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Chromatin diseases: from basic mechanisms to therapy

Cel

The scope of this ITN is to promote research and training in the field of chromatin diseases. Chromatin diseases (CD) are genetic pathologies resulting from mutations in structural components of chromatin or in enzymes that biochemically modify chromatin, altering chromatin status and thereby causing drastic effects on gene expression. CD frequency ranges from very rare to quite common pathologies; so far for the vast majority of them no treatment is as yet available. Molecular studies on these pathologies thus have a twofold value: to shed light on the intricate interplays between different levels of control of gene expression acting in the mammalian nucleus and to pave the way toward new and more effective strategies to approach the treatment of this increasing class of diseases. Our students will take advantage of the integrated approach on multilayered gene regulation, the multidisciplinary nature and the cutting-edge methodologies, which are an integral part of this proposal. We thus expect to provide a framework for the very high-level training of young researchers, receiving a strong backgrounds in molecular, cellular and developmental biology, genomics, bioinformatics, chromatin biology and epigenetics. Furthermore, they will develop expertise in many cutting edge methodologies and tools, such as imaging, high throughput gene technologies, ChIP. As a result, the ESRs will be highly competitive in performing independent research in various areas of biology and will represent a new breed of scientists trained in contemporary post-genomic biology using advanced technological tools to tackle human disease.

Zaproszenie do składania wniosków

FP7-PEOPLE-ITN-2008
Zobacz inne projekty w ramach tego zaproszenia

Koordynator

CONSIGLIO NAZIONALE DELLE RICERCHE
Adres
Piazzale Aldo Moro 7
00185 Roma
Włochy

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Rodzaj działalności
Research Organisations
Kontakt administracyjny
Antonio Baldini (Prof.)
Wkład UE
€ 564 827

Uczestnicy (10)

UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II

Zakończenie uczestnictwa

Francja
Adres
Boulevard Charles Livon, Jardin Du Pharo 58
13284 Marseille
Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Celine Damon (Ms.)
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Grecja
Wkład UE
€ 371 880
Adres
Fleming Street 34
16672 Vari-athens

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Rodzaj działalności
Research Organisations
Kontakt administracyjny
George Kollias (Dr.)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
Wkład UE
€ 219 751
Adres
Trinity Lane The Old Schools
CB2 1TN Cambridge

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Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Edna Murphy (Ms.)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Wkład UE
€ 213 151
Adres
Wellington Square University Offices
OX1 2JD Oxford

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Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Lynne Hughson (Ms.)
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Hiszpania
Wkład UE
€ 380 355
Adres
Avenida Gran Via Hospitalet 199-203
08908 L'hospitalet De Llobregat

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Rodzaj działalności
Research Organisations
Kontakt administracyjny
Victoria Cochrane (Ms.)
UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
Włochy
Wkład UE
€ 212 351
Adres
Via Universita 4
41121 Modena

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Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Sebastiano Calandra Buonaura (Prof.)
UNIVERSITA DEGLI STUDI DELL'INSUBRIA
Włochy
Wkład UE
€ 205 751
Adres
Via Ravasi 2
21100 Varese

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Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Adriana Jacona (Mr.)
UNIVERSITE D'AIX MARSEILLE
Francja
Wkład UE
€ 206 452
Adres
Boulevard Charles Livon 58 Le Pharo
13284 Marseille

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Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Celine Damon (Ms.)
DIAGENODE
Belgia
Wkład UE
€ 200 309
Adres
Rue Du Bois Saint Jean 3 Liege Park Science
4102 Seraing

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Rodzaj działalności
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt administracyjny
Leon Etienne (Mr.)
UCL Elizabeth Garrett Anderson Institute for Women’s Health

Zakończenie uczestnictwa

United Kingdom
Adres
Gower Street
WC1E 6BT London
Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Greta Borg-Carbott (Ms.)