Epileptogenesis and Epilepsy Network: from genes, synapses and circuits to pave the way for novel drugs and strategies

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Public sessions and debates on epilepsy final assessment
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Publikacje

A Model of Epileptogenesis in Rhinal Cortex-Hippocampus Organotypic Slice Cultures

Autorzy: Cláudia A. Valente; Francisco J Meda; Mafalda Carvalho; Ana M. Sebastião
Opublikowane w: Journal of Visualized Experiments, Numer 24, 2021, ISSN 1940-087X
Wydawca: MYJoVE Corporation
DOI: 10.3791/61330

miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex

Autorzy: Mirte Scheper, Alessia Romagnolo, Zein Mersini Besharat, Anand M. Iyer, Romina Moavero, Christoph Hertzberg, Bernhard Weschke, Kate Riney, Martha Feucht, Theresa Scholl, Borivoj Petrak, Alice Maulisova, Rima Nabbout, Anna C. Jansen, Floor E. Jansen, Lieven Lagae, Malgorzata Urbanska, Elisabetta Ferretti, Aleksandra Tempes, Magdalena Blazejczyk, Jacek Jaworski, David J. Kwiatkowski, Sergiusz Jozwia
Opublikowane w: Biomedicines, Numer 10, 2024, Strona(/y) 1838, ISSN 2227-9059
Wydawca: MDPI
DOI: 10.3390/biomedicines10081838

Lineage-specific changes in mitochondrial properties during neural stem cell differentiation

Autorzy: Rita Soares, Diogo M Lourenço, Isa F Mota, Ana M Sebastião, Sara Xapelli, Vanessa A Morais
Opublikowane w: Life Science Alliance, Numer 7, 2024, Strona(/y) e202302473, ISSN 2575-1077
Wydawca: Life Science Alliance LLC
DOI: 10.26508/lsa.202302473

Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy

Autorzy: Diogo M Lourenço, Leonor Ribeiro-Rodrigues, Ana M Sebastião, Maria J Diógenes, Sara Xapelli.
Opublikowane w: International Journal of Molecular Sciences, 2020, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21197309

Histopathological characterization of cerebral small vessel disease in epilepsy patients with temporal lobe epilepsy submitted to surgery: A case–control study

Autorzy: Pedro Coelho, João Madureira, Ana Franco, Ana Rita Peralta, Carla Bentes, Alexandre Rainha Campos, Jasper Anink, Eleonora Aronica, Rafael Roque, José Pimentel
Opublikowane w: European Journal of Neurology, Numer 30, 2023, Strona(/y) 2999-3007, ISSN 1351-5101
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/ene.15963

Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress

Autorzy: R. S. Rodrigues, J. B. Moreira, J. M. Mateus, A. Barateiro, S. L. Paulo, S. H. Vaz, D. M. Lourenço, F. F. Ribeiro, R. Soares, E. Loureiro-Campos, P. Bielefeld, A. M. Sebastião, A. Fernandes, L. Pinto, C. P. Fitzsimons, S. Xapelli
Opublikowane w: Translational Psychiatry, Numer 14, 2024, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.1038/s41398-024-02877-0

Unexpected Effect of IL-1β on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia

Autorzy: Veronica Alfano, Alessia Romagnolo, James D. Mills, Pierangelo Cifelli, Alessandro Gaeta, Alessandra Morano, Angelika Mühlebner, Eleonora Aronica, Eleonora Palma, Gabriele Ruffolo
Opublikowane w: Brain Sciences, Numer 12, 2024, Strona(/y) 807, ISSN 2076-3425
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci12060807

NLRP3 Inflammasome: A Starring Role in Amyloid-β- and Tau-Driven Pathological Events in Alzheimer’s Disease

Autorzy: Mariana Van Zeller, Diogo Dias, Ana M. Sebastião, Cláudia A. Valente
Opublikowane w: Journal of Alzheimer's Disease, Numer 83, 2023, Strona(/y) 939-961, ISSN 1387-2877
Wydawca: IOS Press
DOI: 10.3233/jad-210268

Late-onset seizures and epilepsy: Electroclinical features suggestive of autoimmune etiology

Autorzy: Alessandra Morano, Emanuele Cerulli Irelli, Enrico Michele Salamone, Biagio Orlando, Martina Fanella, Emanuele Tinelli, Gabriele Ruffolo, Luigi Zuliani, Jinane Fattouch, Mario Manfredi, Anna Teresa Giallonardo, Carlo Di Bonaventura
Opublikowane w: Frontiers in Neurology, Numer 13, 2022, ISSN 1664-2295
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.924859

Adenosine receptors are the on‐and‐off switch of astrocytic cannabinoid type 1 (<scp>CB1)</scp> receptor effect upon synaptic plasticity in the medial prefrontal cortex

Autorzy: Joana Gonçalves‐Ribeiro, Oksana K. Savchak, Sara Costa‐Pinto, Joana I. Gomes, Rafael Rivas‐Santisteban, Alejandro Lillo, Javier Sánchez Romero, Ana M. Sebastião, Marta Navarrete, Gemma Navarro, Rafael Franco, Sandra H. Vaz
Opublikowane w: Glia, Numer 72, 2024, Strona(/y) 1096-1116, ISSN 0894-1491
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/glia.24518

Effective reduction in seizure severity and prevention of a fatty liver by a novel low ratio ketogenic diet composition in the rapid kindling rat model of epileptogenesis

Autorzy: Hester Meeusen, Rozemarijn S. Kalf, Diede W.M. Broekaart, Jose P. Silva, J. Martin Verkuyl, Ardy van Helvoort, Jan A. Gorter, Erwin A. van Vliet, Eleonora Aronica
Opublikowane w: Experimental Neurology, Numer 379, 2024, Strona(/y) 114861, ISSN 0014-4886
Wydawca: Academic Press
DOI: 10.1016/j.expneurol.2024.114861

Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine

Autorzy: Daniela Sofia Abreu, Joana I. Gomes, Filipa F. Ribeiro, Maria J. Diógenes, Ana M. Sebastião, Sandra H. Vaz
Opublikowane w: Frontiers in Cellular Neuroscience, Numer 17, 2023, ISSN 1662-5102
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncel.2023.1282841

Plasma Biomarker Profile and Clinical Correlations in Adult Patients With Tuberous Sclerosis Complex

Autorzy: Biagio Orlando, Alessandra Morano, Valeria Manzini, Emanuele Cerulli Irelli, Maria S. Borioni, Caterina Veroni, Enrico Michele Salamone, Chiara D'Amelio, Elisa Moliterni, Sandra Giustini, Gabriele Ruffolo, Ivan Arisi, Mara D'Onofrio, Anna T. Giallonardo, Paola Piscopo, Carlo Di Bonaventura
Opublikowane w: Neurology, Numer 101, 2024, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000207799

Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer’s Disease-like Neuropathology in a Mouse Model for Down Syndrome

Autorzy: Antonella Tramutola, Simona Lanzillotta, Giuseppe Aceto, Sara Pagnotta, Gabriele Ruffolo, Pierangelo Cifelli, Federico Marini, Cristian Ripoli, Eleonora Palma, Claudio Grassi, Fabio Di Domenico, Marzia Perluigi, Eugenio Barone
Opublikowane w: Antioxidants, Numer 12, 2023, Strona(/y) 111, ISSN 2076-3921
Wydawca: MDPI
DOI: 10.3390/antiox12010111

Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy

Autorzy: Till S. Zimmer, Bastian David, Diede W. M. Broekaart, Martin Schidlowski, Gabriele Ruffolo, Anatoly Korotkov, Nicole N. van der Wel, Peter C. van Rijen, Angelika Mühlebner, Wim van Hecke, Johannes C. Baayen, Sander Idema, Liesbeth François, Jonathan van Eyll, Stefanie Dedeurwaerdere, Helmut W. Kessels, Rainer Surges, Theodor Rüber, Jan A. Gorter, James D. Mills, Erwin A. van Vliet, Eleonora Aro
Opublikowane w: Acta Neuropathologica, Numer 142, 2021, Strona(/y) 729-759, ISSN 0001-6322
Wydawca: Springer Verlag
DOI: 10.1007/s00401-021-02348-6

Adjusting the brakes to adjust neuronal activity: Adenosinergic modulation of GABAergic transmission

Autorzy: Ana M. Sebastião, Joaquim Alexandre Ribeiro
Opublikowane w: Neuropharmacology, Numer 236, 2023, Strona(/y) 109600, ISSN 0028-3908
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2023.109600

The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro

Autorzy: Diede W. M. Broekaart, Till S. Zimmer, Sophie T. Cohen, Rianne Tessers, Jasper J. Anink, Helga E. de Vries, Jan A. Gorter, Roger Prades, Eleonora Aronica, Erwin A. van Vliet
Opublikowane w: Biomedicines, Numer 10, 2024, Strona(/y) 2117, ISSN 2227-9059
Wydawca: MDPI
DOI: 10.3390/biomedicines10092117

Changes in adenosine receptors and neurotrophic factors in the SOD1G93A mouse model of amyotrophic lateral sclerosis: Modulation by chronic caffeine

Autorzy: Nádia Rei, Cláudia A. Valente, Sandra H. Vaz, Miguel Farinha-Ferreira, Joaquim A. Ribeiro, Ana M. Sebastião
Opublikowane w: PLOS ONE, Numer 17, 2022, Strona(/y) e0272104, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0272104

MicroRNA-34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis.

Autorzy: Anatoly Korotkov; Nam Suk Sim; Mark J. Luinenburg; Jasper J. Anink; Jackelien van Scheppingen; Jackelien van Scheppingen; Till S. Zimmer; Anika Bongaarts; Diede W. M. Broekaart; Caroline Mijnsbergen; Floor E. Jansen; Wim Van Hecke; Wim G.M. Spliet; Peter C. van Rijen; Martha Feucht; Johannes A. Hainfellner; Pavel Krsek; Josef Zamecnik; Peter B. Crino; Katarzyna Kotulska; Lieven Lagae; Anna Jansen;
Opublikowane w: VOLUME=47;ISSUE=6;STARTPAGE=796;ENDPAGE=811;ISSN=0305-1846;TITLE=Neuropathology and applied neurobiology, Numer 38, 2021, ISSN 1365-2990
Wydawca: Wiley Online Library
DOI: 10.1111/nan.12717

Manganese dioxide nanosheet-containing reactors as antioxidant support for neuroblastoma cells

Autorzy: Oksana K. Savchak, Nanying Wang, Miguel A. Ramos-Docampo, Paula de Dios Andres, Ana M. Sebastião, Filipa F. Ribeiro, Adam Armada-Moreira, Brigitte Städler, Sandra H. Vaz
Opublikowane w: Journal of Materials Chemistry B, Numer 10, 2024, Strona(/y) 4672-4683, ISSN 2050-7518
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2tb00393g

Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy

Autorzy: Pierangelo Cifelli, Silvia Di Angelantonio, Veronica Alfano, Alessandra Morano, Eleonora De Felice, Eleonora Aronica, Gabriele Ruffolo, Eleonora Palma
Opublikowane w: Brain Sciences, 2021, ISSN 2076-3425
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci11040441

Altered Extracellular Matrix as an Alternative Risk Factor for Epileptogenicity in Brain Tumors

Autorzy: Jody M. de Jong, Diede W. M. Broekaart, Anika Bongaarts, Angelika Mühlebner, James D. Mills, Erwin A. van Vliet, Eleonora Aronica
Opublikowane w: Biomedicines, Numer 10, 2024, Strona(/y) 2475, ISSN 2227-9059
Wydawca: Biomedicines
DOI: 10.3390/biomedicines10102475

mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment

Autorzy: Teresa Ravizza, Mirte Scheper, Rossella Di Sapia, Jan Gorter, Eleonora Aronica, Annamaria Vezzani
Opublikowane w: Nature Reviews Neuroscience, Numer 25, 2024, Strona(/y) 334-350, ISSN 1471-003X
Wydawca: Nature Publishing Group
DOI: 10.1038/s41583-024-00805-1

Bridging the gap of axonal regeneration in the central nervous system: A state of the art review on central axonal regeneration

Autorzy: Gonçalo Costa, Filipa F. Ribeiro, Ana M. Sebastião, Elizabeth M. Muir, Sandra H. Vaz
Opublikowane w: Frontiers in Neuroscience, Numer 16, 2023, ISSN 1662-453X
Wydawca: Frontiers in Neuroscience
DOI: 10.3389/fnins.2022.1003145

Astrocytes in the initiation and progression of epilepsy

Autorzy: Annamaria Vezzani, Teresa Ravizza, Peter Bedner, Eleonora Aronica, Christian Steinhäuser, Detlev Boison
Opublikowane w: Nature Reviews Neurology, Numer 18, 2022, Strona(/y) 707-722, ISSN 1759-4758
Wydawca: Nature Publishing Group
DOI: 10.1038/s41582-022-00727-5

Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury in rodents

Autorzy: Frances S. Cho, Ilia D. Vainchtein, Yuliya Voskobiynyk, Allison R. Morningstar, Francisco Aparicio, Bryan Higashikubo, Agnieszka Ciesielska, Diede W. M. Broekaart, Jasper J. Anink, Erwin A. van Vliet, Xinzhu Yu, Baljit S. Khakh, Eleonora Aronica, Anna V. Molofsky, Jeanne T. Paz
Opublikowane w: Science Translational Medicine, Numer 14, 2024, ISSN 1946-6234
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abj4310

Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia 2B brain lesions.

Autorzy: Victoria-Elisabeth Gruber, Mark J. Luinenburg, Katrin Colleselli, Verena Endmayr, J. Anink, Till S. Zimmer, Floor Jansen, Peter Gosselaar, Roland Coras, Theresa Scholl, Jackelien van Scheppingen, Ingmar Blumcke, José Pimentel, Johannes A. Hainfellner, Romana Höftberger, Karl Rössler, Martha Feucht, Eleonora Aronica, and Angelika Mühlebner.
Opublikowane w: Epilepsia, 2021, ISSN 1528-1167
Wydawca: Wiley Online Library
DOI: 10.1111/epi.17139

CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy

Autorzy: Rossella Di Sapia, Till S. Zimmer, Valentina Kebede, Silvia Balosso, Teresa Ravizza, Diletta Sorrentino, Manuel Alejandro Montano Castillo, Luca Porcu, Franca Cattani, Anna Ruocco, Eleonora Aronica, Marcello Allegretti, Laura Brandolini, Annamaria Vezzani
Opublikowane w: Neurobiology of Disease, Numer 158, 2022, Strona(/y) 105468, ISSN 0969-9961
Wydawca: Academic Press
DOI: 10.1016/j.nbd.2021.105468

Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex

Autorzy: Mirte Scheper, Frederik N. F. Sørensen, Gabriele Ruffolo, Alessandro Gaeta, Lilian J. Lissner, Jasper J. Anink, Irina Korshunova, Floor E. Jansen, Kate Riney, Wim van Hecke, Angelika Mühlebner, Konstantin Khodosevich, Dirk Schubert, Eleonora Palma, James D. Mills, Eleonora Aronica
Opublikowane w: Acta Neuropathologica, Numer 147, 2024, ISSN 0001-6322
Wydawca: Springer Verlag
DOI: 10.1007/s00401-024-02737-7

SIGAA: signaling automated analysis: a new tool for Ca2+ signaling quantification using ratiometric Ca2+ dyes

Autorzy: Rafael Faria Lopes, Joana Gonçalves-Ribeiro, Ana M. Sebastião, Carlos Meneses, Sandra H. Vaz
Opublikowane w: Signal, Image and Video Processing, Numer 18, 2024, Strona(/y) 1273-1284, ISSN 1863-1703
Wydawca: Springer Verlag
DOI: 10.1007/s11760-023-02821-7

GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol

Autorzy: Gabriele Ruffolo, Alessandro Gaeta, Beatrice Cannata, Camilla Pinzaglia, Eleonora Aronica, Alessandra Morano, Pierangelo Cifelli, Eleonora Palma
Opublikowane w: Life, Numer 12, 2024, Strona(/y) 2042, ISSN 2075-1729
Wydawca: MDPI
DOI: 10.3390/life12122042

Advances in the genetics and neuropathology of tuberous sclerosis complex: edging closer to targeted therapy

Autorzy: Paolo Curatolo, Nicola Specchio, Eleonora Aronica
Opublikowane w: The Lancet Neurology, Numer 21, 2023, Strona(/y) 843-856, ISSN 1474-4422
Wydawca: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(22)00213-7

Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period

Autorzy: Anatoly Korotkov; Mark J. Luinenburg; Alessia Romagnolo; Till S. Zimmer; Jackelien van Scheppingen; Anika Bongaarts; Diede W.M. Broekaart; Jasper J. Anink; Caroline Mijnsbergen; Floor E. Jansen; Wim van Hecke; Wim G. M. Spliet; Peter C. van Rijen; Martha Feucht; Johannes A. Hainfellner; Pavel Krsek; Josef Zamecnik; Peter B. Crino; Katarzyna Kotulska; Lieven Lagae; Anna C. Jansen; David J. Kwiatkow
Opublikowane w: Journal of Neurodevelopmental isorders, 2021, ISSN 1866-1947
Wydawca: Springer Verlag
DOI: 10.1186/s11689-022-09416-2

Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

Autorzy: Diogo M. Lourenço, Rita Soares, Sónia Sá-Santos, Joana M. Mateus, Rui S. Rodrigues, João B. Moreira, Sandra H. Vaz, Ana M. Sebastião, Susana Solá, Sara Xapelli
Opublikowane w: European Journal of Pharmacology, Numer 959, 2024, Strona(/y) 176079, ISSN 0014-2999
Wydawca: Elsevier BV
DOI: 10.1016/j.ejphar.2023.176079

Generalized Fast Discharges Along the Genetic Generalized Epilepsy Spectrum: Clinical and Prognostic Significance.

Autorzy: Placidi, Anna Teresa Giallonardo, Francesca Izzi and Carlo Di Bonaventura
Opublikowane w: rontiers in Neurology, 2022, ISSN 1664-2295
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.844674

Cognitive comorbidities of experimental absence seizures are independent of anxiety

Autorzy: Mariana Neuparth-Sottomayor, Carolina C. Pina, Tatiana P. Morais, Miguel Farinha-Ferreira, Daniela Sofia Abreu, Filipa Solano, Francisco Mouro, Mark Good, Ana Maria Sebastião, Giuseppe Di Giovanni, Vincenzo Crunelli, Sandra H. Vaz
Opublikowane w: Neurobiology of Disease, Numer 186, 2023, Strona(/y) 106275, ISSN 0969-9961
Wydawca: Academic Press
DOI: 10.1016/j.nbd.2023.106275

Regulation of hippocampal postnatal and adult neurogenesis by adenosine A2A receptor: Interaction with brain-derived neurotrophic factor

Autorzy: Filipa F Ribeiro, Filipa Ferreira, Rui S Rodrigues, Rita Soares, Diogo M Pedro, Marta Duarte-Samartinho, Rita I Aroeira, Elisabete Ferreiro, Jorge Valero, Susana Solá, Helena Mira, Ana M Sebastião, Sara Xapelli
Opublikowane w: Stem Cells, 2021, ISSN 1066-5099
Wydawca: AlphaMed Press Inc
DOI: 10.1002/stem.3421

Loss of maturity and homeostatic functions in Tuberous Sclerosis Complex-derived astrocytes

Autorzy: Mark J. Luinenburg, Mirte Scheper, Frederik N. F. Sørensen, Jasper J. Anink, Wim Van Hecke, Irina Korshunova, Floor E. Jansen, Kate Riney, Pieter van Eijsden, Peter Gosselaar, James D. Mills, Rozemarijn S. Kalf, Till S. Zimmer, Diede W. M. Broekaart, Konstantin Khodosevich, Eleonora Aronica, Angelika Mühlebner
Opublikowane w: Frontiers in Cellular Neuroscience, Numer 17, 2023, ISSN 1662-5102
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncel.2023.1284394

Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex

Autorzy: • Anika Bongaarts, Caroline Mijnsbergen, Jasper J. Anink, Floor E. Jansen, Wim G.M. Spliet, Wilfred F.A. den Dunnen, Roland Coras, Ingmar Blümcke, Werner Paulus, Victoria E. Gruber, Theresa Scholl, Johannes A. Hainfellner, Martha Feucht, Katarzyna Kotulska, Sergiusz Jozwiak, Wieslawa Grajkowska, Anna Maria Buccoliero, Chiara Caporalini, Flavio Giordano, Lorenzo Genitori, Figen Söylemezoğlu, J
Opublikowane w: Cellular and Molecular Neurobiology, 2021, ISSN 0272-4340
Wydawca: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10571-021-01157-5

Adenosinergic System and BDNF Signaling Changes as a Cross-Sectional Feature of RTT: Characterization of Mecp2 Heterozygous Mouse Females

Autorzy: Catarina Miranda-Lourenço, Jéssica Rosa, Nádia Rei, Rita F. Belo, Ana Luísa Lopes, Diogo Silva, Cátia Vieira, Teresa Magalhães-Cardoso, Ricardo Viais, Paulo Correia-de-Sá, Ana M. Sebastião, Maria J. Diógenes
Opublikowane w: International Journal of Molecular Sciences, Numer 24, 2023, Strona(/y) 16249, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242216249

Of adenosine and the blues: The adenosinergic system in the pathophysiology and treatment of major depressive disorder.

Autorzy: Joana Gomes; Miguel Farinha-Ferreira; Nádia Rei; Joana Gonçalves-Ribeiro; Joaquim A. Ribeiro; Ana M. Sebastião; Sandra H. Vaz
Opublikowane w: Pharmacological Research, Numer Volume 163, January 2021, 105363, 2020, ISSN 1043-6618
Wydawca: Academic Press
DOI: 10.1016/j.phrs.2020.105363

Traditional and Innovative Anti-seizure Medications Targeting Key PhysiopathologicalMechanisms: Focus on Neurodevelopment and Neurodegeneration

Autorzy: Miriam Sciaccaluga, Gabriele Ruffolo, Eleonora Palma, Cinzia Costa
Opublikowane w: Current Neuropharmacology, Numer 21, 2023, Strona(/y) 1736-1754, ISSN 1570-159X
Wydawca: Bentham Science Publishers
DOI: 10.2174/1570159x21666230504160948

Balloon cells promote immune system activation in focal cortical dysplasia type 2b.

Autorzy: Till S. Zimmer; Diede W. M. Broekaart; Mark J. Luinenburg; Caroline Mijnsbergen; Jasper J. Anink; Nam Suk Sim; Iliana Michailidou; Floor E. Jansen; Peter C. van Rijen; Jeong Ho Lee; Liesbeth François; Jonathan van Eyll; Stefanie Dedeurwaerdere; Stefanie Dedeurwaerdere; Erwin A. van Vliet; Angelika Mühlebner; Angelika Mühlebner; James D. Mills; Eleonora Aronica
Opublikowane w: Neuropathology and Applied Neurobiology, Numer 39, 2021, ISSN 1365-2990
Wydawca: Wiley Online Library
DOI: 10.1111/nan.12736

Astroglial calcium signaling and homeostasis in tuberous sclerosis complex

Autorzy: Alessia Romagnolo, Giulia Dematteis, Mirte Scheper, Mark J. Luinenburg, Angelika Mühlebner, Wim Van Hecke, Marcello Manfredi, Veronica De Giorgis, Simone Reano, Nicoletta Filigheddu, Valeria Bortolotto, Laura Tapella, Jasper J. Anink, Liesbeth François, Stefanie Dedeurwaerdere, James D. Mills, Armando A. Genazzani, Dmitry Lim, Eleonora Aronica
Opublikowane w: Acta Neuropathologica, Numer 147, 2024, ISSN 0001-6322
Wydawca: Springer Verlag
DOI: 10.1007/s00401-024-02711-3

Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress

Autorzy: Till S. Zimmer, Anatoly Korotkov, Susan Zwakenberg, Floor E. Jansen, Fried J. T. Zwartkruis, Nicholas R. Rensing, Michael Wong, Angelika Mühlebner, Erwin A. van Vliet, Eleonora Aronica, James D. Mills
Opublikowane w: Brain Pathology, 2021, ISSN 1750-3639
Wydawca: Wiley Online Library
DOI: 10.1111/bpa.12949

High Caloric Diet Induces Memory Impairment and Disrupts Synaptic Plasticity in Aged Rats

Autorzy: Sara L. Paulo; Catarina Miranda-Lourenço; Rita F. Belo; Rui S. Rodrigues; João Fonseca-Gomes; Sara R. Tanqueiro; Vera Geraldes; Isabel Rocha; Ana M. Sebastião; Sara Xapelli; Maria J. Diógenes
Opublikowane w: Current Numers in Molecular Biology, Vol 43, Iss 162, Pp 2305-2319 (2021), Numer 9, 2021, ISSN 1467-3045
Wydawca: MDPI
DOI: 10.3390/cimb43030162

GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β

Autorzy: Gabriele Ruffolo, Veronica Alfano, Alessia Romagnolo, Till Zimmer, James D. Mills, Pierangelo Cifelli, Alessandro Gaeta, Alessandra Morano, Jasper Anink, Angelika Mühlebner, Annamaria Vezzani, Eleonora Aronica, Eleonora Palma
Opublikowane w: Scientific Reports, Numer 12, 2023, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-22806-9

Communication defects with astroglia contribute to early impairments in the motor cortex plasticity of SOD1G93A mice

Autorzy: Sara Costa-Pinto, Joana Gonçalves-Ribeiro, Joana Tedim-Moreira, Renato Socodato, João B. Relvas, Ana M. Sebastião, Sandra H. Vaz
Opublikowane w: Neurobiology of Disease, Numer 193, 2024, Strona(/y) 106435, ISSN 0969-9961
Wydawca: Academic Press
DOI: 10.1016/j.nbd.2024.106435

Unmoving and uninflamed: Characterizing neuroinflammatory dysfunction in the Wistar‐Kyoto rat model of depression

Autorzy: Miguel Farinha‐Ferreira, Daniela M. Magalhães, Mariana Neuparth‐Sottomayor, Hugo Rafael, Catarina Miranda‐Lourenço, Ana M. Sebastião
Opublikowane w: Journal of Neurochemistry, 2024, ISSN 0022-3042
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jnc.16083

Sustained NMDA receptor hypofunction impairs brain-derived neurotropic factor signalling in the PFC, but not in the hippocampus, and disturbs PFC-dependent cognition in mice

Autorzy: Sara R Tanqueiro, Francisco M Mouro, Catarina B Ferreira, Céline F Freitas, João Fonseca-Gomes, Frederico Simões do Couto, Ana M Sebastião, Neil Dawson, Maria J Diógenes
Opublikowane w: Journal of Psychopharmacology, Numer 35, 2021, Strona(/y) 730-743, ISSN 0269-8811
Wydawca: SAGE Publications
DOI: 10.1177/02698811211008560

The sphingosine 1‐phosphate analogue, <scp>FTY720</scp>, modulates the lipidomic signature of the mouse hippocampus

Autorzy: Daniela M. Magalhães, Nicolas A. Stewart, Myrthe Mampay, Sara O. Rolle, Chloe M. Hall, Emad Moeendarbary, Melanie S. Flint, Ana M. Sebastião, Cláudia A. Valente, Marcus K. Dymond, Graham K. Sheridan
Opublikowane w: Journal of Neurochemistry, Numer 168, 2024, Strona(/y) 1113-1142, ISSN 0022-3042
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jnc.16073

Functional Gastrointestinal Disorders in Patients With Epilepsy: Reciprocal Influence and Impact on Seizure Occurrence.

Autorzy: Federica Avorio; Federica Avorio; Emanuele Cerulli Irelli; Alessandra Morano; Martina Fanella; Biagio Orlando; Mariarita Albini; Luca M. Basili; Gabriele Ruffolo; Jinane Fattouch; Mario Manfredi; Emilio Russo; Pasquale Striano; Marilia Carabotti; Anna Teresa Giallonardo; Carola Severi; Carlo Di Bonaventura
Opublikowane w: Frontiers in Neurology, Vol 12 (2021), Numer 23, 2021, ISSN 1664-2295
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fneur.2021.705126

Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity

Autorzy: Stefania Scalise, Clara Zannino, Valeria Lucchino, Michela Lo Conte, Luana Scaramuzzino, Pierangelo Cifelli, Tiziano D’Andrea, Katiuscia Martinello, Sergio Fucile, Eleonora Palma, Antonio Gambardella, Gabriele Ruffolo, Giovanni Cuda, Elvira Immacolata Parrotta
Opublikowane w: Biomedicines, Numer 10, 2024, Strona(/y) 1075, ISSN 2227-9059
Wydawca: Frontiers
DOI: 10.3390/biomedicines10051075

Autorzy: Daniela M. Magalhães, Myrthe Mampay, Ana M. Sebastião, Graham K. Sheridan, Cláudia A. Valente
Opublikowane w: Neurochemistry International, Numer 174, 2024, Strona(/y) 105678, ISSN 0197-0186
Wydawca: Elsevier BV
DOI: 10.1016/j.neuint.2024.105678

Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior

Autorzy: Miguel Farinha-Ferreira, Nádia Rei, João Fonseca-Gomes, Catarina Miranda-Lourenço, Paula Serrão, Sandra H. Vaz, Joana I. Gomes, Valéria Martins, Beatriz de Alves Pereira, Ana M. Sebastião
Opublikowane w: Neuropharmacology, Numer 214, 2023, Strona(/y) 109155, ISSN 0028-3908
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2022.109155

Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging

Autorzy: Erwin A van Vliet, Nicola Marchi.
Opublikowane w: Epilepsy, 2022, ISSN 1528-1167
Wydawca: Wiley Online Library
DOI: 10.1111/epi.17210

Neuroprotective effects of platinum nanoparticle-based microreactors in bicuculline-induced seizures

Autorzy: Roberto N. Oliveira, Patrícia S. Carvalhinho-Lopes, Carolina P.F. Carvalho, Rafael Y.S. Hirata, Sandra H. Vaz, Ana Maria Sebastião, Adam Armada-Moreira, Bárbara A. Rosário, Jéssica A. Lemes, Beatriz Soares-Silva, José S. de Andrade, José Ronaldo Santos, Alessandra M. Ribeiro, Milena B. Viana
Opublikowane w: Behavioural Brain Research, Numer 465, 2024, Strona(/y) 114956, ISSN 0166-4328
Wydawca: Elsevier BV
DOI: 10.1016/j.bbr.2024.114956

Editorial: Cellular and molecular targets in epileptogenesis focusing on disease prevention

Autorzy: Diana Cunha-Reis, Sandra Henriques Vaz, Paulo Correia-de-Sá
Opublikowane w: Frontiers in Cellular Neuroscience, Numer 17, 2023, ISSN 1662-5102
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncel.2023.1251038

Microglia Depletion from Primary Glial Cultures Enables to Accurately Address the Immune Response of Astrocytes

Autorzy: Mariana Van Zeller, Ana M. Sebastião, Cláudia A. Valente
Opublikowane w: Biomolecules, Numer 12, 2024, Strona(/y) 666, ISSN 2218-273X
Wydawca: MDPI
DOI: 10.3390/biom12050666

A maestro role of adenosine A

Autorzy: Sebastião, Ana M.
Opublikowane w: Purinergic Signal, Numer 6, 2022
Wydawca: Purinergic signalling

Astrocytes in Amyotrophic Lateral Sclerosis

Autorzy: Sandra H. Vaz, Sara Pinto, Ana M. Sebastião, and Dora Brites.
Opublikowane w: Amyotrophic Lateral Sclerosis., 2021, ISBN 978-0-6450017-7-8
Wydawca: Exon Publications
DOI: 10.36255/exonpublications.amyotrophiclateralsclerosis.astrocytes.2021

An Overview of Adult Neurogenesis

Autorzy: Filipa F. Ribeiro, Sara Xapelli
Opublikowane w: Advances in Experimental Medicine and Biology, Recent Advances in NGF and Related Molecules, 2021, Strona(/y) 77-94
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-030-74046-7_7

Intervention of Brain-Derived Neurotrophic Factor and Other Neurotrophins in Adult Neurogenesis

Autorzy: Filipa F. Ribeiro, Sara Xapelli
Opublikowane w: Advances in Experimental Medicine and Biology, Recent Advances in NGF and Related Molecules, 2021, Strona(/y) 95-115
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-030-74046-7_8

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