Coherent Raman Imaging for the Molecular Study of the OrigiN of diseases

Informacje na temat projektu

CRIMSON

Identyfikator umowy o grant: 101016923

DOI

10.3030/101016923

Projekt został zamknięty

Data podpisania przez KE 30 Listopada 2020

Data rozpoczęcia 1 Grudnia 2020

Data zakończenia 31 Maja 2024

Finansowanie w ramach

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)

Koszt całkowity

€ 5 132 801,25

Wkład UE

€ 5 132 801,25

Koordynowany przez

POLITECNICO DI MILANO
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (1)

D5.3 Report on performed communication, dissemination and exploitation activities

Report on performed communication, dissemination and exploitation activities

Open Research Data Pilot (1)

D6.1 Data Management Plan

Data Management Plan

Websites, patent fillings, videos etc. (4)

D5.4 Preliminary communication kit

Preliminary communication kit that will be updated throughout the project

D5.5 Communication kit (final)

Communication kit in final version.

D5.1 Project website, graphical identity of the CRIMSON project, project flyer and database of stakeholders

Project website graphical identity of the CRIMSON project project flyer and database of stakeholders

D5.5 Communication kit (mid-term)

Communication kit updated at M18

Publikacje

Peer reviewed articles (32)

Comparing Transmission- and Epi-BCARS: A Transnational Round Robin on Solid State Materials

Autorzy: Hempel, Franz; Vernuccio, Federico; König, Lukas; Buschbeck, Robin; Rüsing, Michael; Cerullo, Giulio; Polli, Dario; Eng, Lukas M.
Opublikowane w: Applied Optics, Numer Vol. 63, Numer 1, 2024, Strona(/y) 112-121, ISSN 1559-128X
Wydawca: Optica
DOI: 10.48550/arxiv.2306.09701

Sulfatide imaging identifies tumor cells in colorectal cancer peritoneal metastases

Autorzy: G. M. Sarcinelli, L. Varinelli, S. Ghislanzoni, F. Padelli, D. Lorenzini, A. Vingiani, M. Milione, M. Guaglio, S. Kusamura, M. Deraco, G. Pruneri, M. Gariboldi, D. Baratti, I. Bongarzone
Opublikowane w: Cancer & Metabolism, Numer 12, 2024, Strona(/y) 13, ISSN 2049-3002
Wydawca: BioMed Central Ltd, part of Springer Nature
DOI: 10.1186/s40170-024-00345-3

Feasibility studies of multimodal nonlinear endoscopy using multicore fiber bundles for remote scanning from tissue sections to bulk organs

Autorzy: Hyeonsoo Bae, Marko Rodewald, Tobias Meyer-Zedler, Thomas W. Bocklitz, Gregor Matz, Bernhard Messerschmidt, Adrian T. Press, Michael Bauer, Orlando Guntinas-Lichius, Andreas Stallmach, Michael Schmitt & Juergen Popp
Opublikowane w: Scientific Reports volume 13, Article number: 13779, Numer Scientific Reports volume 13, Article number: 13779, 2023, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-023-40944-6

Coherent Stokes Raman scattering microscopy (CSRS)

Autorzy: Sandro Heuke, Hervé Rigneault
Opublikowane w: Nature Communications, Numer 14, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-38941-4

Deep Ensemble Learning and Transfer Learning Methods for Classification of Senescent Cells from Nonlinear Optical Microscopy Images

Autorzy: Salvatore Sorrentino, Francesco Manetti, Arianna Bresci, Federico Vernuccio, Chiara Ceconello, Silvia Ghislanzoni, Italia Bongarzone, Renzo Vanna, Giulio Cerullo, Dario Polli
Opublikowane w: Front. Chem., Numer 11, 1213981, 2023, ISSN 2296-2646
Wydawca: Frontiers
DOI: 10.3389/fchem.2023.1213981

Noninvasive morpho-molecular imaging reveals early therapy-induced senescence in human cancer cells

Autorzy: Arianna Bresci, Jeong Hee Kim, Silvia Ghislanzoni, Francesco Manetti, Lintong Wu, Federico Vernuccio, Chiara Ceconello, Salvatore Sorrentino, Ishan Barman, Italia Bongarzone, Giulio Cerullo, Renzo Vanna, And Dario Polli
Opublikowane w: Science Advances, Numer 9, eadg6231, 2023, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adg6231

Reduced sulfatide content in deferoxamine-induced senescent HepG2 cells

Autorzy: Silvia Ghislanzoni, Gaia Martina Sarcinelli, Arianna Bresci, Francesco Manetti, Dario Polli, Antonella Tomassetti, Maria Teresa Radice, Italia Bongarzone
Opublikowane w: Int J Biochem Cell Biol ., Numer Vol. 159, 2023, ISSN 1357-2725
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.biocel.2023.106419

Full-Spectrum CARS Microscopy of Cells and Tissues with Ultrashort White-Light Continuum Pulses

Autorzy: Federico Vernuccio, Renzo Vanna, Chiara Ceconello, Arianna Bresci, Francesco Manetti, Salvatore Sorrentino, Silvia Ghislanzoni, Flavia ambertucci, Omar Motiño, Isabelle Martins, Guido Kroemer, Italia Bongarzone, Giulio Cerullo, and Dario Polli
Opublikowane w: J. Phys. Chem., Numer B 127, 21, 2023, Strona(/y) 4733–4745, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpcb.3c01443

Experimental determination of shift-less aberration bases for sensorless adaptive optics in nonlinear microscopy

Autorzy: Benedetta Talone; Paolo Pozzi; Miriam Cavagnini; Dario Polli; Gianluca Pozzi; Jonathan Mapelli
Opublikowane w: Optics Express, Numer 29, 2021, Strona(/y) 37617-37627, ISSN 2334-2536
Wydawca: Optica
DOI: 10.1364/oe.435262

Selective Detection in Impulsive Low-Frequency Raman Imaging Using Shaped Probe Pulses

Autorzy: Siddarth Shivkumar, Dekel Ranann, Samuel Metais, Sisira Suresh, Nicolas Forget, Randy Bartels, Dan Oron, and Hervé Rigneault
Opublikowane w: Phys. Rev. Applied, Numer 19, 2023, ISSN 2643-1564
Wydawca: American Physical Society
DOI: 10.1103/physrevapplied.19.054075

Label-free multimodal nonlinear optical microscopy reveals features of bone composition in pathophysiological conditions

Autorzy: Benedetta Talone, Arianna Bresci, Francesco Manetti, Federico Vernuccio, Alejandro De La Cadena, Chiara Ceconello, Maria L. Schiavone, Stefano Mantero, Ciro Menale, Renzo Vanna, Giulio Cerullo, Cristina Sobacchi and Dario Polli
Opublikowane w: Front. Bioeng. Biotechnol., Numer 22, 10:1042680, 2022, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2022.1042680

Design and test of a rigid endomicroscopic system for multimodal imaging and femtosecond laser ablation

Autorzy: Chenting Lai, Matteo Calvarese, Karl Reichwald, Hyeonsoo Bae, Mohammadsadegh Vafaeinezhad, Tobias Meyer-Zedler, Franziska Hoffmann, Anna Mühlig, Tino Eidam, Fabian Stutzki, Bernhard Messerschmidt, Herbert Gross, Michael Schmitt, Orlando Guntinas-Lichius, Jürgen Popp
Opublikowane w: Journal of Biomedical Optics, Numer Vol. 28, Numer 6, 2023, ISSN 1560-2281
Wydawca: SPIE
DOI: 10.1117/1.jbo.28.6.066004

Deep reinforcement learning control of white-light continuum generation

Autorzy: Carlo Michele Valensise; Alessandro Giuseppi; Giulio Cerullo; Dario Polli
Opublikowane w: Optica, Numer 8, 2021, Strona(/y) 239-242, ISSN 2334-2536
Wydawca: Optica
DOI: 10.1364/optica.414634

Ultrafast Spectral Tuning of a Fiber Laser for Time-Encoded Multiplex Coherent Raman Scattering Microscopy

Autorzy: Thomas Gottschall, Tobias Meyer-Zedler, Matthias Eibl, Tom Pfeiffer, Hubertus Hakert, Michael Schmitt, Robert Huber, Andreas Tünnermann, Jens Limpert, Juergen Popp
Opublikowane w:  J. Phys. Chem. B, Numer 127, 11, 2023, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpcb.2c09115

Double-modulations stimulated Raman scattering: how to image up to 16-fold faster

Autorzy: Sandro Heuke, Xavier Audier, Hervé Rigneault
Opublikowane w: Optics Letters, Numer 15; 48(2), 2023, Strona(/y) 423-426, ISSN 2334-2536
Wydawca: Optica
DOI: 10.1364/ol.467514

Photon-noise: Is a single-pixel camera better than point scanning? A signal-to-noise ratio analysis for Hadamard and Cosine positive modulation

Autorzy: Camille Scotté, Frédéric Galland and Hervé Rigneault
Opublikowane w: J. Phys. Photonics, Numer 5, 2023, ISSN 1742-6596
Wydawca: IOP Publishing
DOI: 10.48550/arxiv.2210.01915

Optical Diffraction Tomography and Raman Confocal Microscopy for the Investigation of Vacuoles Associated with Cancer Senescent Engulfing Cells

Autorzy: Silvia Ghislanzoni; Jeon Woong Kang; Arianna Bresci; Andrea Masella; Koseki J. Kobayashi-Kirschvink; Dario Polli; Italia Bongarzone; Peter T. C. So
Opublikowane w: Biosensors, Numer Vol 13, Iss 11, 2023, Strona(/y) 1-15, ISSN 2079-6374
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.20944/preprints202310.0573.v1

Broadband Four-Wave Mixing Enhanced by Plasmonic Surface Lattice Resonance and Localized Surface Plasmon Resonance in an Azimuthally Chirped Grating

Autorzy: Abhik Chakraborty, Parijat Barman, Ankit Kumar Singh, Xiaofei Wu, Denis A. Akimov, Tobias Meyer-Zedler, Stefan Nolte, Carsten Ronning, Michael Schmitt, Jürgen Popp, Jer-Shing Huang
Opublikowane w: Laser & Photonics Reviews, Numer Volume 17, Numer 7, 2023, ISSN 1863-8899
Wydawca: WILEY Online LIBRARY
DOI: 10.1002/lpor.202200958

Broadband stimulated Raman imaging based on multi-channel lock-in detection for spectral histopathology

Autorzy: Alejandro De la Cadena, Federico Vernuccio, Andrea Ragni, Giuseppe Sciortino, Renzo Vanna, Carino Ferrante, Natalia Pediconi, Carlo Valensise, Luca Genchi, Sergey P. Laptenok, Andrea Doni, Marco Erreni, Tullio Scopigno, Carlo Liberale, Giorgio Ferrari, Marco Sampietro, Giulio Cerullo, Dario Polli
Opublikowane w: APL Photonics, Numer 7, 2022, ISSN 2378-0967
Wydawca: APL Photonics
DOI: 10.1063/5.0093946

Removal of cross-phase modulation artifacts in ultrafast pump–probe dynamics by deep learning

Autorzy: A. Bresci; Michele Guizzardi; Carlo Michele Valensise; Fabio Marangi; Francesco Scotognella; Giulio Cerullo; Dario Polli
Opublikowane w: APL Photonics, Numer 6, 2021, Strona(/y) 076104, ISSN 2378-0967
Wydawca: American Institute of Physics (United States)
DOI: 10.1063/5.0057404

Nonlinear Optical Signal Generation Mediated by a Plasmonic Azimuthally Chirped Grating

Autorzy: Parijat Barman, Abhik Chakraborty, Denis A. Akimov, Ankit Kumar Singh, Tobias Meyer-Zedler, Xiaofei Wu, Carsten Ronning, Michael Schmitt, Jürgen Popp*, and Jer-Shing Huan
Opublikowane w: Nano Lett. 2022, 22, 24, 9914–9919, Numer Nano Lett. 2022, 22, 24, 9914–9919, 2022, Strona(/y) 9914–9919, ISSN 1530-6984
Wydawca: American Chemical Society
DOI: 10.1021/acs.nanolett.2c03348

Live Stimulated Raman Histology for the Near-Instant Assessment of Central Nervous System Samples

Autorzy: Romain Appay, Barbara Sarri, Sandro Heuke, Sébastien Boissonneau, Chang Liu, Etienne Dougy, Laurent Daniel, Didier Scavarda, Henry Dufour, Dominique Figarella-Branger, and Hervé Rigneault
Opublikowane w: Physical Chemistry B, Numer 127, 16, 2023, Strona(/y) 3624–3631, ISSN 1463-9076
Wydawca: Royal Society of Chemistry
DOI: 10.1021/acs.jpcb.3c01156

In vivo organoid growth monitoring by stimulated Raman histology

Autorzy: Barbara Sarri, Véronique Chevrier, Flora Poizat, Sandro Heuke, Florence Franchi, Louis De Franqueville, Eddy Traversari, Jean-Philippe Ratone, Fabrice Caillol, Yanis Dahel, Solène Hoibian, Marc Giovannini, Cécile de Chaisemartin, Romain Appay, Géraldine Guasch, Hervé Rigneault
Opublikowane w: npj Imaging, Numer 2, 2024, Strona(/y) 8, ISSN 2948-197X
Wydawca: Nature Partner Journals
DOI: 10.1038/s44303-024-00019-1

Comparison of denoising tools for the reconstruction of nonlinear multimodal images. Biomedical Optics Express

Autorzy: Rola Houhou, Elsie Quansah, Tobias Meyer-Zedler, Michael Schmitt, Franziska Hoffmann, Orlando Guntinas-Lichius, Jürgen Popp, and Thomas Bocklitz
Opublikowane w: Biomedical Optics Express, Numer volume 14 issue 7, 2023, Strona(/y) 3259-3278, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/boe.477384

Phototoxicity induced in living HeLa cells by focused femtosecond laser pulses: a data-driven approach

Autorzy: Benedetta Talone; M. Bazzarelli; Andrea Schirato; F. Dello Vicario; Daniele Viola; Emanuela Jacchetti; M. Bregonzio; Manuela Teresa Raimondi; Giulio Cerullo; Dario Polli
Opublikowane w: Biomed Opt Express, Numer 12, 2021, Strona(/y) 7886-7905, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/boe.441225

Fingerprint multiplex CARS at high speed based on supercontinuum generation in bulk media and deep learning spectral denoising

Autorzy: Federico Vernuccio, Arianna Bresci, Benedetta Talone, Alejandro De la Cadena, Chiara Ceconello, Stefano Mantero, Cristina Sobacchi, Renzo Vanna, Giulio Cerullo, and Dario Polli
Opublikowane w: Optics Express, Numer 30, 2022, ISSN 1094-4087
Wydawca: Optical Society of America
DOI: 10.1364/oe.463032

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Autorzy: Alejandro, De la Cadena; Federico, Vernuccio; Benedetta, Talone; Arianna, Bresci; Chiara, Ceconello; Subir, Das; Renzo, Vanna; Giulio, Cerullo; Dario, Polli
Opublikowane w: Journal of Visualized Experiments, Numer 185: e63709, 2022, Strona(/y) 1-25, ISSN 1940-087X
Wydawca: MYJoVE Corporation
DOI: 10.3791/63709

Multi-Class Cancer Subtyping in Salivary Gland Carcinomas with MALDI Imaging and Deep Learning

Autorzy: David Pertzborn; Christoph Arolt; Günther Ernst; Oliver J. Lechtenfeld; Jan Kaesler; Daniela Pelzel; Orlando Guntinas-Lichius; Ferdinand von Eggeling; Franziska Hoffmann
Opublikowane w: Cancers, Numer 14(17), 2022, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14174342

A Proposal to Perform High Contrast Imaging of Human Palatine Tonsil with Cross Polarized Optical Coherence Tomography

Autorzy: Gargi Sharma, Asha Parmar, Franziska Hoffmann, Katharina Geißler, Ferdinand von Eggeling, Orlando Guntinas-Lichius, Kanwarpal Singh
Opublikowane w: Photonics, Numer 9(4), 2022, ISSN 2304-6732
Wydawca: MDPI
DOI: 10.3390/photonics9040259

Artificial Intelligence in Classical and Quantum Photonics

Autorzy: Federico Vernuccio; Arianna Bresci; Valeria Cimini; Alessandro Giuseppi; Giulio Cerullo; Dario Polli; Carlo Michele Valensise
Opublikowane w: Laser & Photonics Reviews, Numer 16, 2022, Strona(/y) 2100399, ISSN 1863-8899
Wydawca: Wiley-VCH
DOI: 10.1002/lpor.202100399

Estimation of biological variance in coherent Raman microscopy data of two cell lines using chemometrics

Autorzy: Rajendhar Junjuri, Matteo Calvarese, MohammadSadegh Vafaeinezhad, Federico Vernuccio, Marco Ventura, Tobias Meyer-Zedler, Benedetta Gavazzoni, Dario Polli, Renzo Vanna, Italia Bongarzone, Silvia Ghislanzoni, Matteo Negro, Juergen Popp, Thomas Bocklitz
Opublikowane w: The Analyst, Numer 149, 2024, Strona(/y) 4395-4406, ISSN 0003-2654
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d4an00648h

CARS Imaging Advances Early Diagnosis of Cardiac Manifestation of Fabry Disease

Autorzy: Elen Tolstik, Nairveen Ali, Shuxia Guo, Paul Ebersbach, Dorothe Möllmann, Paula Arias-Loza, Johann Dierks, Irina Schuler, Erik Freier, Jörg Debus, Hideo A. Baba, Peter Nordbeck, Thomas Bocklitz and Kristina Lorenz
Opublikowane w: International Journal of Molecular Sciences, Numer 23(10), 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105345

Conference proceedings (9)

Multimodal multiphoton and vibrational microscopy reveals early therapy-induced senescence in human tumors: a non-invasive tool to prevent the risk of cancer relapse

Autorzy: Arianna Bresci, Francesco Manetti, Silvia Ghislanzoni, Federico Vernuccio, Salvatore Sorrentino, Chiara Ceconello, Renzo Vanna, Italia Bongarzone, Giulio Cerullo, Dario Polli
Opublikowane w: Proc. SPIE, Numer Vol. 12384, 2023
Wydawca: SPIE
DOI: 10.1117/12.2648415

Label free highly multimodal nonlinear endoscope using hollow core fiber

Autorzy: Hervé Rigneault, Septier, Gaelle Brévalle, Naveen Gajendra, J Saucourt, Géraud Bouwmans, Andy Cassez, Matteo Conforti, Alexandre Kudlinski
Opublikowane w:  J. Phys. Chem. B, Numer 127, 16, 2023
Wydawca: American Chemical Society

Plug-And-Play Stimulated Raman Microscopy System for Broadband Coherent Vibrational Imaging

Autorzy: Francesco Crisafi, Benedetta Talone, Andrea Ragni, Gabriele Di Noia
Opublikowane w: (CLEO/Europe-EQEC) 2023 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference, 2023
Wydawca: European Physical Society
DOI: 10.1109/cleo/europe-eqec57999.2023.10231815

Video-rate wide-field broadband coherent anti-Stokes Raman scattering microscopy

Autorzy: Chiara Ceconello, Federico Vernuccio, Arianna Bresci, Francesco Manetti, Salvatore Sorrentino, Renzo Vanna, Giulio Cerullo, Dario Polli
Opublikowane w: Proc. SPIE, Numer Vol. 12390, 2023
Wydawca: SPIE
DOI: 10.1117/12.2650628

Ultra-compact widely tunable dual-wavelength fiber-based sources for CARS and SRS imaging (Conference Presentation)

Autorzy: Armin Hoffmann; Florian Just; Christian Gaida; Sven Breitkopf; Oliver Herrfurth; Tobias Meyer-Zedler; Jürgen Popp; Tino Eidam; Jens Limpert
Opublikowane w: Proc. SPIE, Numer Vol. PC12391, 2023
Wydawca: SPIE
DOI: 10.1117/12.2649987

Quantitative molecular absorption of cosmetic active molecules in human skin using coherent Raman imaging (CARS and SRS)

Autorzy: Hervé Rigneault, Barbara Sarri
Opublikowane w: Conference Papers, Photonics West, 2023
Wydawca: Photonics West

Live stimulated Raman histology for the near-instant assessment of central nervous system samples

Autorzy: Barbara Sarri; Sandro Heuke; Chang Liu; Sebastien Boissonneau; Hervé Rigneault; Romain Appay
Opublikowane w: Proc. SPIE, Numer Vol. PC12373, 2023, ISSN 1520-6106
Wydawca: American Chemical Society
DOI: 10.1117/12.2648086

Multimodal vibrational and multiphoton nonlinear optical microscopy as a non-invasive tool to prevent human tumor recurrence

Autorzy: Arianna Bresci, Francesco Manetti, Silvia Ghislanzoni, Federico Vernuccio, Salvatore Sorrentino, Chiara Ceconello, Renzo Vanna, Italia Bongarzone, Giulio Cerullo, Dario Polli
Opublikowane w: Proc. SPIE, Numer Vol. 12627, 2023
Wydawca: SPIE
DOI: 10.1117/12.2670918

High-speed vibrational microscopy and deep-learning algorithms to image cells and tissues

Autorzy: Dario Polli, Federico Vernuccio, Alejandro De la Cadena, Arianna Bresci, Chiara Ceconello, Francesco Manetti, Salvatore Sorrentino, Subir Das, Renzo Vanna, Giulio Cerullo
Opublikowane w: Proc. SPIE LASE, Numer Vol. PC12406, 2023
Wydawca: SPIE
DOI: 10.1117/12.2648736

Non-peer reviewed articles (1)

High-resolution Raman imaging of >300 cells from human patients affected by nine different leukemia subtypes: a global clustering approach

Autorzy: Renzo Vanna; Andrea Masella; Manuela Bazzarelli; Paola Ronchi; Aufried T. M. Lenferink; Cristina Tresoldi; Carlo Morasso; Marzia Bedoni; Giulio Cerullo; Dario Polli; Fabio Ciceri; Giulia De Poli; Matteo Bregonzio; Cees Otto
Opublikowane w: ChemRxiv, 2024, ISSN 2573-2293
Wydawca: ChemRxiv
DOI: 10.26434/chemrxiv-2024-xpzhc-v2