MAgnetically steerable wireless Nanodevices for the tarGeted delivery of therapeutIc agents in any vascular rEgion of the body

Informacje na temat projektu

ANGIE

Identyfikator umowy o grant: 952152

DOI

10.3030/952152

Projekt został zamknięty

Data podpisania przez KE 29 Maja 2020

Data rozpoczęcia 1 Stycznia 2021

Data zakończenia 31 Grudnia 2024

Finansowanie w ramach

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Koszt całkowity

€ 4 000 000,00

Wkład UE

€ 4 000 000,00

Koordynowany przez

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (10)

Report on the interface between electromagnetic and angiography systems

s.a.

Report 1 on actions to create interdisciplin. community around targeted drug delivery

sa

Report 3 on measures to create innovation eco-system around ANGIE technology

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Dissemination and Communication Plan

sa

Dissemination and Communication Plan update 1

s.a.

Report 3 on actions to create interdisciplinary community around targeted drug delivery

s.a.

Report 1 on measures to create innovation eco-system around ANGIE technology

sa

Dissemination and Communication Plan update 2

s.a.

Report 2 on actions to create interdisciplinary community around targeted drug delivery

s.a.

Report 2 on measures to create innovation eco-system around ANGIE technology

s.a.

Demonstrators, pilots, prototypes (2)

Prototype of electromagnetic system for navigation and actuation

s.a.

Perfused 3D models of the vascular network with different tortuosity and clot sites

s.a.

Publikacje

Peer reviewed articles (19)

3D Printed Template-Assisted Casting of Biocompatible Polyvinyl Alcohol-Based Soft Microswimmers with Tunable Stability

Autorzy: Roger Sanchis-Gual, Hao Ye, Towa Ueno, Fabian C. Landers, Lukas Hertle, Siyu Deng, Andrea Veciana, Yanming Xia, Carlos Franco, Hongsoo Choi, Josep Puigmartí-Luis, Bradley J. Nelson, Xiang-Zhong Chen, Salvador Pané
Opublikowane w: Advanced functional materials, 2023, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202212952

A Human‐Scale Clinically Ready Electromagnetic Navigation System for Magnetically Responsive Biomaterials and Medical Devices

Autorzy: Simone Gervasoni, Norman Pedrini, Tarik Rifai, Cedric Fischer, Fabian C. Landers, Michael Mattmann, Roland Dreyfus, Silvia Viviani, Andrea Veciana, Enea Masina, Buse Aktas, Josep Puigmartí‐Luis, Christophe Chautems, Salvador Pané, Quentin Boehler, Philipp Gruber, Bradley J. Nelson
Opublikowane w: Advanced Materials, Numer 36, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202310701

Patient-specific placental vessel segmentation with limited data

Autorzy: Gary Sarwin, Jonas Lussi, Simone Gervasoni, Ueli Moehrlen, Nicole Ochsenbein, Bradley J. Nelson
Opublikowane w: Journal of Robotic Surgery, Numer 18, 2024, ISSN 1863-2483
Wydawca: Springer Verlag
DOI: 10.1007/s11701-024-01981-z

A novel nutraceutical formulation increases telomere length and activates telomerase activity in middle‑aged rats

Autorzy: Aristidis Tsatsakis Elisavet Renieri Dimitris Tsoukalas Ana Maria Buga Evangelia Sarandi Elena Vakonaki Persefoni Fragkiadaki Athanasios Alegakis Dragana Nikitovic Daniela Calina Demetrios A. Spandidos Anca Oana Docea
Opublikowane w: Molecular Medicine Reports, Numer Volume 28, Numer 6, 2023, ISSN 1791-2997
Wydawca: Spandidos Publications
DOI: 10.3892/mmr.2023.13119

Advancing athletic assessment by integrating conventional methods with cutting-edge biomedical technologies for comprehensive performance, wellness, and longevity insights

Autorzy: Spanakis Marios, Fragkiadaki Persefoni, Renieri Elisavet, Vakonaki Elena, Fragkiadoulaki Irene, Alegakis Athanasios, Kiriakakis Mixalis, Panagiotou Nikolaos, Ntoumou Eleni, Gratsias Ioannis, Zoubaneas Evangelos, Morozova Galina Dmitrievna, Ovchinnikova Marina Alekseevna, Tsitsimpikou Christina, Tsarouhas Konstantinos, Drakoulis Nikolaos, Skalny Anatoly Viktorovich, Tsatsakis Aristides
Opublikowane w: Frontiers in Sports and Active Living, 2024, ISSN 2624-9367
Wydawca: Frontiers
DOI: 10.3389/fspor.2023.1327792

Toward More Inclusive Networks and Initiatives in Innovation Ecosystems: Protocol for a Systematic Review

Autorzy: Georgia Ntina; Eirini Mavromanolaki; Andreas D Flouris
Opublikowane w: JMIR Research Protocol, 2022, Strona(/y) e34071, ISSN 1929-0748
Wydawca: JMIR Publications Inc.
DOI: 10.2196/34071

Magnetically Guided Microcatheter for Targeted Injection of Magnetic Particle Swarms

Autorzy: Harun Torlakcik, Semih Sevim, Pedro Alves, Michael Mattmann, Joaquim Llacer‐Wintle, Maria Pinto, Rosa Moreira, Andreas D. Flouris, Fabian C. Landers, Xiang‐Zhong Chen, Josep Puigmartí‐Luis, Quentin Boehler, Tiago Sotto Mayor, Minsoo Kim, Bradley J. Nelson, Salvador Pané
Opublikowane w: Advanced Science, Numer 11, 2024, ISSN 2198-3844
Wydawca: Weinheim: Wiley-VCH
DOI: 10.1002/advs.202404061

Single‐Step Synthesis of Sub‐10 nm Magnetic Nanoparticles with High Saturation Magnetization and Broad pH Stability

Autorzy: Vitaly Pustovalov, Fabian C. Landers, Lukas Hertle, Hyeon Ko, Joaquin Llacer‐Wintle, Hao Ye, Andrea Veciana, Carlos Franco, Roger Sanchis‐Gual, Xiang‐Zhong Chen, Eva Pellicer, Josep Puigmartí‐Luis, Bradley J. Nelson, Salvador Pané
Opublikowane w: Advanced Engineering Materials, Numer 26, 2024, ISSN 1438-1656
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adem.202400307

A Naturally Inspired Extrusion‐Based Microfluidic Approach for Manufacturing Tailorable Magnetic Soft Continuum Microrobotic Devices

Autorzy: Lukas Hertle, Semih Sevim, Jiawei Zhu, Vitaly Pustovalov, Andrea Veciana, Joaquin Llacer‐Wintle, Fabian C. Landers, Hao Ye, Xiang‐Zhong Chen, Hannes Vogler, Ueli Grossniklaus, Josep Puigmartí‐Luis, Bradley J. Nelson, Salvador Pané
Opublikowane w: Advanced Materials, Numer 36, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202402309

Shape‐Morphing in Oxide Ceramic Kirigami Nanomembranes

Autorzy: Minsoo Kim, Donghoon Kim, Mathieu Mirjolet, Nick A. Shepelin, Thomas Lippert, Hongsoo Choi, Josep Puigmartí‐Luis, Bradley J. Nelson, Xiang‐Zhong Chen, Salvador Pané
Opublikowane w: Advanced Materials, Numer 36, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202404825

Simultaneous Localization and Actuation Using Electromagnetic Navigation Systems

Autorzy: Von Arx Denis; Fischer Cedric; Torlakcik Harun; Pané Salvador; Nelson Bradley; J.Boehler Quentin
Opublikowane w: Simultaneous Localization and Actuation Using Electromagnetic Navigation Systems, 2023, ISSN 1552-3098
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TRO.2023.3340324

On-Command Disassembly of Microrobotic Superstructures for Transport and Delivery of Magnetic Micromachines

Autorzy: F. C. Landers, V. Gantenbein, L. Hertle, A. Veciana, J. Llacer-Wintle, X.-Z. Chen, H. Ye, C. Franco, J. Puigmartí-Luis, M. Kim, B. J. Nelson, S. Pané
Opublikowane w: Advanced Materials, 2023, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202310084

3D Motion Manipulation for Micro- and Nanomachines: Progress and Future Directions

Autorzy: Hai Huang, Shihao Yang, Yulong Ying, Xiangzhong Chen, Josep Puigmartí-Luis, Li Zhang, Salvador Pané
Opublikowane w: Advanced Materials, 2023, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202305925

Autonomous 3D positional control of a magnetic microrobot using reinforcement learning

Autorzy: Sarmad Ahmad Abbasi, Awais Ahmed, Seungmin Noh, Nader Latifi Gharamaleki, Seonhyoung Kim, A. M. Masum Bulbul Chowdhury, Jin-young Kim, Salvador Pané, Bradley J. Nelson, Hongsoo Choi
Opublikowane w: Nature Machine Intelligence, Numer 6, 2024, Strona(/y) 92-105, ISSN 2522-5839
Wydawca: NPG
DOI: 10.1038/s42256-023-00779-2

Magnetically Assisted Robotic Fetal Surgery for the Treatment of Spina Bifida

Autorzy: Gervasoni, Simone; Lussi, Jonas; Viviani, Silvia; Boehler, Quentin; Ochsenbein, Nicole; Moehrlen, Ueli; Nelson, Bradley J.; Gervasoni, Simone
Opublikowane w: IEEE Transactions on Medical Robotics and Bionics, 2022, Strona(/y) 85-93, ISSN 2576-3202
Wydawca: IEEE
DOI: 10.3929/ethz-b-000531109

Magnetically Guided Laser Surgery for the Treatment of Twin-to-Twin Transfusion Syndrome

Autorzy: Lussi, J., Gervasoni, S., Mattille, M., Dreyfus, R., Boehler, Q., Reinehr, M., Ochsenbein, N., Nelson, B.J. and Moehrlen, U.
Opublikowane w: Advanced Intelligent Systems, Numer Volume 4, Numer 11, 2022, ISSN 2640-4567
Wydawca: Wiley-VCH GmbH
DOI: 10.1002/aisy.202200182

Site-specific PEGylation of recombinant tissue-type plasminogen activator

Autorzy: Kirstin Meiners, Prisca Hamm, Marcus Gutmann, Jan Niedens, Agnieszka Nowak-Król, Salvador Pané, Tessa Lühmann
Opublikowane w: European Journal of Pharmaceutics and Biopharmaceutics, Numer Volume 192, 2023, Strona(/y) 79-87, ISSN 0939-6411
Wydawca: Elsevier BV
DOI: 10.1016/j.ejpb.2023.09.017

Powering and Fabrication of Small-Scale Robotics Systems

Autorzy: Salvador Pané; Pedro D. Wendel-García; Yonca Belce; Xiang-Zhong Chen; Josep Puigmartí-Luis
Opublikowane w: Current Robotics Reports, Numer 2, 2021, Strona(/y) 1 - 14, ISSN 2662-4087
Wydawca: Springer
DOI: 10.1007/s43154-021-00066-1

Dexterous helical magnetic robot for improved endovascular access

Autorzy: Dreyfus R, Boehler Q, Lyttle S, Gruber P, Lussi J, Chautems C, Gervasoni S, Berberat J, Seibold D, Ochsenbein-Kölble N, Reinehr M, Weisskopf M, Remonda L, Nelson BJ. Dexterous helical magnetic robot for improved endovascular access.
Opublikowane w: Science Robotics, Numer Vol 9, Numer 87, 2024, ISSN 2470-9476
Wydawca: American Association for the Advancement of Science
DOI: 10.3929/ethz-b-000659728

Conference proceedings (8)

In Vitro Navigation of a Magnetic Sphere using a Model Predictive Controller for Neurovascular Targeted Drug Delivery Applications

Autorzy: null null, D Sivakumaran, F. C Landers, Q Boehler, C Chautems, S Pané, B. J Nelson, null null
Opublikowane w: Proceedings of The 14th Hamlyn Symposium on Medical Robotics 2022, 2022, Strona(/y) 109-110
Wydawca: The Hamlyn Centre, Imperial College London London, UK
DOI: 10.31256/hsmr2022.54

Soft-hard magnetically driven microrobotic devices

Autorzy: F C Landers; C. J. Alcantara; Josep Puigmartí-Luis; Bradley J. Nelson; Salvador Pané
Opublikowane w: Public Health and Toxicology, 2021
Wydawca: EU European Publishing
DOI: 10.18332/pht/142296

Microfluidic technologies for chemistry, materials science and biotechnology

Autorzy: Josep Puigmartí-Luis
Opublikowane w: Public Health and Toxicology, 2021
Wydawca: EU European Publishing
DOI: 10.18332/pht/142301

Magnetic small-scale robots: Principles, applications and challenges

Autorzy: Salvador Pané; J. Puigmartí; M. Pinto; E. Mavromanolaki; A. Flouris; T. S. Mayor; Tessa Lühmann; D. Sargent; Bradley J. Nelson
Opublikowane w: Public Health and Toxicology, 2021
Wydawca: EU European Publishing
DOI: 10.3929/ethz-b-000526973

Evolution, gaps, and trends in the origins of innovation ecosystems

Autorzy: E. Mavromanolaki; G. Ntina; S. Karatsali; P. Smarianaki; M. Pinto; R. Moreira; S. Pané; T. S. Mayor, J; Puigmartí; A. D. Flouris
Opublikowane w: Public Health and Toxicology, 2021
Wydawca: EU European Publishing
DOI: 10.18332/pht/142303

In flow controlled synthesis of blood clots

Autorzy: R. S. Herrera-Restrepo; P. Martinez-Bulit; A. D. Flouris; M. Pinto; R. Moreira; E. Mavromanolaki; T. S. Mayor; S. Pané; J. Ignés; and J. Puigmartí-Luis
Opublikowane w: Public Health and Toxicology, 2021
Wydawca: EU European Publishing
DOI: 10.18332/pht/142302

3D interlocked metal-organic magnetic microrobots

Autorzy: F. Landers; S. Pané
Opublikowane w: International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), 2022
Wydawca: MARSS

Marrying inorganics and biologics: Opportunities and challenges

Autorzy: K. Meiners; M. Richter; F. Landers; S. Pané; T. Lühmann
Opublikowane w: Public Health and Toxicology, 2021
Wydawca: EU European Publishing
DOI: 10.18332/pht/142300

Monographic books (1)

Emerging Issues on Targeted Drug Delivery

Autorzy: Vliora Maria, Tsatsakis Aristidis, Kallinteri Paraskevi, Kallkach Aparicio Mariel
Opublikowane w: 2024, Strona(/y) Scientific Research Publishing, ISBN 979-8-89507-901-0
Wydawca: Scientific Research Publishing
DOI: 10.5281/zenodo.14621049

Non-peer reviewed articles (1)

Clinically Ready Magnetic Microrobots for Targeted Therapies

Autorzy: Fabian C. Landers, Lukas Hertle, Vitaly Pustovalov, Derick Sivakumaran, Oliver Brinkmann, Kirstin Meiners, Pascal Theiler, Valentin Gantenbein, Andrea Veciana, Michael Mattmann, Silas Riss, Simone Gervasoni, Christophe Chautems, Hao Ye, Semih Sevim, Andreas D. Flouris, Josep Puigmartí-Luis, Tiago Sotto Mayor, Pedro Alves, Tessa Lühmann, Xiangzhong Chen, Nicole Ochsenbein, Ueli Moehrlen, Philipp
Opublikowane w: arXiv, 2025, ISSN 2331-8422
Wydawca: Cornell University
DOI: 10.48550/arxiv.2501.11553