Serotonin and BEYOND: Brain development research Excelling Young Ones in Neurotechnologies and Discoveries

Informacje na temat projektu

SEROTONIN and BEYOND

Identyfikator umowy o grant: 953327

DOI

10.3030/953327

Projekt został zamknięty

Data podpisania przez KE 28 Sierpnia 2020

Data rozpoczęcia 1 Stycznia 2021

Data zakończenia 30 Kwietnia 2025

Finansowanie w ramach

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Koszt całkowity

€ 4 012 551,00

Wkład UE

€ 4 012 551,00

Koordynowany przez

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Netherlands

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Websites, patent fillings, videos etc. (1)

Website with advertised positions

Other (2)

Corporate Identity (Logo and Templates)
Press releases

Press releases, M24, 48

Publikacje

Peer reviewed articles (28)

No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Autorzy: S. E. P. Bruzzone, B. Ozenne, P. M. Fisher, G. Ortega, P. S. Jensen, V. H. Dam, C. Svarer, G. M. Knudsen, K. P. Lesch, V. G. Frokjaer
Opublikowane w: Clinical Epigenetics, Numer 16, 2024, ISSN 1868-7083
Wydawca: Springer/Nature
DOI: 10.1186/s13148-024-01678-y

Carbon-mixed dental cement for fixing fiber optic ferrules prevents visuallytriggered locomotive enhancement in mice upon optogenetic stimulation

Autorzy: N. Araragi, N. Alenina, M. Bader
Opublikowane w: Heliyon, Numer 8, 2022, Strona(/y) e08692, ISSN 2405-8440
Wydawca: Cell press
DOI: 10.1016/j.heliyon.2021.e08692

Genetic contributions to brain serotonin transporter levels in healthy adults

Autorzy: Silvia Elisabetta Portis Bruzzone; Arafat Nasser; Sagar Sanjay Aripaka; Marie Spies; Brice Ozenne; Peter Steen Jensen; Gitte Moos Knudsen; Vibe Gedsoe Frokjaer; Patrick MacDonald Fisher
Opublikowane w: Scientific Reports, Numer v 13, 2023, Strona(/y) no 16426, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-023-43690-x

Wiring and Volume Transmission: An Overview of the Dual Modality for Serotonin Neurotransmission

Autorzy: Giulia Gianni, Massimo Pasqualetti
Opublikowane w: ACS Chemical Neuroscience, Numer 14, 2023, Strona(/y) 4093-4104, ISSN 1948-7193
Wydawca: American Chemical Society
DOI: 10.1021/acschemneuro.3c00648

Alterations of mitochondrial dynamics in serotonin transporter knockout rats: A possible role in the fear extinction recall mechanisms.

Autorzy: Paola, Brivio; Maria Teresa, Gallo; Peter, Karel; Giulia, Cogi; Fabio, Fumagalli; Judith R, Homberg; Francesca, Calabrese
Opublikowane w: Frontiers in Behavioral Neuroscience, Numer Vol 16, 2022, Strona(/y) 957702, ISSN 1662-4548
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnbeh.2022.957702

Perinatal serotonin signalling dynamically influences the development of cortical GABAergic circuits with consequences for lifelong sensory encoding

Autorzy: Gabriel Ocana-Santero, Hannah Warming, Veronica Munday, Heather A. MacKay, Caius Gibeily, Christopher Hemingway, Jacqueline A. Stacey, Abhishek Saha, Ivan P. Lazarte, Anjali Bachetta, Fei Deng, Yulong Li, Adam M. Packer, Trevor Sharp, Simon. J. B. Butt
Opublikowane w: Nature Communications, Numer 16, 2025, Strona(/y) 5203, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-025-59659-5

Haploinsufficiency of the Attention-Deficit/Hyperactivity Disorder Risk Gene St3gal3 in Mice Causes Alterations in Cognition and Expression of Genes Involved in Myelination and Sialylation

Autorzy: Olga Rivero; Olga Rivero; Judit Alhama-Riba; Hsing-Ping Ku; Matthias Fischer; Gabriela Ortega; Péter Álmos; David Diouf; Daniel van den Hove; Klaus-Peter Lesch; Klaus-Peter Lesch; Klaus-Peter Lesch
Opublikowane w: Frontiers in Genetics, Numer Vol 12, 2021, Strona(/y) article 668488, ISSN 1664-8021
Wydawca: Frontiers Media
DOI: 10.3389/fgene.2021.688488

Peripheral Serotonin Deficiency Affects Anxiety-like Behavior and the Molecular Response to an Acute Challenge in Rats

Autorzy: Giulia Sbrini, Sabrina I. Hanswijk, Paola Brivio, Anthonieke Middelman, Michael Bader Fabio Fumagalli, Natalia Alenina, Judith R. Homberg and Francesca Calabrese
Opublikowane w: International Journal of Molecular Sciences, Numer 23, 2022, Strona(/y) 4941, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23094941

Perinatal Maternal Depressive Symptoms and Brain Connectivity Among 9- to 15-Year-Old Offspring

Autorzy: Dogukan Koc, Adriana P. C. Hermans, Bing Xu, Ryan L. Muetzel, Hanan El Marroun, Henning Tiemeier
Opublikowane w: JAMA Network Open, Numer 8, 2025, Strona(/y) e2523978, ISSN 2574-3805
Wydawca: American Medical Association (AMA)
DOI: 10.1001/jamanetworkopen.2025.23978

SSRIs in Pregnancy—What Offspring Brain Volumes Can and Cannot Tell Us—Reply

Autorzy: Dogukan Koc, Henning Tiemeier, Hanan El Marroun
Opublikowane w: JAMA Psychiatry, Numer 81, 2024, Strona(/y) 317, ISSN 2168-622X
Wydawca: American Medical Association
DOI: 10.1001/jamapsychiatry.2023.5039

Effects of an Oral Contraceptive on Dynamic Brain States and Network Modularity in a Serial Single-Subject Study

Autorzy: K.H.R. Jensen, D.E. McCulloch, A.S. Olsen, S.E.P. Bruzzone, S. V. Larsen, P.M. Fisher, V.G. Frokjaer
Opublikowane w: Frontiers in Neuroscience, Numer 16, 2022, Strona(/y) 855582, ISSN 1662-4548
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnins.2022.855582

DNA methylation of serotonin genes as predictive biomarkers of antidepressant treatment response

Autorzy: Silvia Elisabetta Portis Bruzzone, Brice Ozenne, Patrick MacDonald Fisher, Gabriela Ortega, Martin Balslev Jørgensen, Gitte Moos Knudsen, Klaus-Peter Lesch, Vibe Gedsoe Frokjaer
Opublikowane w: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Numer 136, 2025, Strona(/y) 111160, ISSN 0278-5846
Wydawca: Elsevier BV
DOI: 10.1016/j.pnpbp.2024.111160

Prenatal Antidepressant Exposure and Offspring Brain Morphologic Trajectory

Autorzy: Dogukan Koc, Henning Tiemeier, MD, Bruno H. Stricker, Ryan L. Muetzel, Manon Hillegers, Hanan El Marroun.
Opublikowane w: JAMA Psychiatry, Numer August 30, 2023, 2023, ISSN 2168-622X
Wydawca: American Medical Association
DOI: 10.1001/jamapsychiatry.2023.3161

Not Just a Mood Disorder─Is Depression a Neurodevelopmental, Cognitive Disorder? Focus on Prefronto-Thalamic Circuits

Autorzy: Nina Nitzan Soto, Patricia Gaspar, Alberto Bacci
Opublikowane w: ACS Chemical Neuroscience, Numer 15, 2024, Strona(/y) 1611-1618, ISSN 1948-7193
Wydawca: American Chemical Society
DOI: 10.1021/acschemneuro.3c00828

Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice

Autorzy: Yunqing Cao, Oliver Popp, Niccolo Milani, Fatimunnisa Qadri, Ralf Kühn, Philipp Mertins, Michael Bader, Natalia Alenina
Opublikowane w: Communications Biology, Numer 7, 2024, Strona(/y) 1641, ISSN 2399-3642
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-07360-6

Tryptophan Hydroxylase-2-Mediated Serotonin Biosynthesis Suppresses Cell Reprogramming into Pluripotent State

Autorzy: Sergey A. Sinenko, Andrey A. Kuzmin, Elena V. Skvortsova, Sergey V. Ponomartsev, Evgeniya V. Efimova, Michael Bader, Natalia Alenina and Alexey N. Tomilin
Opublikowane w: International Journal of Molecular Sciences, Numer 24, 2023, Strona(/y) 4862, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24054862

Associations of serotonin-related brain morphology in early adolescence with behavioral and emotional problems

Autorzy: Dogukan Koc, Martin Nørgaard, Melanie Ganz, Ryan L. Muetzel, Hanan El Marroun, Henning Tiemeier, Vibe G. Frokjaer
Opublikowane w: NeuroImage: Clinical, Numer 48, 2025, Strona(/y) 103851, ISSN 2213-1582
Wydawca: Elsevier BV
DOI: 10.1016/j.nicl.2025.103851

Impact of Serotonin Deficiency on Circadian Dopaminergic Rhythms

Autorzy: Giacomo Maddaloni, Noemi Barsotti, Sara Migliarini, Martina Giordano, Serena Nazzi, Marta Picchi, Francesco Errico, Alessandro Usiello, Massimo Pasqualetti
Opublikowane w: International Journal of Molecular Sciences, Numer 25, 2025, Strona(/y) 6475, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25126475

Understanding the Role of Oxidative Stress, Neuroinflammation and Abnormal Myelination in Excessive Aggression Associated with Depression: Recent Input from Mechanistic Studies

Autorzy: Anna Gorlova; Evgeniy Svirin; Dmitrii Pavlov; Raymond Cespuglio; Andrey Proshin; Careen A. Schroeter; Klaus-Peter Lesch; Tatyana Strekalova
Opublikowane w: Int. J. Mol. Sci., Numer Vol 24, 2023, Strona(/y) 915, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24020915

Reclaiming saliency: Rhythmic precision-modulated action and perception.

Autorzy: Anil Meera, A., Novicky, F., Parr, T., Friston, K., Lanillos, P., & Sajid, N.
Opublikowane w: Frontiers in Neurorobotics, Numer Volume 16 - 2022, 2022, ISSN 1662-5218
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnbot.2022.896229

Serotonin limits generation of chromaffin cells during adrenal organ development

Autorzy: Polina Kameneva, Victoria I. Melnikova, Maria Eleni Kastriti, Anastasia Kurtova, Emil Kryukov, Aliia Murtazina, Louis Faure, Irina Poverennaya, Artem V. Artemov, Tatiana S. Kalinina, Nikita V. Kudryashov, Michael Bader, Jan Skoda, Petr Chlapek, Lucie Curylova, Lukas Sourada, Jakub Neradil, Marketa Tesarova, Massimo Pasqualetti, Patricia Gaspar, Vasily D. Yakushov, Boris I. Sheftel, Tomas Zikmund,
Opublikowane w: Nature Communications, Numer 13, 2022, Strona(/y) 2901, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-30438-w

Intrauterine Exposure to Antidepressants or Maternal Depressive Symptoms and Offspring Brain White Matter Trajectories From Late Childhood to Adolescence

Autorzy: Dogukan Koc, Hanan El Marroun, Bruno H. Stricker, Ryan L. Muetzel, Henning Tiemeier
Opublikowane w: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Numer 9, 2024, Strona(/y) 217-226, ISSN 2451-9022
Wydawca: Elsevier BV
DOI: 10.1016/j.bpsc.2023.10.009

Constitutive depletion of brain serotonin differentially affects rats’ social and cognitiveabilities

Autorzy: L. Alonso, P. Peeva, S. Stasko, M. Bader, N. Alenina, Y. Winter, M. Rivalan
Opublikowane w: iScience, Numer 26, 2023, Strona(/y) 105998, ISSN 2589-0042
Wydawca: Cell Press Elsevier Inc.
DOI: 10.1016/j.isci.2023.105998

<i>In Vivo</i> Two-Photon Microscopy Reveals Sensory-Evoked Serotonin (5-HT) Release in Adult Mammalian Neocortex

Autorzy: Gabriel Ocana-Santero, Adam M. Packer, Trevor Sharp, Simon J. B. Butt
Opublikowane w: ACS Chemical Neuroscience, Numer 15, 2024, Strona(/y) 456-461, ISSN 1948-7193
Wydawca: American Chemical Society
DOI: 10.1021/acschemneuro.3c00725

Generation of a ST3GAL3 null mutant induced pluripotent stem cell (iPSC)line (UKWMPi002-A-3) by CRISPR/Cas9 genome editing

Autorzy: D. Diouf, M.R. Vitale, J.E.M Zoller, A.-M. Pineau, E. Klopocki, C. Hamann, G.C. Ziegler, T. Vanmierlo, D. van den Hove, K.-P. Lesch
Opublikowane w: Stemm Cell Research, Numer Vol 63, 2023, Strona(/y) 103038, ISSN 1873-5061
Wydawca: Elsevier
DOI: 10.1016/j.scr.2023.103038

Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits

Autorzy: Tianhua Wang, Judith R. Homberg, Laura Boreggio, Marta C. F. Samina, Rogério C. R. Castro, Sharon M. Kolk, Natalia Alenina, Michael Bader, Jinye Dai, Markus Wöhr
Opublikowane w: Molecular Autism, Numer 15, 2024, Strona(/y) 50, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-024-00629-x

Alterations of Adult Prefrontal Circuits Induced by Early Postnatal Fluoxetine Treatment Mediated by 5-HT7 Receptors

Autorzy: Angela Michela De Stasi, Javier Zorrilla de San Martin, Nina Soto, Andrea Aguirre, Jimmy Olusakin, Joana Lourenço, Patricia Gaspar, Alberto Bacci
Opublikowane w: The Journal of Neuroscience, Numer 45, 2025, Strona(/y) e2393232024, ISSN 0270-6474
Wydawca: Society for Neuroscience
DOI: 10.1523/jneurosci.2393-23.2024

Tph2 Gene Expression Defines Ethanol Drinking Behavior in Mice

Autorzy: Magdalena Zaniewska, Valentina Mosienko, Michael Bader, and Natalia Alenina
Opublikowane w: Cells, Numer 11, 2022, Strona(/y) 874, ISSN 2073-4409
Wydawca: MDPI
DOI: 10.3390/cells11050874

Non-peer reviewed articles (1)

Maternal tryptophan hydroxylase 1 genotype defines offspring’s cognition and behaviour

Autorzy: R. Rocha De Castro, M. Verheij, A.A. Vazquez, J. Buitelaar, J. Homberg
Opublikowane w: Neuroscience Applied, Numer 2, 2024, Strona(/y) 102608, ISSN 2772-4085
Wydawca: Elsevier BV
DOI: 10.1016/j.nsa.2023.102608

Book chapters (1)

Robotic Active Tactile Sensing Inspired by Serotonergic Modulation Using Active Inference

Autorzy: Filip Novicky, Joshua Offergeld, Simon Janssen, Pablo Lanillos
Opublikowane w: Lecture Notes in Computer Science, Biomimetic and Biohybrid Systems, 2023, Strona(/y) 33-55
Wydawca: Springer Nature Switzerland
DOI: 10.1007/978-3-031-38857-6_3