PROTO - Advanced PeRsOnalized Therapies for Osteoarthritis – TACKLING INFLAMMATION TO IMPROVE PATIENT OUTCOMES

Informacje na temat projektu

PROTO

Identyfikator umowy o grant: 101095635

DOI

10.3030/101095635

Data podpisania przez KE 17 Listopada 2022

Data rozpoczęcia 1 Stycznia 2023

Data zakończenia 31 Grudnia 2027

Finansowanie w ramach

• Health

Koszt całkowity

€ 7 447 875,25

Wkład UE

€ 7 447 875,00

Koordynowany przez

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Websites, patent fillings, videos etc. (1)

Project website, project branding and visual identity

Definition of the project visual identity, design and development of project website

Documents, reports (3)

Establishment BtP Platform

Mobile/Responsive Patient Portal app development, supporting back end and legal/regulatory review (wth the aim to ensure patient connectivity during and after the trial and support informed decision making by relevant stakeholders).

Full appointment of the management and external advisory Boards

Details of the name of members of the board

Dissemination and Communication Plan

Initial plan, including communication activities

Data Management Plan (1)

DMP

Data Management Plan

Publikacje

Peer reviewed articles (12)

The Design of a Sample Rapid Magnetic Resonance Imaging (MRI) Acquisition Protocol Supporting Assessment of Multiple Articular Tissues and Pathologies in Knee Osteoarthritis

Autorzy: """Felix Eckstein, Thula Cannon Walter-Rittel, Akshay Chaudhari, Nicholas Brisson, Tazio Maleitzke, Georg N. Duda, Anna Wisser, Wolfgang Wirth, Tobias Winkler"""
Opublikowane w: Osteoarthritis & Cartilage Open, 2024, ISSN 2665-9131
Wydawca: Elsevier
DOI: 10.1016/j.ocarto.2024.100505

Nesting behavior is associated with body weight and grip strength loss in mice suffering from experimental arthritis

Autorzy: Tamara Dietrich, Annette Aigner, Alexander Hildebrandt, Jérôme Weber, Mara Meyer Günderoth, Katharina Hohlbaum, Johannes Keller, Serafeim Tsitsilonis & Tazio Maleitzke
Opublikowane w: Scientific Reports, 2023, ISSN 2045-2322
Wydawca: nature Publishing group
DOI: 10.1038/s41598-023-49720-y

Best Practice and Research in Clinical Rheumatology

Autorzy: Mobasheri A, Thudium CS, Bay-Jensen AC, Maleitzke T, Geissler S, Duda GN, Winkler T.
Opublikowane w: Best Pract Res Clin Rheumatol, 2023, ISSN 1521-6942
Wydawca: Wiley
DOI: 10.1016/j.berh.2023.101852

Advances in Extracellular Vesicle Research Over the Past Decade: Source and Isolation Method are Connected with Cargo and Function.

Autorzy: Poupardin R, Wolf M, Maeding N, Paniushkina L, Geissler S, Bergese P, Witwer KW, Schallmoser K, Fuhrmann G, Strunk D.
Opublikowane w: Advanced Healthcare materials, 2024, ISSN 2192-2659
Wydawca: wiley
DOI: 10.1002/adhm.202303941

The dual pro inflammatory and bone protective role of calcitonin gene related peptide alpha in age related osteoarthritis.

Autorzy: Alexander Hildebrandt, Tamara Dietrich, Jérôme Weber, Mara Meyer Günderoth, Sijia Zhou, Florian N. Fleckenstein, Shan Jiang, Tobias Winkler, Georg N. Duda, Serafeim Tsitsilonis, Johannes Keller and Tazio Maleitzke
Opublikowane w: Arthritis Research & Therapy, 2023, ISSN 1478-6354
Wydawca: Bio Med Center
DOI: 10.1186/s13075-023-03215-3

Chondrocyte Isolation from Loose Bodies-An Option for Reducing Donor Site Morbidity for Autologous Chondrocyte Implantation

Autorzy: Martin Textor, Arndt Hoburg, Rex Lehnigk, Carsten Perka, Georg Duda, Simon Reinke, Antje Blankenstein, Sarah Hochmann, Andreas Stockinger, Herbert Resch, Martin Wolf, Dirk Strunk, Sven Geissler
Opublikowane w: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Wydawca: MDPI
DOI: 10.3390/ijms24021484

Sexual dimorphism in peri-articular tissue anatomy - More keys to understanding sex-differences in osteoarthritis?

Autorzy: Felix Eckstein, Reinhard Putz, Wolfgang Wirth
Opublikowane w: Osteoarthritis & Cartilage Open, 2024, ISSN 2665-9131
Wydawca: Elsevier
DOI: 10.1016/j.ocarto.2024.100485

The clusterin connectome: Emerging players in chondrocyte biology and putative exploratory biomarkers of osteoarthritis

Autorzy: Kovács, Patrik; Pushparaj, Peter Natesan; Takács, Roland; Mobasheri, Ali; Matta, Csaba
Opublikowane w: Frontiers in immunology , 2023, ISSN 1664-3224
Wydawca: Frontiers media
DOI: 10.3389/FIMMU.2023.1103097

Minimal information for studies of extracellular vesicles (MISEV2023)

Autorzy: Joshua A. Welsh, Deborah C. I. Goberdhan, Lorraine O'Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, Dirk Strunk, Martin Wolf, et al
Opublikowane w: Journal of Extracellular Vesicles, 2024, ISSN 2001-3078
Wydawca: Wiley
DOI: 10.1002/jev2.12404

A sample rapid MRI acquisition protocol supporting assessment of multiple articular tissues and pathologies in early and advanced knee osteoarthritis

Autorzy: Wisser A, Walter-Rittel TC, Chaudhari A, Brisson NM, Maleitzke T, Duda GN, Wirth W, Winkler T, Eckstein F
Opublikowane w: Osteoarthritis Imaging, 2024, ISSN 2772-6541
Wydawca: Elsevier
DOI: 10.1016/j.ostima.2024.100221

Tissue engineering and future directions in regenerative medicine for knee cartilage repair: a comprehensive review

Autorzy: Primorac, Dragan; Molnar, Vilim; Tsoukas, Dimitrios; Uzieliene, Ilona; Tremolada, Carlo; Brlek, Petar; Klarić, Emil; Vidović, Dinko; Zekušić, Marija; Pachaleva, Jolita; Bernotiene, Eiva; Wilson, Adrian; Mobasheri, Ali 
Opublikowane w: Croatian medical journal , 2024, ISSN 0353-9504
Wydawca: Medicinska naklada
DOI: 10.3325/CMJ.2024.65.268

In Vitro Transcribed mRNA Immunogenicity Induces Chemokine-Mediated Lymphocyte Recruitment and Can Be Gradually Tailored by Uridine Modification

Autorzy: Drzeniek NM, Kahwaji N, Picht S, Dimitriou IM, Schlickeiser S, Moradian H, Geissler S, Schmueck-Henneresse M, Gossen M, Volk HD.
Opublikowane w: Advanced Science, 2024, ISSN 2198-3844
Wydawca: Wiley
DOI: 10.1002/advs.202308447