; Venizelos Papayannopoulos; Carlos Silvestre-Roig
Opublikowane w: Cardiovasc Res, Numer 1, 2022, ISSN 1755-3245
Wydawca: Cardiovascular Research
DOI: 10.1093/cvr/cvab329

Metabolic Heterogeneity in Diffuse Large B-Cell Lymphoma Cells Reveals an Innovative Antimetabolic Combination Strategy

Autorzy: Leonardo Lordello, Stéphanie Nuan-Aliman, Karoline Kielbassa-Elkadi, Aurélie Montagne, Konstantina Kotta, Isabelle Martins, Eva Pinto Jurado, Cédric Caradeuc, Jacqueline Lehmann-Che, José Ángel Martínez-Climent, Véronique Meignin, Nicolas Giraud, Guido Kroemer, Gildas Bertho, Catherine Thieblemont, Véronique Baud
Opublikowane w: Cancers, Numer 17, 2025, Strona(/y) 394, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers17030394

A quantitative LC-MS/MS method for analysis of mitochondrial -specific oxysterol metabolism

Autorzy: Khushboo Borah, Olivia J. Rickman, Nikol Voutsina, Isaac Ampong, Dan Gao, Emma L. Baple, Irundika HK. Dias, Andrew H. Crosby, Helen R. Griffiths
Opublikowane w: Redox Biology, Numer 36, 2020, Strona(/y) 101595, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/j.redox.2020.101595

Immunogenic cell death and bystander killing: expanding the therapeutic potential of modern antibody-drug conjugates

Autorzy: Oliver Kepp, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 14, 2025, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2025.2533488

Neutrophil swarm control: what goes up must come down

Autorzy: Uderhardt, Stefan; Knopf, Jasmin; Herrmann, Martin
Opublikowane w: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-2 (2021), Numer 1, 2021, ISSN 2059-3635
Wydawca: Springer Nature
DOI: 10.1038/s41392-021-00836-5

AI-based classification of anticancer drugs reveals nucleolar condensation as a predictor of immunogenicity

Autorzy: Giulia Cerrato, Peng Liu, Liwei Zhao, Adriana Petrazzuolo, Juliette Humeau, Sophie Theresa Schmid, Mahmoud Abdellatif, Allan Sauvat, Guido Kroemer
Opublikowane w: Molecular Cancer, Numer 23, 2024, ISSN 1476-4598
Wydawca: BioMed Central
DOI: 10.1186/s12943-024-02189-3

Obesity accelerates cardiovascular ageing

Autorzy: Celia Ruperez, Frank Madeo, Rafael de Cabo, Guido Kroemer, Mahmoud Abdellatif
Opublikowane w: European Heart Journal, Numer 46, 2025, Strona(/y) 2161-2185, ISSN 0195-668X
Wydawca: Oxford University Press
DOI: 10.1093/eurheartj/ehaf216

Patients with COVID-19: in the dark-NETs of neutrophils

Autorzy: Maximilian Ackermann, Hans-Joachim Anders, Rostyslav Bilyy, Gary L. Bowlin, Christoph Daniel, Rebecca De Lorenzo, Mikala Egeblad, Timo Henneck, Andrés Hidalgo, Markus Hoffmann, Bettina Hohberger, Yogendra Kanthi, Mariana J. Kaplan, Jason S. Knight, Jasmin Knopf, Elzbieta Kolaczkowska, Paul Kubes, Moritz Leppkes, Aparna Mahajan, Angelo A. Manfredi, Christian Maueröder, Norma Maugeri, Ioannis Mitr
Opublikowane w: Nature, 2021, ISSN 1350-9047
Wydawca: Nature Publishing Group
DOI: 10.1038/s41418-021-00805-z

Rapid Generation of Coronaviral Immunity Using Recombinant Peptide Modified Nanodiamonds.

Autorzy: Rostyslav Bilyy; Quentin Pagneux; Nathan François; Galyna Bila; Roman Grytsko; Yuri Lebedin; Alexandre Barras; Jean Dubuisson; Sandrine Belouzard; Karin Séron; Rabah Boukherroub; Sabine Szunerits
Opublikowane w: https://hal.archives-ouvertes.fr/hal-03348197, Numer 1, 2021, ISSN 2076-0817
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens10070861

Hypoxia Promotes Neutrophil Survival After Acute Myocardial Infarction

Autorzy: Maximilian Dölling, Markus Eckstein, Jeeshan Singh, Christine Schauer, Janina Schoen, Xiaomei Shan, Aline Bozec, Jasmin Knopf, Georg Schett, Luis E Muñoz, Martin Herrmann
Opublikowane w: Frontiers in Immunology, 2022, ISSN 1664-3224
Wydawca: Frontiers in Immunology
DOI: 10.3389/fimmu.2022.726153

Matrix-producing neutrophils populate and shield the skin

Autorzy: Tommaso Vicanolo, Alaz Özcan, Jackson LiangYao Li, Carla Huerta-López, Iván Ballesteros, Andrea Rubio-Ponce, Andra C. Dumitru, Jose Ángel Nicolás-Ávila, Miguel Molina-Moreno, Pablo Reyes-Gutierrez, Andrew D. Johnston, Catherine Martone, Eric Greto, Antonio Quílez-Alvarez, Enrique Calvo, Elena Bonzon-Kulichenko, Rebeca Álvarez-Velez, Ming Yao Chooi, Immanuel Kwok, Blanca González-Bermúdez
Opublikowane w: Nature, Numer 641, 2025, Strona(/y) 740-748, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-025-08741-5

Atlas of expression of acyl CoA binding protein/diazepam binding inhibitor (ACBP/DBI) in human and mouse

Autorzy: Sijing Li, Silvia Mingoia, Léa Montégut, Flavia Lambertucci, Hui Chen, Yanbing Dong, Fatima Domenica Elisa De Palma, Sarah Adriana Scuderi, Yan Rong, Vincent Carbonnier, Isabelle Martins, Maria Chiara Maiuri, Guido Kroemer
Opublikowane w: Cell Death & Disease, Numer 16, 2025, ISSN 2041-4889
Wydawca: Nature Publishing Group
DOI: 10.1038/s41419-025-07447-w

Datasets of whole cell and mitochondrial oxysterols derived from THP-1, SH-SY5Y and human peripheral blood mononuclear cells using targeted metabolomics

Autorzy: Khushboo Borah; Olivia J. Rickman; Nikol Voutsina; Emma L. Baple; Irundika H.K. Dias; Andrew H. Crosby; Helen R. Griffiths
Opublikowane w: Data in Brief, Numer 2, 2020, ISSN 2352-3409
Wydawca: Elsevier BV
DOI: 10.1016/j.dib.2020.106382

FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner

Autorzy: Fei He; Apple H.M. Tay; Ahmed Calandigary; Enana Malki; Sayaka Suzuki; Tianjie Liu; Qi Wang; Carlos Fernández-Moro; Marina Kaisso; Peter Olofsson-Sahl; Marit Melssen; Siu Kwan Sze; Mikael Björnstedt; Matthias J. Löhr; Mikael C.I. Karlsson; Rainer Heuchel; Dhifaf Sarhan
Opublikowane w: Cancer Research, Numer 1, 2023, ISSN 0008-5472
Wydawca: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-22-2932

Neutrophils as drivers of vascular injury in sickle cell disease

Autorzy: Lidiane S Torres, Andrés Hidalgo
Opublikowane w: Immunological Reviews, 2022, ISSN 0105-2896
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/imr.13146

ACBP/DBI neutralization for the experimental treatment of fatty liver disease

Autorzy: Omar Motiño, Flavia Lambertucci, Adrien Joseph, Sylvère Durand, Gerasimos Anagnostopoulos, Sijing Li, Vincent Carbonnier, Uxía Nogueira-Recalde, Léa Montégut, Hui Chen, Fanny Aprahamian, Nitharsshini Nirmalathasan, Maria Chiara Maiuri, Federico Pietrocola, Dominique Valla, Cédric Laouénan, Jean-François Gautier, Laurent Castera, null null, Laurent Castera, Anaïs Vallet-Pichard, Tiphaine V
Opublikowane w: Cell Death & Differentiation, Numer 32, 2025, Strona(/y) 434-446, ISSN 1350-9047
Wydawca: Nature Publishing Group
DOI: 10.1038/s41418-024-01410-6

Neutrophil Extracellular Traps Drive Dacryolithiasis

Autorzy: Leticija Zlatar, Thomas Timm, Günter Lochnit, Rostyslav Bilyy, Tobias Bäuerle, Marco Munoz-Becerra, Georg Schett, Jasmin Knopf, Jens Heichel, Mohammad Javed Ali, Mirco Schapher, Friedrich Paulsen, Martin Herrmann
Opublikowane w: Cells, Numer 12, 2025, Strona(/y) 1857, ISSN 2073-4409
Wydawca: MDPI AG
DOI: 10.3390/cells12141857

Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2-complex

Autorzy: Simon Lind; Rikard Holmdahl; Peter Olofsson; Claes Dahlgren; Huamei Forsman
Opublikowane w: Journal of Leukocyte Biology, Numer 4, 2020, ISSN 0741-5400
Wydawca: Federation of American Societies for Experimental Biology
DOI: 10.1101/2020.05.20.106310

Behavioural immune landscapes of inflammation

Autorzy: Georgiana Crainiciuc, Miguel Palomino-Segura, Miguel Molina-Moreno, Jon Sicilia, David G Aragones, Jackson Liang Yao Li, Rodrigo Madurga, José M Adrover, Alejandra Aroca-Crevillén, Sandra Martin-Salamanca, Alfonso Serrano Del Valle, Sandra D Castillo, Heidi C E Welch, Oliver Soehnlein, Mariona Graupera, Fátima Sánchez-Cabo, Alexander Zarbock, Thomas E Smithgall, Mauro Di Pila
Opublikowane w: Nature, 2022, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-021-04263-y

Targeting Lysosomal Thiols for Immunogenic Cancer Cell Death

Autorzy: Anton Arkhypov, Insa Klemt, Galyna Bila, Dina Attia, Svitlana Chernii, Rostyslav Bilyy, Andriy Mokhir
Opublikowane w: Angewandte Chemie, Numer 137, 2025, ISSN 0044-8249
Wydawca: Wiley
DOI: 10.1002/ange.202417509

Acyl CoA binding protein (ACBP): an autophagy checkpoint that can be targeted for improving cancer immunosurveillance

Autorzy: Léa Montégut, Isabelle Martins, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 13, 2024, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2024.2413200

Mitochondria‐Catalyzed Activation of Anticancer Prodrugs

Autorzy: Michael Raucheisen, Dina Attia, Marlies Körber, Alejandra Aroca Crevillén, Andrés Hidalgo, Frank Beierlein, Petra Imhof, Andriy Mokhir
Opublikowane w: ChemCatChem, Numer 17, 2025, ISSN 1867-3880
Wydawca: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202500054

A consensus statement

Autorzy: Daniela F. Quail; Borko Amulic; Monowar Aziz; Betsy J. Barnes; Evgeniy Eruslanov; Zvi G. Fridlender; Helen S. Goodridge; Zvi Granot; Andrés Hidalgo; Anna Huttenlocher; Mariana J. Kaplan; Ilaria Malanchi; Taha Merghoub; Etienne Meylan; Vivek Mittal; Mikael J. Pittet; Andrea Rubio-Ponce; Irina A. Udalova; Timo K. van den Berg; Denisa D. Wagner; Ping Wang; Arturo Zychlinsky; Karin E. de Visser; Mika
Opublikowane w: Journal of Experimental Medicine, Numer 5, 2022, ISSN 0022-1007
Wydawca: Rockefeller University Press
DOI: 10.1084/jem.20220011

Suppression of neutrophils by sodium exacerbates oxidative stress and arthritis

Autorzy: Leticija Zlatar, Aparna Mahajan, Marco Muñoz-Becerra, Daniela Weidner, Galyna Bila, Rostyslav Bilyy, Jens Titze, Markus H. Hoffmann, Georg Schett, Martin Herrmann, Ulrike Steffen, Luis E. Muñoz, Jasmin Knopf
Opublikowane w: Frontiers in Immunology, Numer 14, 2023, ISSN 1664-3224
Wydawca: Frontiers Media SA
DOI: 10.3389/fimmu.2023.1174537

Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity

Autorzy: Stephane Isnard, Tsoarello Mabanga, Léna Royston, Carolina A. Berini, Simeng Bu, Orthy Aiyana, Hansen Feng, Bertrand Lebouché, Cecilia T. Costiniuk, Joseph Cox, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, null null
Opublikowane w: Frontiers in Immunology, Numer 15, 2025, ISSN 1664-3224
Wydawca: Frontiers Media SA
DOI: 10.3389/fimmu.2024.1505752

Anti-DNA-IgM Favors the Detection of NET-Associated Extracellular DNA

Autorzy: Han Wang; Antonia Margarethe Stehr; Jeeshan Singh; Leticija Zlatar; Arndt Hartmann; Katja Evert; Elisabeth Naschberger; Saskia von Stillfried; Peter Boor; Luis E. Muñoz; Jasmin Knopf; Michael Stürzl; Martin Herrmann
Opublikowane w: International Journal of Molecular Sciences, Numer 2, 2023, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24044101

Neutrophils Orchestrate the Periodontal Pocket

Autorzy: Ljubomir Vitkov, Luis E Muñoz, Janina Schoen, Jasmin Knopf, Christine Schauer, Bernd Minnich, Martin Herrmann, Matthias Hannig
Opublikowane w: Frontiers in Immunology, 2021, ISSN 1664-3224
Wydawca: Frontiers
DOI: 10.3389/fimmu.2021.788766

Synthesis of a lysosome-targeting aminoferrocene-based prodrug NCure2

Autorzy: Maximilian Dill, Attia Dina, Mokhir Andriy
Opublikowane w: Arkivoc, Numer 2025, 2025, ISSN 1551-7012
Wydawca: ARKAT USA, Inc.
DOI: 10.24820/ark.5550190.p012.322

Neutrophil Activity and Extracellular Matrix Degradation: Drivers of Lung Tissue Destruction in Fatal COVID-19 Cases and Implications for Long COVID

Autorzy: Teluguakula Narasaraju, Indira Neeli, Sheila L. Criswell, Amita Krishnappa, Wenzhao Meng, Vasuki Silva, Galyna Bila, Volodymyr Vovk, Zolotukhin Serhiy, Gary L. Bowlin, Nuala Meyer, Eline T. Luning Prak, Marko Radic, Rostyslav Bilyy
Opublikowane w: Biomolecules, Numer 14, 2025, Strona(/y) 236, ISSN 2218-273X
Wydawca: MDPI AG
DOI: 10.3390/biom14020236

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Autorzy: Jeeshan Singh, Xiaomei Shan, Aparna Mahajan, Martin Herrmann, Christine Schauer, Jasmin Knopf, Luis E. Muñoz
Opublikowane w: JoVE Journal, 2022, ISSN 2689-3649
Wydawca: JoVE Journal
DOI: 10.3791/63890

Neutrophil Extracellular Traps and DNases Orchestrate Formation of Peritoneal Adhesions

Autorzy: Julia Elrod, Annika Heuer, Jasmin Knopf, Janina Schoen, Lavinia Schönfeld, Magdalena Trochimiuk, Carolin Stiel, Birgit Appl, Laia Pagerols Raluy, Ceren Saygi, Leticija Zlatar, Sami Hosari, Dmytro Royzman, Thomas H. Winkler, Günter Lochnit, Moritz Leppkes, Robert Grützmann, Georg Schett, Christian Tomuschat, Konrad Reinshagen, Martin Herrmann, Tobias A. Fuchs, Michael Boettcher
Opublikowane w: IScience, 2023, ISSN 2589-0042
Wydawca: CellPress
DOI: 10.2139/ssrn.4336831

Metabolic reprogramming promotes apoptosis resistance in acute lymphoblastic leukemia through CASP3 lactylation

Autorzy: Zhi Lin, Fei Long, Jiao Liu, Rui Kang, Daniel J. Klionsky, Guido Kroemer, Daolin Tang, Minghua Yang
Opublikowane w: Molecular Cancer, Numer 24, 2025, ISSN 1476-4598
Wydawca: BioMed Central
DOI: 10.1186/s12943-025-02392-w

RIPK1 inhibition in malignant cells potentiates immunotherapy and radiotherapy outcome

Autorzy: Jonathan G. Pol, Andrea Checcoli, Manuela Lizarralde-Guerrero, Guido Kroemer
Opublikowane w: OncoImmunology, Numer 13, 2024, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2024.2425465

Breaking the Gingival Barrier in Periodontitis

Autorzy: Ljubomir Vitkov; Jeeshan Singh; Christine Schauer; Bernd Minnich; Jelena Krunić; Hannah Oberthaler; Sonja Gamsjaeger; Martin Herrmann; Jasmin Knopf; Matthias Hannig
Opublikowane w: International Journal of Molecular Sciences, Numer 1, 2023, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24054544

A concept of dual-responsive prodrugs based on oligomerization-controlled reactivity of ester groups: an improvement of cancer cells <i>versus</i> neutrophils selectivity of camptothecin

Autorzy: Insa Klemt, Viktor Reshetnikov, Subrata Dutta, Galyna Bila, Rostyslav Bilyy, Itziar Cossío Cuartero, Andrés Hidalgo, Adrian Wünsche, Maximilian Böhm, Marit Wondrak, Leoni A. Kunz-Schughart, Rainer Tietze, Frank Beierlein, Petra Imhof, Sabrina Gensberger-Reigl, Monika Pischetsrieder, Marlies Körber, Tina Jost, Andriy Mokhir
Opublikowane w: RSC Medicinal Chemistry, Numer 15, 2024, Strona(/y) 1189-1197, ISSN 2632-8682
Wydawca: Royal Society of Chemistry (RSC)
DOI: 10.1039/d3md00609c

Rapid Generation of Coronaviral Immunity Using Recombinant Peptide Modified Nanodiamonds

Autorzy: Rostyslav Bilyy, Quentin Pagneux, Nathan François, Galyna Bila, Roman Grytsko, Yuri Lebedin, Alexandre Barras, Jean Dubuisson, Sandrine Belouzard, Karin Séron, Rabah Boukherroub, Sabine Szunerits
Opublikowane w: Pathogens, Numer 10, 2025, Strona(/y) 861, ISSN 2076-0817
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens10070861

Clinically relevant GABARAP deficiency abrogates bortezomib-induced immunogenic cell death in multiple myeloma

Autorzy: Liwei Zhao, Zhe Shen, Guido Kroemer, Oliver Kepp
Opublikowane w: OncoImmunology, Numer 13, 2024, ISSN 2162-402X
Wydawca: Informa UK Limited
DOI: 10.1080/2162402x.2024.2360275

Correction: Bilyy et al. Rapid Generation of Coronaviral Immunity Using Recombinant Peptide Modified Nanodiamonds. Pathogens 2021, 10, 861

Autorzy: Rostyslav Bilyy, Quentin Pagneux, Nathan François, Galyna Bila, Roman Grytsko, Yuri Lebedin, Alexandre Barras, Jean Dubuisson, Sandrine Belouzard, Karin Séron, Rabah Boukherroub, Sabine Szunerits
Opublikowane w: Pathogens, Numer 12, 2023, Strona(/y) 1411, ISSN 2076-0817
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens12121411

Neutrophils' Extracellular Trap Mechanisms: From Physiology to Pathology

Autorzy: Janina Schoen, Maximilien Euler, Christine Schauer, Georg Schett, Martin Herrmann, Jasmin Knopf, Kursat Oguz Yaykasli
Opublikowane w: MDPI, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232112855

Calpain-1 weakens the nuclear envelope and promotes the release of neutrophil extracellular traps

Autorzy: Jeeshan Singh, Leticija Zlatar, Marco Muñoz-Becerra, Günter Lochnit, Irmgard Herrmann, Felix Pfister, Christina Janko, Jasmin Knopf, Moritz Leppkes, Janina Schoen, Luis E. Muñoz, Georg Schett, Martin Herrmann, Christine Schauer, Aparna Mahajan
Opublikowane w: Cell Communication and Signaling, Numer 22, 2024, ISSN 1478-811X
Wydawca: BioMed Central
DOI: 10.1186/s12964-024-01785-6

Formation and Clearance of NETs in Health and Disease

Autorzy: Jasmin Knopf, Aparna Mahajan, Luis E. Muñoz, Martin Herrmann
Opublikowane w: Cells, Numer 11, 2025, Strona(/y) 4022, ISSN 2073-4409
Wydawca: MDPI AG
DOI: 10.3390/cells11244022

Neutrophil NADPH oxidase promotes bacterial eradication and regulates NF-κB-Mediated inflammation via NRF2 signaling during urinary tract infections

Autorzy: Israel Cotzomi-Ortega, Emily E. Rosowski, Xin Wang, Yuriko I. Sanchez-Zamora, Jeimy M. Lopez-Torres, Gamaliel Sanchez-Orellana, Rachel Han, Gabriela Vásquez-Martínez, Gabriel Mayoral Andrade, Gregory Ballash, Hanna Cortado, Birong Li, Yusuf Ali, Raul Rascon, Frank Robledo-Avila, Santiago Partida-Sanchez, Eduardo Pérez-Campos, Peter Olofsson-Sahl, Diana Zepeda-Orozco, John David Spencer, Brian B
Opublikowane w: Mucosal Immunology, Numer 18, 2025, Strona(/y) 402-417, ISSN 1933-0219
Wydawca: Nature Publishing Group
DOI: 10.1016/j.mucimm.2024.12.010

NET Formation in Systemic Lupus Erythematosus: Changes during the COVID-19 Pandemic

Autorzy: Jasmin Knopf, Johanna Sjöwall, Martina Frodlund, Jorma Hinkula, Martin Herrmann, Christopher Sjöwall
Opublikowane w: MDPI, 2022, ISSN 2073-4409
Wydawca: MDPI
DOI: 10.3390/cells11172619

Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes

Autorzy: Stephan Culemann; Katharina Knab; Maximilien Euler; Anja Wegner; Hilal Garibagaoglu; Jochen Ackermann; Kim Fischer; Deborah Kienhöfer; Georgiana Crainiciuc; Jonas Hahn; Anika Grüneboom; Falk Nimmerjahn; Stefan Uderhardt; Andrés Hidalgo; Georg Schett; Markus H. Hoffmann; Gerhard Krönke
Opublikowane w: Journal of Experimental Medicine, Numer 4, 2023, ISSN 0022-1007
Wydawca: Rockefeller University Press
DOI: 10.1084/jem.20220525

Neutrophils in Physiology and Pathology

Autorzy: Alejandra Aroca-Crevillén, Tommaso Vicanolo, Samuel Ovadia, Andrés Hidalgo
Opublikowane w: Annual Review of Pathology: Mechanisms of Disease, Numer 19, 2024, Strona(/y) 227-259, ISSN 1553-4006
Wydawca: Annual Reviews, Inc.
DOI: 10.1146/annurev-pathmechdis-051222-015009

Nano- and Microparticles and Their Role in Inflammation and Immune Response: Focus on Neutrophil Extracellular Traps

Autorzy: Galyna Bila, Andrii Rabets, Rostyslav Bilyy
Opublikowane w: Biomedical Nanomaterials, 2021, Strona(/y) 149-170, ISBN 978-3-030-76234-6
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-030-76235-3_6

Aminoferrocene- or ferrocenylaniline-based ROS amplifiers with anticancer activity

Autorzy: Honggui Xu
Opublikowane w: 2022
Wydawca: FAU

Wyszukiwanie danych OpenAIRE...

Rezultaty

Publikacje

Udostępnij tę stronę Udostępnij tę stronę w mediach społecznościowych

Pobierz Pobierz zawartość strony