Cel A number of epidemiological studies have consistently demonstrated the protective effects of fruits and vegetables with respect to several age related diseases. The aim of this project is to investigate the protective action of agents with potential use as functional food constituents with respect to cancer, diabetes and cardiovascular disease. In collaboration between EU and Indian research centers the proposal features a multipronged approach, where the protective action of various non-toxic agents are studied in vitro as well as in rodent models with respect to induction of DNA lesions, tumours and biomarkers for the development of diabetes, diabetic retinopathy and atherosclerosis. In addition, reduced availability of carcinogens and inhibition of their metabolic activation are investigated. Testing of the protective efficacy of functional food components in intervention cross-over studies in humans exposed to carcinogens, that are normally present at significant levels in the environment, represents an approach that has rarely been resorted to, and will be implemented under this project in Europe as well as in India using sophisticated molecular, cytogenetic and other analytical methods. Although there has been remarkable progress in our understanding of the processes that lead to neoplasia and diabetes, the mechanisms underlying chemoprevention are, in general, little understood. The results from this project are expected to provide an improved insight with respect to this topic. Dziedzina nauki medical and health sciencesclinical medicinecardiologycardiovascular diseasesarteriosclerosismedical and health sciencesclinical medicineendocrinologydiabetesmedical and health sciencesclinical medicineoncologyagricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturevegetable growingmedical and health sciencesclinical medicineophthalmologyretinopathy Program(-y) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Temat(-y) KBBE-2009-2-7-01 - Development of functional foods and ingredients Zaproszenie do składania wniosków FP7-KBBE-2009-3 Zobacz inne projekty w ramach tego zaproszenia System finansowania CP-FP - Small or medium-scale focused research project Koordynator STOCKHOLMS UNIVERSITET Wkład UE € 599 400,00 Adres UNIVERSITETSVAGEN 10 10691 Stockholm Szwecja Zobacz na mapie Region Östra Sverige Stockholm Stockholms län Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Dag Jenssen (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (4) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko UNIVERSITA DEGLI STUDI DELLA TUSCIA Włochy Wkład UE € 229 692,00 Adres VIA S MARIA IN GRADI 4 01100 Viterbo Zobacz na mapie Region Centro (IT) Lazio Viterbo Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Daniela Cicalini (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych BIOCHEMICHES INSTITUT FUR UMWELTCARCINOGENE PROF. DR. GERNOT GRIMMER STIFTUNG Niemcy Wkład UE € 230 016,00 Adres LURUP 4 22927 GROSSHANSDORF Zobacz na mapie Rodzaj działalności Research Organisations Kontakt administracyjny Albrecht Seidel (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych INSTITUT ZA NUKLEARNE NAUKE VINCA INSTITUT OD NACIONALNOG ZNACAJA ZA REPUBLIKU SRBIJU, UNIVERZITET U BEGRADU Serbia Wkład UE € 183 600,00 Adres MIHAJLA PETROVICA ALASA 12 11307 Vinca Beograd Zobacz na mapie Region Србија - север Београдски регион Београдска област Rodzaj działalności Research Organisations Kontakt administracyjny Gordana Joksic (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych KAROLINSKA INSTITUTET Szwecja Wkład UE € 255 000,00 Adres Nobels Vag 5 17177 Stockholm Zobacz na mapie Region Östra Sverige Stockholm Stockholms län Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Kerstin Brismar (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych
