Macro-Nanomedicine to Treat Metastatic Cancer

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Nanoparticle Diagnostics and Theranostics in the Clinic

Autorzy: Roger M. Pallares, Felix M. Mottaghy, Volkmar Schulz, Fabian Kiessling, Twan Lammers
Opublikowane w: Journal of Nuclear Medicine, Numer 63, 2023, Strona(/y) 1802-1808, ISSN 0161-5505
Wydawca: Kexue Chubaneshe/Science Press
DOI: 10.2967/jnumed.122.263895

CCL2 chemokine inhibition primes the tumor vasculature for improved nanomedicine delivery and efficacy

Autorzy: Diana Möckel, Matthias Bartneck, Patricia Niemietz, Maike Wagner, Josef Ehling, Elena Rama, Marek Weiler, Felix Gremse, Dirk Eulberg, Robert Pola, Michal Pechar, Tomas Etrych, Gert Storm, Fabian Kiessling, Frank Tacke, Twan Lammers
Opublikowane w: Journal of Controlled Release, Numer 365, 2024, Strona(/y) 358-368, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2023.11.044

Hybrid ultrasound and photoacoustic contrast agent designs combining metal phthalocyanines and PBCA microbubbles

Autorzy: Roman A. Barmin, MirJavad Moosavifar, Rui Zhang, Stephan Rütten, Sven Thoröe-Boveleth, Elena Rama, Tarun Ojha, Fabian Kiessling, Twan Lammers, Roger M. Pallares
Opublikowane w: Journal of Materials Chemistry B, Numer 12, 2024, Strona(/y) 2511-2522, ISSN 2050-7518
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3tb02950f

Nonspherical ultrasound microbubbles

Autorzy: Anshuman Dasgupta, Tao Sun, Roberto Palomba, Elena Rama, Yong-Zhi Zhang, Chanikarn Power, Diana Moeckel, Mengjiao Liu, Apoorva Sarode, Marek Weiler, Alessandro Motta, Céline Porte, Zuzanna Magnuska, Asmaa Said ElShafei, Roman Barmin, Adam Graham, Arthur McClelland, Dirk Rommel, Elmar Stickeler, Fabian Kiessling, Roger M. Pallares, Laura De Laporte, Paolo Decuzzi, Nathan McDannold, Samir Mitrago
Opublikowane w: Proceedings of the National Academy of Sciences of the United States of America, 2023, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2218847120

Profiling target engagement and cellular uptake of cRGD-decorated clinical-stage core-crosslinked polymeric micelles

Autorzy: Federica De Lorenzi, Larissa Yokota Rizzo, Rasika Daware, Alessandro Motta, Maike Baues, Matthias Bartneck, Michael Vogt, Marc van Zandvoort, Leonard Kaps, Qizhi Hu, Marielle Thewissen, Luca Casettari, Cristianne J. F. Rijcken, Fabian Kiessling, Alexandros Marios Sofias, Twan Lammers
Opublikowane w: Drug Delivery and Translational Research, Numer 13, 2023, Strona(/y) 1195-1211, ISSN 2190-393X
Wydawca: Springer Pub. Co.,
DOI: 10.1007/s13346-022-01204-8

A randomized controlled clinical trial

Autorzy: Metselaar, Josbert M.; Middelink, Leonie M.; Wortel, Cornelis H.; Bos, Reinhard; van Laar, Jacob M.; Vonkeman, Harald E.; Westhovens, Rene; Lammers, Twan; Yao, Siu Long; Kothekar, Mudgal; Raut, Atul; Bijlsma, Johannes W.J.
Opublikowane w: VOLUME=341;STARTPAGE=548;ENDPAGE=554;ISSN=0168-3659;TITLE=Journal of controlled release, Numer 1, 2023, ISSN 0168-3659
Wydawca: Elsevier BV

Nanoparticle delivery to tumours: from EPR and ATR mechanisms to clinical impact

Autorzy: Anshuman Dasgupta, Alexandros Marios Sofias, Fabian Kiessling, Twan Lammers
Opublikowane w: Nature Reviews Bioengineering, Numer 2, 2024, Strona(/y) 714-716, ISSN 2731-6092
Wydawca: Springer-Nature
DOI: 10.1038/s44222-024-00203-3

Iron metabolism: pathophysiology and pharmacology

Autorzy: Karolin Roemhild, Finn von Maltzahn, Ralf Weiskirchen, Ruth Knüchel, Saskia von Stillfried, Twan Lammers
Opublikowane w: Trends in Pharmacological Sciences, Numer 42/8, 2021, Strona(/y) 640-656, ISSN 0165-6147
Wydawca: Elsevier BV
DOI: 10.1016/j.tips.2021.05.001

Lyophilization stabilizes clinical‐stage core‐crosslinked polymeric micelles to overcome cold chain supply challenges

Autorzy: Tarun Ojha, Qizhi Hu, Claudio Colombo, Jan Wit, Michiel Geijn, Mies J. Steenbergen, Mahsa Bagheri, Hiltrud Königs‐Werner, Eva Miriam Buhl, Ruchi Bansal, Yang Shi, Wim E. Hennink, Gert Storm, Cristianne J. F. Rijcken, Twan Lammers
Opublikowane w: Biotechnology Journal, Numer 16/6, 2021, Strona(/y) 2000212, ISSN 1860-6768
Wydawca: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.202000212

Effect of Radical Polymerization Method on Pharmaceutical Properties of Π Electron-Stabilized HPMA-Based Polymeric Micelles

Autorzy: Armin Azadkhah Shalmani; Zaheer Ahmed; Maryam Sheybanifard; Alec Wang; Marek Weiler; Eva Miriam Buhl; Geir Klinkenberg; Ruth Schmid; Wim Hennink; Fabian Kiessling; Josbert M. Metselaar; Twan Lammers; Quim Peña; Yang Shi
Opublikowane w: Biomacromolecules, Numer 1, 2023, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.2c01261

Mechanisms and Barriers in Nanomedicine: Progress in the Field and Future Directions

Autorzy: Thomas Anchordoquy, Natalie Artzi, Irina V. Balyasnikova, Yechezkel Barenholz, Ninh M. La-Beck, Jacob S. Brenner, Warren C. W. Chan, Paolo Decuzzi, Agata A. Exner, Alberto Gabizon, Biana Godin, Samuel K. Lai, Twan Lammers, Michael J. Mitchell, S. Moein Moghimi, Vladimir R. Muzykantov, Dan Peer, Juliane Nguyen, Rachela Popovtzer, Madison Ricco, Natalie J. Serkova, Ravi Singh, Avi Schroeder, Anna A.
Opublikowane w: ACS Nano, Numer 18, 2024, Strona(/y) 13983-13999, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.4c00182

Liposome manufacturing under continuous flow conditions: towards a fully integrated set-up with in-line control of critical quality attributes

Autorzy: Maryam Sheybanifard; Luis P. B. Guerzoni; Abdolrahman Omidinia-Anarkoli; Laura De Laporte; Johannes Buyel; Rut Besseling; Michiel Damen; Ad Gerich; Twan Lammers; Josbert M. Metselaar
Opublikowane w: Lab on a Chip, Numer 1, 2022, ISSN 1473-0197
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2lc00463a

Polymeric materials for ultrasound imaging and therapy

Autorzy: Roman A. Barmin, MirJavad Moosavifar, Anshuman Dasgupta, Andreas Herrmann, Fabian Kiessling, Roger M. Pallares, Twan Lammers
Opublikowane w: Chemical Science, Numer 14, 2024, Strona(/y) 11941-11954, ISSN 2041-6520
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3sc04339h

Transferrin Receptor‐Targeted Nonspherical Microbubbles for Blood–Brain Barrier Sonopermeation

Autorzy: Anshuman Dasgupta, Tao Sun, Elena Rama, Alessandro Motta, Yongzhi Zhang, Chanikarn Power, Diana Moeckel, Stecia‐Marie Fletcher, Mirjavad Moosavifar, Roman Barmin, Céline Porte, Eva Miriam Buhl, Céline Bastard, Roger M. Pallares, Fabian Kiessling, Nathan McDannold, Samir Mitragotri, Twan Lammers
Opublikowane w: Advanced Materials, Numer 35, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202308150

A randomized controlled clinical trial

Autorzy: Metselaar, Josbert M.; Middelink, Leonie M.; Wortel, Cornelis H.; Bos, Reinhard; van Laar, Jacob M.; Vonkeman, Harald E.; Westhovens, Rene; Lammers, Twan; Yao, Siu Long; Kothekar, Mudgal; Raut, Atul; Bijlsma, Johannes W.J.
Opublikowane w: Journal of Controlled Release, Numer 1, 2022, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2021.12.007

Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes

Autorzy: Jeffrey Momoh; Dimitrios Kapsokalyvas; Michael Vogt; Sjoerd Hak; Fabian Kiessling; Marc van Zandvoort; Twan Lammers; Alexandros Marios Sofias
Opublikowane w: Advanced Drug Delivery Reviews, Numer 1, 2022, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2022.114528

Strategies to Maximize Anthracycline Drug Loading in Albumin Microbubbles

Autorzy: Mengjiao Liu; Anshuman Dasgupta; Na Qu; Elena Rama; Fabian Kiessling; Twan Lammers
Opublikowane w: ACS Biomaterials Science Engineering, Numer 2, 2022, ISSN 2373-9878
Wydawca: ACS
DOI: 10.1021/acsbiomaterials.1c01203

Nanomedicine Tumor Targeting

Autorzy: Twan Lammers
Opublikowane w: Advanced Materials, Numer 36, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202312169

Towards bypassing EPR

Autorzy: Mohamadreza Amin; Twan Lammers; Timo L.M. ten Hagen
Opublikowane w: Advanced Drug Delivery Reviews, Numer 1, 2022, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2022.114503

Dexamethasone nanomedicines for COVID-19

Autorzy: Twan Lammers, Alexandros Marios Sofias, Roy van der Meel, Raymond Schiffelers, Gert Storm, Frank Tacke, Steffen Koschmieder, Tim H. Brümmendorf, Fabian Kiessling, Josbert M. Metselaar
Opublikowane w: Nature Nanotechnology, Numer 15, 2021, Strona(/y) 622-624, ISSN 1748-3387
Wydawca: Nature Publishing Group
DOI: 10.1038/s41565-020-0752-z

Nanoscale engineering of gold nanostars for enhanced photoacoustic imaging

Autorzy: Rui Zhang, Sven Thoröe-Boveleth, Dmitry N. Chigrin, Fabian Kiessling, Twan Lammers, Roger M. Pallares
Opublikowane w: Journal of Nanobiotechnology, Numer 22, 2024, ISSN 1477-3155
Wydawca: BioMed Central
DOI: 10.1186/s12951-024-02379-7

Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles

Autorzy: Ilaria Biancacci, Qingxue Sun, Diana Möckel, Felix Gremse, Stefanie Rosenhain, Fabian Kiessling, Matthias Bartneck, Qizhi Hu, Marielle Thewissen, Gert Storm, Wim E. Hennink, Yang Shi, Cristianne J.F. Rijcken, Twan Lammers, Alexandros Marios Sofias
Opublikowane w: Journal of Controlled Release, Numer 328, 2020, Strona(/y) 805-816, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2020.09.046

Clinical translation and landscape of silver nanoparticles

Autorzy: Manuel Dias, Rui Zhang, Twan Lammers, Roger M. Pallares
Opublikowane w: Drug Delivery and Translational Research, Numer 15, 2025, Strona(/y) 789-797, ISSN 2190-393X
Wydawca: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01716-5

Enhanced Stable Cavitation and Nonlinear Acoustic Properties of Poly(butyl cyanoacrylate) Polymeric Microbubbles after Bioconjugation

Autorzy: Roman A. Barmin; Anshuman Dasgupta; Anne Rix; Marek Weiler; Lia Appold; Stephan Rütten; Frederic Padilla; Alexander J. C. Kuehne; Andrij Pich; Laura De Laporte; Fabian Kiessling; Roger M. Pallares; Twan Lammers
Opublikowane w: ACS Biomaterials Science Engineering, Numer 1, 2023, ISSN 2373-9878
Wydawca: ACS
DOI: 10.1021/acsbiomaterials.2c01021

Π electron-stabilized polymeric micelles potentiate docetaxel therapy in advanced-stage gastrointestinal cancer

Autorzy: Chenghua Liang, Xiangyang Bai, Cuiling Qi, Qingxue Sun, Xiaoyan Han, Tianyun Lan, Haibo Zhang, Xiaoming Zheng, Rongpu Liang, Ju Jiao, Zongheng Zheng, Jiafeng Fang, Purun Lei, Yan Wang, Diana Möckel, Josbert M. Metselaar, Gert Storm, Wim E. Hennink, Fabian Kiessling, Hongbo Wei, Twan Lammers, Yang Shi, Bo Wei
Opublikowane w: Biomaterials, Numer 266, 2021, Strona(/y) 120432, ISSN 0142-9612
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120432

Cancer nanomedicine meets immunotherapy: opportunities and challenges

Autorzy: Qingxue Sun, Xiangyang Bai, Alexandros Marios Sofias, Roy van der Meel, Eduardo Ruiz-Hernandez, Gert Storm, Wim E. Hennink, Bruno De Geest, Fabian Kiessling, Hai-jun Yu, Twan Lammers, Yang Shi
Opublikowane w: Acta Pharmacologica Sinica, Numer 41/7, 2020, Strona(/y) 954-958, ISSN 1671-4083
Wydawca: Shanghai Institute of Materia Medica
DOI: 10.1038/s41401-020-0448-9

Desmoplastic tumor priming using clinical-stage corticosteroid liposomes

Autorzy: Tarun Ojha, Gideon J.L. Schaefer, Rahaf Mihyar, Vertika Pathak, Josef Ehling, Elena Rama, Federica De Lorenzi, Asmaa Said Elshafei, Diana Moeckel, Sara Elsafy, Benjamin Theek, Maike Wagner, Paolo Ceccarini, Lorena Consolino, Marek Weiler, Fabian Peisker, Tim Caspers, Quim Peña, Roman Barmin, Felix Gremse, Robert Pola, Michal Pechar, Tomáš Etrych, Steffen Meurer, Ralf Weiskirchen, Rafael Kramann
Opublikowane w: Cell Biomaterials, Numer 1-16, 2025, Strona(/y) 100051, ISSN 3050-5623
Wydawca: Elsevier BV
DOI: 10.1016/j.celbio.2025.100051

Improving Lyophilization and Long-Term Stability of Gold Nanostars for Photothermal Applications

Autorzy: Zhongqian Xi, Rui Zhang, Sven Thoröe-Boveleth, Fabian Kiessling, Twan Lammers, Roger M. Pallares
Opublikowane w: ACS Applied Nano Materials, Numer 6, 2023, Strona(/y) 17336-17346, ISSN 2574-0970
Wydawca: ACS
DOI: 10.1021/acsanm.3c03953

Histopathological biomarkers for predicting the tumour accumulation of nanomedicines

Autorzy: Jan-Niklas May, Jennifer I. Moss, Florian Mueller, Susanne K. Golombek, Ilaria Biancacci, Larissa Rizzo, Asmaa Said Elshafei, Felix Gremse, Robert Pola, Michal Pechar, Tomáš Etrych, Svea Becker, Christian Trautwein, Roman D. Bülow, Peter Boor, Ruth Knuechel, Saskia von Stillfried, Gert Storm, Sanyogitta Puri, Simon T. Barry, Volkmar Schulz, Fabian Kiessling, Marianne B. Ashford, Twan Lammers
Opublikowane w: Nature Biomedical Engineering, 2024, ISSN 2157-846X
Wydawca: Springer-Nature
DOI: 10.1038/s41551-024-01197-4

Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles

Autorzy: Bi Wang, Simon Van Herck, Yong Chen, Xiangyang Bai, Zifu Zhong, Kim Deswarte, Bart N. Lambrecht, Niek N. Sanders, Stefan Lienenklaus, Hans W. Scheeren, Sunil A. David, Fabian Kiessling, Twan Lammers, Bruno G. De Geest, Yang Shi
Opublikowane w: Journal of the American Chemical Society, Numer 142/28, 2020, Strona(/y) 12133-12139, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.0c01928

Targeting intracellular and extracellular receptors with nano-to-macroscale biomaterials to activate immune cells

Autorzy: Bi Wang, Hao Cui, Fabian Kiessling, Twan Lammers, Dirk Baumjohann, Yang Shi
Opublikowane w: Journal of Controlled Release, Numer 357, 2024, Strona(/y) 52-66, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2023.03.028

A phase I first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone in patients with progressive multiple myeloma

Autorzy: Josbert Metselaar, Twan Lammers, Amelie Boquoi, Roland Fenk, Fabio Testaquadra, Mirle Schemionek, Fabian Kiessling, Susanne Isfort, Stefan Wilop, Martina Crysandt
Opublikowane w: Drug Delivery and Translational Research, Numer 13, 2023, Strona(/y) 915-923, ISSN 2190-393X
Wydawca: Springer Pub. Co.,
DOI: 10.1007/s13346-022-01268-6

Clinical translation of quantum dots

Autorzy: Roger M Pallares, Fabian Kiessling, Twan Lammers
Opublikowane w: Nanomedicine, Numer 19, 2024, Strona(/y) 2433-2435, ISSN 1743-5889
Wydawca: Future Medicine Ltd.
DOI: 10.1080/17435889.2024.2405458

Lipids in disease pathology, diagnosis & therapy.

Autorzy: Twan Lammers; Heidi Noels
Opublikowane w: Advanced Drug Delivery Reviews, Numer 1, 2020, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2020.11.006

Cancer-associated fibroblasts: Origin, function, imaging, and therapeutic targeting

Autorzy: Rahul Rimal, Prachi Desai, Rasika Daware, Aisa Hosseinnejad, Jai Prakash, Twan Lammers, Smriti Singh
Opublikowane w: Advanced Drug Delivery Reviews, Numer 189, 2023, Strona(/y) 114504, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2022.114504

A paradigm shift in cancer nanomedicine: from traditional tumor targeting to leveraging the immune system

Autorzy: Alexandros Marios Sofias, Francis Combes, Steffen Koschmieder, Gert Storm, Twan Lammers
Opublikowane w: Drug Discovery Today, Numer 26/6, 2021, Strona(/y) 1482-1489, ISSN 1359-6446
Wydawca: Elsevier BV
DOI: 10.1016/j.drudis.2021.02.017

Multidrug micelles and sonopermeation for chemotherapy co-delivery to brain tumors

Autorzy: Anshuman Dasgupta, Jan-Niklas May, Geir Klinkenberg, Helena C. Besse, Eva Miriam Buhl, Diana Moeckel, Rahaf Mihyar, Quim Peña, Armin Azadkhah Shalmani, Christopher Hark, Anne Rix, Susanne Koletnik, Josbert Metselaar, Yang Shi, Wim E. Hennink, Gert Storm, Dannis van Vuurden, Chrit Moonen, Mario Ries, Ruth Schmid, Fabian Kiessling, Twan Lammers
Opublikowane w: Journal of Controlled Release, Numer 380, 2025, Strona(/y) 818-828, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2025.02.018

Clinical translation of gold nanoparticles

Autorzy: Rui Zhang; Fabian Kiessling; Twan Lammers; Roger M. Pallares
Opublikowane w: Drug Delivery and Translational Research, Numer 1, 2022, ISSN 2190-393X
Wydawca: Springer Pub. Co.,
DOI: 10.18154/rwth-2022-08962

Drug Loading in Poly(butyl cyanoacrylate)-Based Polymeric Microbubbles

Autorzy: Mengjiao Liu, Anshuman Dasgupta, Patrick Koczera, Sandra Schipper, Dirk Rommel, Yang Shi, Fabian Kiessling, Twan Lammers
Opublikowane w: Molecular Pharmaceutics, Numer 17/8, 2020, Strona(/y) 2840-2848, ISSN 1543-8384
Wydawca: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.0c00242

Effect of Cellular and Microenvironmental Multidrug Resistance on Tumor-Targeted Drug Delivery in Triple-Negative Breast Cancer

Autorzy: Okan Tezcan, Asmaa Said Elshafei, Karina Benderski, Elena Rama, Maike Wagner, Diana Moeckel, Robert Pola, Michal Pechar, Tomas Etrych, Saskia von Stillfried, Fabian Kiessling, Ralf Weiskirchen, Steffen Meurer, Twan Lammers
Opublikowane w: Journal of Controlled Release, 2023, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2022.12.056

Biomedical Metal–Organic Framework Materials: Perspectives and Challenges

Autorzy: Alec Wang, Madeline Walden, Romy Ettlinger, Fabian Kiessling, Jeremiah J. Gassensmith, Twan Lammers, Stefan Wuttke, Quim Peña
Opublikowane w: Advanced Functional Materials, 2023, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202308589

Multidrug nanomedicine

Autorzy: Alexandros Marios Sofias, Twan Lammers
Opublikowane w: Nature Nanotechnology, Numer 18, 2023, Strona(/y) 104-106, ISSN 1748-3387
Wydawca: Nature Publishing Group
DOI: 10.1038/s41565-022-01265-3

Tunable polymeric micelles for taxane and corticosteroid co-delivery

Autorzy: Armin Azadkhah Shalmani, Alec Wang, Zaheer Ahmed, Maryam Sheybanifard, Rahaf Mihyar, Eva Miriam Buhl, Michael Pohl, Wim E. Hennink, Fabian Kiessling, Josbert M. Metselaar, Yang Shi, Twan Lammers, Quim Peña
Opublikowane w: Drug Delivery and Translational Research, Numer 14, 2024, Strona(/y) 2642-2654, ISSN 2190-393X
Wydawca: Springer Pub. Co.,
DOI: 10.1007/s13346-023-01465-x

Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix

Autorzy: Federica De Lorenzi, Nadja Hansen, Benjamin Theek, Rasika Daware, Alessandro Motta, Saskia Breuel, Ramin Nasehi, Julian Baumeister, Jan Schöneberg, Natalija Stojanović, Saskia von Stillfried, Michael Vogt, Gerhard Müller‐Newen, Jochen Maurer, Alexandros Marios Sofias, Twan Lammers, Horst Fischer, Fabian Kiessling
Opublikowane w: Advanced Materials, Numer 36, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202303196

Polymeric Microbubble Shell Engineering: Microporosity as a Key Factor to Enhance Ultrasound Imaging and Drug Delivery Performance

Autorzy: Mirjavad Moosavifar, Roman A. Barmin, Elena Rama, Anne Rix, Rustam A. Gumerov, Thomas Lisson, Céline Bastard, Stephan Rütten, Noah Avraham‐Radermacher, Jens Koehler, Michael Pohl, Vedangi Kulkarni, Jasmin Baier, Susanne Koletnik, Rui Zhang, Anshuman Dasgupta, Alessandro Motta, Marek Weiler, Igor I. Potemkin, Georg Schmitz, Fabian Kiessling, Twan Lammers, Roger M. Pallares
Opublikowane w: Advanced Science, Numer 11, 2024, Strona(/y) 1-13, ISSN 2198-3844
Wydawca: Wiley
DOI: 10.1002/advs.202404385

Cancer nanomedicine

Autorzy: Sangeeta N. Bhatia, Xiaoyuan Chen, Marina A. Dobrovolskaia, Twan Lammers
Opublikowane w: Nature Reviews Cancer, 2022, ISSN 1474-175X
Wydawca: Nature Publishing Group
DOI: 10.1038/s41568-022-00496-9

A translational framework to DELIVER nanomedicines to the clinic

Autorzy: Paul Joyce, Christine J. Allen, María José Alonso, Marianne Ashford, Michelle S. Bradbury, Matthieu Germain, Maria Kavallaris, Robert Langer, Twan Lammers, Maria Teresa Peracchia, Amirali Popat, Clive A. Prestidge, Cristianne J. F. Rijcken, Bruno Sarmento, Ruth B. Schmid, Avi Schroeder, Santhni Subramaniam, Chelsea R. Thorn, Kathryn A. Whitehead, Chun-Xia Zhao, Hélder A. Santos
Opublikowane w: Nature Nanotechnology, Numer 19, 2024, Strona(/y) 1597-1611, ISSN 1748-3387
Wydawca: Nature Publishing Group
DOI: 10.1038/s41565-024-01754-7

Intermittent Fasting Primes the Tumor Microenvironment and Improves Nanomedicine Delivery in Hepatocellular Carcinoma

Autorzy: Svea Becker, Jeffrey Momoh, Ilaria Biancacci, Diana Möckel, Qingbi Wang, Jan‐Niklas May, Huan Su, Lena Susanna Candels, Marie‐Luise Berres, Fabian Kiessling, Maximilian Hatting, Twan Lammers, Christian Trautwein
Opublikowane w: Small, Numer 19, 2024, ISSN 1613-6810
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202208042

Engineering the Acoustic Response and Drug Loading Capacity of PBCA-Based Polymeric Microbubbles with Surfactants

Autorzy: Roman A. Barmin; Anshuman Dasgupta; Céline Bastard; Laura De Laporte; Stephan Rütten; Marek Weiler; Fabian Kiessling; Twan Lammers; Roger M. Pallares
Opublikowane w: Molecular Pharmaceutics, Numer 1, 2021, ISSN 1543-8384
Wydawca: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.2c00416

Hydrophobic ion pairing enables co-loading of water-soluble drugs in polymeric micelles

Autorzy: Armin Azadkhah Shalmani, Rasika Daware, Asmaa Said Elshafei, Federica De Lorenzi, Diana Moeckel, Eva M. Buhl, Barbara Mara Klinkhammer, Peter Boor, Srinivas Banala, Alina Adams, Fabian Kiessling, Gert Storm, Josbert M. Metselaar, Alexandros Marios Sofias, Yang Shi, Twan Lammers, Quim Peña, Tarun Ojha
Opublikowane w: Journal of Controlled Release, Numer 1-13, 2025, Strona(/y) 113748, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2025.113748

Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis

Autorzy: Filip M E Segers, Adele V Ruder, Marijke M Westra, Twan Lammers, Seyed Mohammadali Dadfar, Karolin Roemhild, Tin Sing Lam, Marianne Eline Kooi, Kitty B J M Cleutjens, Fons K Verheyen, Geert W H Schurink, Guido R Haenen, Theo J C van Berkel, Ilze Bot, Bente Halvorsen, Judith C Sluimer, Erik A L Biessen
Opublikowane w: Cardiovascular Research, Numer 118, 2024, Strona(/y) 3346-3359, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvac032

Role of Surface Curvature in Gold Nanostar Properties and Applications

Autorzy: Zhongqian Xi, Rui Zhang, Fabian Kiessling, Twan Lammers, Roger M. Pallares
Opublikowane w: ACS Biomaterials Science & Engineering, Numer 10, 2024, Strona(/y) 38-50, ISSN 2373-9878
Wydawca: ACS
DOI: 10.1021/acsbiomaterials.3c00249

Improving MPI and hyperthermia performance of superparamagnetic iron oxide nanoparticles through fractional factorial design of experiments

Autorzy: Yanchen Li, Rui Zhang, Roman Barmin, Elena Rama, Max Schoenen, Franziska Schrank, Volkmar Schulz, Ioana Slabu, Fabian Kiessling, Twan Lammers, Roger M. Pallares
Opublikowane w: Nanoscale Advances, Numer 6, 2024, Strona(/y) 4352-4359, ISSN 2516-0230
Wydawca: RSC
DOI: 10.1039/d4na00378k

Bridging The Gap Between Lab and Clinic for Nanodiagnostics

Autorzy: Roger M Pallares, Fabian Kiessling, Twan Lammers
Opublikowane w: Nanomedicine, Numer 18, 2024, Strona(/y) 413-416, ISSN 1743-5889
Wydawca: Future Medicine Ltd.
DOI: 10.2217/nnm-2023-0067

Ultrasound-directed enzyme-prodrug therapy (UDEPT) using self-immolative doxorubicin derivatives

Autorzy: Karolin Roemhild, Helena C. Besse, Bi Wang, Quim Peña, Qingxue Sun, Daiki Omata, Burcin Ozbakir, Clemens Bos, Hans W. Scheeren, Gert Storm, Josbert M. Metselaar, Haijun Yu, Ruth Knüchel-Clarke, Fabian Kiessling, Chrit T.W. Moonen, Roel Deckers, Yang Shi, Twan Lammers
Opublikowane w: Theranostics, Numer 12, 2022, Strona(/y) 4791-4801, ISSN 1838-7640
Wydawca: Ivyspring International Publisher
DOI: 10.7150/thno.69168

Nanoparticles for Cancer Diagnosis, Radionuclide Therapy and Theranostics.

Autorzy: Jordi Llop; Twan Lammers
Opublikowane w: ACS Nano, Numer 19360851, 2021, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.1c09139

The success of nanomedicine

Autorzy: Twan Lammers, Mauro Ferrari
Opublikowane w: Nano Today, Numer 31, 2020, Strona(/y) 100853, ISSN 1748-0132
Wydawca: Elsevier BV
DOI: 10.1016/j.nantod.2020.100853

Repurposing Tamoxifen for Tumor Microenvironment Priming and Enhanced Tumor‐Targeted Drug Delivery

Autorzy: Ilaria Biancacci, Daniele De Santis, Elena Rama, Karina Benderski, Jeffrey Momoh, Robert Pohlberger, Diana Moeckel, Leonard Kaps, Cristianne J. F. Rijcken, Jai Prakash, Marielle Thewissen, Fabian Kiessling, Yang Shi, Quim Peña, Alexandros Marios Sofias, Lorena Consolino, Twan Lammers
Opublikowane w: Advanced Therapeutics, Numer 6, 2023, ISSN 2366-3987
Wydawca: Wiley
DOI: 10.1002/adtp.202300098

Neutrophil Hitchhiking Enhances Liposomal Dexamethasone Therapy of Sepsis

Autorzy: Ritvik Mathur, Sara Elsafy, Adrian T. Press, Julian Brück, Mathias Hornef, Lukas Martin, Tobias Schürholz, Gernot Marx, Matthias Bartneck, Fabian Kiessling, Josbert Maarten Metselaar, Gert Storm, Twan Lammers, Alexandros Marios Sofias, Patrick Koczera
Opublikowane w: ACS Nano, Numer 18, 2024, Strona(/y) 28866-28880, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.4c09054

Targeting Kidney Fibrosis with Polymeric Nanocarriers

Autorzy: Vedangi Kulkarni, Tim Caspers, Diana Moeckel, Susanne Koletnik, Elena Rama, Paraskevi Sotiropoulou, Daniel R. Dietrich, Robert Pola, Lenka Kotrchová, Tomáš Etrych, Yvonne H. W. Derks, Peter Boor, Fabian Kiessling, Felix M. Mottaghy, Barbara M. Klinkhammer, Twan Lammers
Opublikowane w: Chemistry of Materials, Numer 36, 2024, Strona(/y) 9686-9695, ISSN 0897-4756
Wydawca: American Chemical Society
DOI: 10.1021/acs.chemmater.4c01788

Unraveling the Seedless Growth of Gold Nanostars through Fractional Factorial Design

Autorzy: Rui Zhang; Fabian Kiessling; Twan Lammers; Roger M. Pallares
Opublikowane w: Journal of Physical Chemistry C, Numer 3, 2023, ISSN 1932-7447
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpcc.2c06396

Analysis of multi-drug cancer nanomedicine

Autorzy: Karina Benderski, Twan Lammers, Alexandros Marios Sofias
Opublikowane w: Nature Nanotechnology, 2025, ISSN 1748-3387
Wydawca: Nature Publishing Group
DOI: 10.1038/s41565-025-01932-1

Controlled Covalent Self‐Assembly of a Homopolymer for Multiscale Materials Engineering

Autorzy: Xiangyang Bai; Qingxue Sun; Hao Cui; Luis P. B. Guerzoni; Stefan Wuttke; Fabian Kiessling; Laura De Laporte; Twan Lammers; Yang Shi
Opublikowane w: Advanced Materials, Numer 1, 2022, ISSN 1521-4095
Wydawca: Wiley
DOI: 10.1002/adma.202109701

Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles

Autorzy: Ilaria Biancacci; Federica De Lorenzi; Benjamin Theek; Xiangyang Bai; Jan‐Niklas May; Lorena Consolino; Maike Baues; Diana Moeckel; Felix Gremse; Saskia Stillfried; Asmaa El Shafei; Karina Benderski; Armin Azadkhah Shalmani; Alec Wang; Jeffrey Momoh; Quim Peña; Eva Miriam Buhl; Johannes Buyel; Wim Hennink; Fabian Kiessling; Josbert Metselaar; Yang Shi; Twan Lammers
Opublikowane w: "Advanced science 2103745 (2022). doi:10.1002/advs.202103745 special issue: ""This article also appears in: Hot Topic: Tumors and Cancer""", Numer 21983844, 2022, ISSN 2198-3844
Wydawca: Wiley
DOI: 10.18154/rwth-2022-00963

Non-invasive molecular imaging of kidney diseases

Autorzy: Barbara M. Klinkhammer, Twan Lammers, Felix M. Mottaghy, Fabian Kiessling, Jürgen Floege, Peter Boor
Opublikowane w: Nature Reviews Nephrology, Numer 17/10, 2021, Strona(/y) 688-703, ISSN 1759-5061
Wydawca: Nature Publishing Group
DOI: 10.1038/s41581-021-00440-4

Polymeric antibubbles with strong ultrasound imaging capabilities

Autorzy: Roman A. Barmin, Jens Köhler, Michael Pohl, Bea Becker, Fabian Kiessling, Twan Lammers, Albert T. Poortinga, Roger M. Pallares
Opublikowane w: Chemical Communications, Numer 60, 2024, Strona(/y) 13340-13343, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d4cc03572k

Transformative Materials for Interfacial Drug Delivery

Autorzy: Prachi Desai, Anshuman Dasgupta, Alexandros Marios Sofias, Quim Peña, Robert Göstl, Ioana Slabu, Ulrich Schwaneberg, Thomas Stiehl, Wolfgang Wagner, Stefan Jockenhövel, Julia Stingl, Rafael Kramann, Christian Trautwein, Tim H. Brümmendorf, Fabian Kiessling, Andreas Herrmann, Twan Lammers
Opublikowane w: Advanced Healthcare Materials, Numer 12, 2023, ISSN 2192-2640
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202301062

RGD-coated polymeric microbubbles promote ultrasound-mediated drug delivery in an inflamed endothelium-pericyte co-culture model of the blood-brain barrier

Autorzy: Christopher Hark, Junlin Chen, Julia Blöck, Eva Miriam Buhl, Harald Radermacher, Robert Pola, Michal Pechar, Tomáš Etrych, Quim Peña, Anne Rix, Natascha I. Drude, Fabian Kiessling, Twan Lammers, Jan-Niklas May
Opublikowane w: Drug Delivery and Translational Research, Numer 14, 2024, Strona(/y) 2629-2641, ISSN 2190-393X
Wydawca: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01561-6

Metallodrugs in cancer nanomedicine

Autorzy: Quim Peña; Alec Wang; Orysia Zaremba; Yang Shi; Hans W. Scheeren; Josbert M. Metselaar; Fabian Kiessling; Roger M. Pallares; Stefan Wuttke; Twan Lammers
Opublikowane w: Chemical Society Reviews, Numer 1, 2022, ISSN 0306-0012
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1cs00468a

Roadmap on nanomedicine

Autorzy: Paolo Decuzzi, Dan Peer, Daniele Di Mascolo, Anna Lisa Palange, Purnima Naresh Manghnani, S Moein Moghimi, Z Shadi Farhangrazi, Kenneth A Howard, Daniel Rosenblum, Tingxizi Liang, Zhaowei Chen, Zejun Wang, Jun-Jie Zhu, Zhen Gu, Netanel Korin, Didier Letourneur, Cédric Chauvierre, Roy van der Meel, Fabian Kiessling, Twan Lammers
Opublikowane w: Nanotechnology, Numer 32/1, 2021, Strona(/y) 012001, ISSN 0957-4484
Wydawca: Institute of Physics Publishing
DOI: 10.1088/1361-6528/abaadb

Therapeutic and diagnostic targeting of fibrosis in metabolic, proliferative and viral disorders

Autorzy: Alexandros Marios Sofias, Federica De Lorenzi, Quim Peña, Armin Azadkhah Shalmani, Mihael Vucur, Jiong-Wei Wang, Fabian Kiessling, Yang Shi, Lorena Consolino, Gert Storm, Twan Lammers
Opublikowane w: Advanced Drug Delivery Reviews, Numer 175, 2021, Strona(/y) 113831, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2021.113831

Lipids in disease pathology, diagnosis & therapy

Autorzy: Twan Lammers, Heidi Noels
Opublikowane w: Advanced Drug Delivery Reviews, Numer 159, 2020, Strona(/y) 1-3, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2020.11.006

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