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MOVING FROM BIOMARKERS TO MECHANISM ORIENTED PREVENTION OF CARDIOMETABOLIC DISEASE

Publikacje

Metabolome-Defined Obesity and the Risk of Future Type 2 Diabetes and Mortality

Autorzy: Ottosson F, Smith E, Ericson U, Brunkwall L, Orho-Melander M, Di Somma S, Antonini P, Nilsson PM, Fernandez C, Melander O
Opublikowane w: Diabetes Care, 2022, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dc21-2402

Effect of Monoclonal Antibody Blockade of Long Fragment Neurotensin on Weight Loss, Behavior, and Metabolic Traits After High-Fat Diet Induced Obesity

Autorzy: Wu Z, Stadler N, Abbaci A, Liu J, Boullier A, Marie N, Biondi O, Moldes M, Morichon R, Feve B, Melander O, Forgez P
Opublikowane w: Frontiers in Endocrinology (Lausanne), 2021, ISSN 1664-2392
Wydawca: Lausanne: Frontiers Media S.A., 2010-
DOI: 10.3389/fendo.2021.739287

Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes.

Autorzy: Akbari P, Sosina OA, Bovijn J, Landheer K, Nielsen JB, Kim M, Aykul S, De T, Haas ME, Hindy G, Lin N, Dinsmore IR, Luo JZ, Hectors S, Geraghty B, Germino M, Panagis L, Parasoglou P, Walls JR, Halasz G, Atwal GS; Regeneron Genetics Center; DiscovEHR Collaboration, Jones M, LeBlanc MG, Still CD, Carey DJ, Giontella A, Orho-Melander M, Berumen J, Kuri-Morales P, Alegre-Díaz J, Torres JM, Emberson JR
Opublikowane w: Nature Communications, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-32398-7

Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting

Autorzy: Giontella A, Sjögren M, Lotta LA, Overton JD, Baras A, Regeneron Genetics Center, Minuz P, Fava C, Melander O
Opublikowane w: Hypertension (Dallas, Tex. : 1979), 2020, ISSN 0194-911X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.120.15449

Novel insights into peptide amidation and amidating activity in the human circulation

Autorzy: Kaufmann P, Bergmann A, Melander O
Opublikowane w: Scientific Reports, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-95305-y

A plasma lipid signature predicts incident coronary artery disease.

Autorzy: Ottosson F, Emami Khoonsari P, Gerl MJ, Simons K, Melander O, Fernandez C.
Opublikowane w: International Journal of Cardiology, Numer 15, 2021, Strona(/y) 249-254, ISSN 0167-5273
Wydawca: Elsevier BV
DOI: 10.1016/j.ijcard.2021.01.059

Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease

Autorzy: Hindy G, Aragam KG, Ng K, Chaffin M, Lotta LA, Baras A, Regeneron Genetics Center, Drake I, Orho-Melander M, Melander O, Kathiresan S, Khera AV
Opublikowane w: Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, ISSN 1079-5642
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.120.314856

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort

Autorzy: Lauber C, Gerl MJ, Klose C, Ottosson F, Melander O, Simons K
Opublikowane w: PLoS Biology, 2022, ISSN 1544-9173
Wydawca: Public Library of Science
DOI: 10.1371/journal.pbio.3001561

Proteomic and Metabolomic Characterization of Metabolically Healthy Obesity: A Descriptive Study from a Swedish Cohort

Autorzy: Korduner J, Nilsson PM, Melander O, Gerl MJ, Engström G, Bachus E, Magnusson M, Ottosson F
Opublikowane w: Journal of Obesity, 2021, ISSN 2090-0708
Wydawca: Hindawi Publishing Corporation
DOI: 10.1155/2021/6616983

Comparison of cardiovascular disease and cancer prevalence between Mediterranean and north European middle-aged populations (The Cilento on Ageing Outcomes Study and The Malmö Offspring Study)

Autorzy: Melander O, Antonini P, Ottosson F, Brunkwall L, Gallo W, Nilsson PM, Orho-Melander M, Pacente G, D'Arena G, Di Somma S
Opublikowane w: Internal and Emergency Medicine, 2021, ISSN 1828-0447
Wydawca: CEPI-AIM Group
DOI: 10.1007/s11739-020-02625-4

Replication study reveals miR-483-5p as an important target in prevention of cardiometabolic disease

Autorzy: Gallo W, Ottosson F, Kennbäck C, Jujic A, Esguerra JLS, Eliasson L, Melander O
Opublikowane w: BMC Cardiovascular Disorders, 2021, ISSN 1471-2261
Wydawca: BioMed Central
DOI: 10.1186/s12872-021-01964-0

High pro-neurotensin levels in individuals with type 1 diabetes associate with the development of cardiovascular risk factors at follow-up.

Autorzy: Cimini FA, Barchetta I, Bertoccini L, Ceccarelli V, Baroni MG, Melander O, Cavallo MG.
Opublikowane w: Acta Diabetologica, Numer 59, 2021, Strona(/y) 49-56, ISSN 0940-5429
Wydawca: Springer Verlag
DOI: 10.1007/s00592-021-01783-x

Pro-Enkephalin and its association with renal function in Middle Eastern immigrants and native Swedes

Autorzy: Nilsson C, Christensson A, Nilsson PM, Melander O, Bennet L
Opublikowane w: Scandinavian Journal of Clinical and Laboratory Investigation, 2021, ISSN 0036-5513
Wydawca: Taylor & Francis
DOI: 10.1080/00365513.2021.1979243

A healthy dietary metabolic signature is associated with a lower risk for type 2 diabetes and coronary artery disease

Autorzy: Smith E, Ericson U, Hellstrand S, Orho-Melander M, Nilsson PM, Fernandez C, Melander O, Ottosson F
Opublikowane w: BMC Medicine, 2022, ISSN 1741-7015
Wydawca: BioMed Central
DOI: 10.1186/s12916-022-02326-z

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