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ERA-NET for establishing synergies between the Joint Programming on Neurodegenerative Diseases Research and Horizon 2020

Rezultaty

Organization of a symposium for the dissemination of the results of JPco-fuND-funded research

Organization of a symposium for the dissemination of the results of JPcofuNDfunded research by ZonMw and ITMOH Month 30 60

Publikacje

Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells

Autorzy: Cicardi, Maria Elena; Cristofani, Riccardo; Rusmini, Paola; Meroni, Marco; Ferrari, Veronica; Vezzoli, Giulia; Tedesco, Barbara; Piccolella, Margherita; Messi, Elio; Galbiati, Mariarita; Boncoraglio, Alessandra; Carra, Serena; Crippa, Valeria; Poletti, Angelo
Opublikowane w: Scientific Reports, Numer 2, 2018, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-018-29658-2

Modeling Parkinson’s disease in midbrain-like organoids

Autorzy: Smits, L.M., Reinhardt, L., Reinhardt, P. et al.
Opublikowane w: npj Parkinsons Dis., 2019, ISSN 2373-8057
Wydawca: Springer Nature
DOI: 10.1038/s41531-019-0078-4

The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples

Autorzy: Duarte Lobo D, Nobre RJ, Oliveira Miranda C, Pereira D, Castelhano J, Sereno J, Koeppen A, Castelo-Branco M, Pereira de Almeida L.
Opublikowane w: Acta neuropathologica communications, 2020, ISSN 2051-5960
Wydawca: BioMed Central
DOI: 10.1186/s40478-020-00955-0

Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state

Autorzy: Chen G, Abelein A, Nilsson H, Leppert A, Andrade-Talavera Y, Tambaro S, Hemmingsson L, Roshan F, Landreh M, Biverstål H, Koeck P, Presto J, Hebert H, Fisahn A, Johansson J,
Opublikowane w: Nature communications, 2017, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-017-02056-4

Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease

Autorzy: Oliveira Miranda C, Marcelo A, Silva TP, Barata J, Vasconcelos-Ferreira A, Pereira D, Nóbrega C, Duarte S, Barros I, Alves J, Sereno J, Petrella LI, Castelhano J, Paiva VH, Rodrigues-Santos P, Alves V, Nunes-Correia I, Nobre RJ, Gomes C, Castelo-Branco M, Pereira de Almeida L.
Opublikowane w: Molecular Therapy, 2018, ISSN 1525-0016
Wydawca: Nature Publishing Group
DOI: 10.1016/j.ymthe.2018.07.007

The ability of liposomes, tailored for blood-brain barrier targeting, to reach the brain is dramatically affected by the disease state

Autorzy: Magro RD, Cox A, Zambelli V, Mancini S, Masserini M, Re F.
Opublikowane w: Nanomedicine (Lond), 2018, ISSN 1743-5889
Wydawca: Future Medicine Ltd.
DOI: 10.2217/nnm-2017-0317

A variant near DHCR24 associates with microstructural properties of white matter and peripheral lipid metabolism in adolescents

Autorzy: Sliz E., Shin J., Syme C., Patel Y., Parker N., Richer L., Gaudet D., Bennett S., Paus T., Pausova Z.
Opublikowane w: Molecular psychiatry, 2021, ISSN 1359-4184
Wydawca: Nature Publishing Group
DOI: 10.1038/s41380-019-0640-9

Neuronal DNA Methyltransferases: Epigenetic Mediators between Synaptic Activity and Gene Expression?

Autorzy: Gonca Bayraktar, Michael R. Kreutz
Opublikowane w: The Neuroscientist, 2017, ISSN 1073-8584
Wydawca: Sage Science Press
DOI: 10.1177/1073858417707457

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases

Autorzy: Paola Rusmini; Riccardo Cristofani; Mariarita Galbiati; Maria E. Cicardi; Marco Meroni; Veronica Ferrari; Giulia Vezzoli; Barbara Tedesco; Elio Messi; Margherita Piccolella; Serena Carra; Valeria Crippa; Valeria Crippa; Angelo Poletti; Angelo Poletti
Opublikowane w: Frontiers in Molecular Neuroscience, Vol 10 (2017), Numer 2, 2017, ISSN 1662-5099
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnmol.2017.00176

Survival Associations Using Perfusion and Diffusion Magnetic Resonance Imaging in Patients With Histologic and Genetic Defined Diffuse Glioma World Health Organization Grades II and III

Autorzy: Latysheva A, Emblem KE, Server A, Brandal P, Meling TR, Pahnke J, Hald JK.
Opublikowane w: Journal of computer assisted tomography, 2018, ISSN 0363-8715
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/rct.0000000000000742

High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain.

Autorzy: Axel Abelein; Gefei Chen; Kristīne Kitoka; Rihards Aleksis; Filips Oleskovs; Médoune Sarr; Michael Landreh; Jens Pahnke; Kerstin Nordling; Nina Kronqvist; Kristaps Jaudzems; Anna Rising; Anna Rising; Jan Johansson; Henrik Biverstål
Opublikowane w: Scientific Reports, Numer Vol 10, Iss 1,, 2020, Strona(/y) Pp 1-10, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-019-57143-x

Validation of behavioral phenotypes in the BACHD rat model

Autorzy: Novati A, Manfré G, Flunkert S, Van der Harst JE, Homberg JR, Wronski R, Nguyen HP.
Opublikowane w: Behavioural Brain Research, 2020, ISSN 0166-4328
Wydawca: Elsevier BV
DOI: 10.1016/j.bbr.2020.112783

In vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading

Autorzy: Kathrin Hemmer, Lisa M. Smits, Silvia Bolognin, Jens Schwamborn
Opublikowane w: Opera Medica et Physiologica, 2018, ISSN 2500-2295
Wydawca: Opera Medica et Physiologica
DOI: 10.1101/140178

Golgi-Cox impregnation combined with fluorescence staining of amyloid plaques reveals local spine loss in an Alzheimer mouse model

Autorzy: Kartalou GI, Endres T, Lessmann V, Gottmann K.
Opublikowane w: Journal of Neuroscience Methods, 2020, ISSN 0165-0270
Wydawca: Elsevier BV
DOI: 10.1016/j.jneumeth.2020.108797

Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease

Autorzy: Novati, Arianna; Hentrich, Thomas; Wassouf, Zinah; Weber, Jonasz J.; Yu-Taeger, Libo; Déglon, Nicole; Nguyen, Huu Phuc; Schulze-Hentrich, Julia M.
Opublikowane w: Scientific reports,, Numer vol. 8, no. 1, 2018, Strona(/y) 5803, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-018-24243-z

Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation.

Autorzy: Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takano T, Holtzman DM, Nedergaard M, Deane R.
Opublikowane w: Molecular Neurodegeneration, 2017, ISSN 1750-1326
Wydawca: BioMed Central
DOI: 10.1186/s13024-016-0147-7

Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin

Autorzy: Mediani, Laura; Guillén‐Boixet, Jordina; Vinet, Jonathan; Franzmann, Titus M; Bigi, Ilaria; Mateju, Daniel; Carrà, Arianna D; Morelli, Federica F; Tiago, Tatiana; Poser, Ina; Alberti, Simon; Carra, Serena
Opublikowane w: The EMBO Journal, Numer 1, 2019, ISSN 0261-4189
Wydawca: Nature Publishing Group
DOI: 10.15252/embj.2018101341

The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death

Autorzy: Riccardo Cristofani; Paola Rusmini; Mariarita Galbiati; Maria Elena Cicardi; Veronica Ferrari; Barbara Tedesco; Elena Casarotto; Marta Chierichetti; Elio Messi; Margherita Piccolella; Serena Carra; Valeria Crippa; Angelo Poletti; Angelo Poletti
Opublikowane w: Frontiers in Neuroscience, Vol 13 (2019), 2019, ISSN 1662-4548
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnins.2019.00796

Generation of a human induced pluripotent stem cell line (LL008 1.4) from a familial Alzheimer's disease patient carrying a double KM670/671NL (Swedish) mutation in APP gene.

Autorzy: Oksanen, Minna; Hyötyläinen, Ida; Voutilainen, Jenni; Puttonen, Katja A.; Hämäläinen, Riikka H.; Graff, Caroline; Lehtonen, Šárka; Koistinaho, Jari
Opublikowane w: Stem Cell Research, Vol 31, Iss , Pp 181-185 (2018), 2018, ISSN 1873-5061
Wydawca: Elsevier
DOI: 10.1016/j.scr.2018.07.024

Directing neuronal cell fate in vitro: Achievements and challenges

Autorzy: R.J.M.Riemensabc, D.L.A.van den Hovecd, M.Estelleraef, R.Delgado-Moralesac
Opublikowane w: Progress in Neurobiology, 2018, ISSN 0301-0082
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.pneurobio.2018.04.003

Global and regional development of the human cerebral cortex: Molecular acrchitecture and occupational aptitudes.

Autorzy: Shin, J., Ma, S., Hofer, E., Patel, Y., Vosberg, D. E., Tilley, S., Roshchupkin, G. V., Sousa, A. M. M., Jian, X., Gottesman, R., Mosley, T. H., Fornage, M., Saba, Y., Pirpamer, L., Schmidt, R., Schmidt, H., Carrion Castillo, A., Crivello, F., Mazoyer, B., Bis, J. C., Li, S., Yang, Q., Luciano, M., Karama, S., Lewis, L., Bastin, M. E., Harris, M. A., Wardlaw, J. M., Deary, I. E., Scholz, M., Loeff
Opublikowane w: Cerebral Cortex, 2020, ISSN 1047-3211
Wydawca: Oxford University Press
DOI: 10.1093/cercor/bhaa035

Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling

Autorzy: Garad M, Edelmann E, Lessmann V.
Opublikowane w: Scientific Reports, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-87769-9

Loss of zebrafish Ataxin-7, a SAGA subunit responsible for SCA7 retinopathy, causes ocular coloboma and malformation of photoreceptors

Autorzy: Samantha Carrillo-Rosas, Chantal Weber, Lorraine Fievet, Nadia Messaddeq, Alice Karam, Yvon Trottier;
Opublikowane w: Human molecular genetics, 2019, ISSN 0964-6906
Wydawca: Oxford University Press
DOI: 10.1093/hmg/ddy401

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

Autorzy: Wang, Jie; Choi, Jeong-Mo; Holehouse, Alex S.; Lee, Hyun O.; Zhang, Xiaojie; Jahnel, Marcus; Maharana, Shovamayee; Lemaitre, Régis; Pozniakovsky, Andrei; Drechsel, David; Poser, Ina; Pappu, Rohit V.; Alberti, Simon; Hyman, Anthony A.
Opublikowane w: Cells, 2018, ISSN 0092-8674
Wydawca: Cell Press
DOI: 10.1016/j.cell.2018.06.006

A kinetic model for Brain-Derived Neurotrophic Factor mediated spike timing-dependent LTP

Autorzy: Solinas SMG, Edelmann E, Leßmann V, Migliore M.
Opublikowane w: Plos Computational Biology, 2019, ISSN 1553-734X
Wydawca: Public Library of Science
DOI: 10.1371/journal.pcbi.1006975

Mitochondria in the signaling pathways that control longevity and health span.

Autorzy: Akbari M, Kirkwood TBL, Bohr VA.
Opublikowane w: Ageing Research Reviews, 2019, ISSN 1568-1637
Wydawca: Elsevier BV
DOI: 10.1016/j.arr.2019.100940

Can markers of biological age predict dependency in old age?

Autorzy: Jylhävä J, Jiang M, Foebel AD, Pedersen NL, Hägg S.
Opublikowane w: Biogerontology, 2019, ISSN 1389-5729
Wydawca: Kluwer Academic Publishers
DOI: 10.1007/s10522-019-09795-5

Impairment of macroautophagy in dopamine neurons has opposing effects on Parkinsonian pathology and behavior.

Autorzy: Hunn BHM, Vingill S, Threlfell S, Alegre-Abarrategui J, Magdelyns M, Deltheil T, Bengoa-Vergniory N, Oliver PL, Cioroch M, Doig NM, Bannerman DM, Cragg SJ and Wade-Martins R.
Opublikowane w: Cell reports, 2019, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2019.09.029

Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion

Autorzy: Niewiadomska-Cimicka A, Hache A, Trottier Y.
Opublikowane w: Frontiers in neuroscience, 2020, ISSN 1662-4548
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnins.2020.00571

ST Pipeline: an automated pipeline for spatial mapping of unique transcripts.

Autorzy: Navarro JF, Sjöstrand J, Salmén F, Lundeberg J, Ståhl PL.
Opublikowane w: Bioinformatics, 2017, ISSN 1367-4811
Wydawca: Oxford Academic
DOI: 10.1093/bioinformatics/btx211

Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

Autorzy: Steffen, J., Krohn, M., Schwitlick, C. et al.
Opublikowane w: acta neuropathol commun, Numer 5, 2017, Strona(/y) 49, ISSN 2051-5960
Wydawca: BioMed Central
DOI: 10.1186/s40478-017-0448-2

The Emerging Role of Mechanics in Synapse Formation and Plasticity

Autorzy: Kilinc D
Opublikowane w: Front. Cell. Neurosci, Numer 12, 2018, Strona(/y) 483, ISSN 1662-5102
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncel.2018.00483

Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs

Autorzy: Shrivastava AN, Bousset L, Renner M, Redeker V, Savistchenko J, Triller A, Melki R
Opublikowane w: Biophysical journal, 2020, ISSN 0006-3495
Wydawca: Biophysical Society
DOI: 10.1016/j.bpj.2020.01.022

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Autorzy: Ganesh Chauhan, Hieab H H Adams, Claudia L Satizabal, Joshua C Bis, Alexander Teumer, Muralidharan Sargurupremraj, Edith Hofer, Stella Trompet, Saima Hilal, Albert Vernon Smith, Xueqiu Jian, Rainer Malik, Matthew Traylor, Sara L Pulit, Philippe Amouyel, Bernard Mazoyer, Yi-Cheng Zhu, Sara Kaffashian, Sabrina Schilling, Gary W Beecham, Thomas J Montine, Gerard D Schellenberg, Olafur Kjartansson, Vi
Opublikowane w: Neurology, 2019, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000006851

Selection of Reference Genes for Normalization of Gene Expression Data in Blood of Machado-Joseph Disease/Spinocerebellar Ataxia Type 3 (MJD/SCA3) Subjects

Autorzy: Ferreira, A.F., Raposo, M., Vasconcelos, J. et al.
Opublikowane w: Journal of Molecular Neuroscience, Numer 69, 2019, Strona(/y) 450–455, ISSN 0895-8696
Wydawca: Humana Press, Inc.
DOI: 10.1007/s12031-019-01374-0

FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling

Autorzy: Jonathan Arias-Fuenzalida, JavierJarazo, Xiaobing Qing, Jonas Walter, Gemma Gomez-Giro, Sarah Louise Nickels, HolmZaehres45Hans Robert Schöler, Jens Christian Schwamborn
Opublikowane w: Stem Cell Reports, 2017, ISSN 2213-6711
Wydawca: Cell Press
DOI: 10.1016/j.stemcr.2017.08.026

Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo

Autorzy: Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, Menninger S, Zischinsky G, Eickhoff J, Fröb C, Bhattarai P, Arulmozhivarman G, Marrone L, Janosch A, Adachi K, Stehling M, Anderson EN, Abo-Rady M, Bickle M, Pandey UB, Reimer MM, Kizil C, Schöler HR, Nussbaumer P, Klebl B, and Sterneckert JL.
Opublikowane w: Stem Cell Reports, 2019, ISSN 2213-6711
Wydawca: Cell Press
DOI: 10.1016/j.stemcr.2019.01.015

The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice

Autorzy: Migdalska-Richards A, Wegrzynowicz M, Rusconi R, Deangeli G, Di Monte DA, Spillantini MG, Schapira AHV.
Opublikowane w: Brain, 2017, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awx221

Glycation in Huntington's Disease: A Possible Modifier and Target for Intervention

Autorzy: Brás IC, König A, Outeiro TF.
Opublikowane w: Journal of Huntington's Disease, 2019, ISSN 1879-6397
Wydawca: IOS Press
DOI: 10.3233/jhd-190366

Lactate-Induced Glucose Output Is Unchanged by Metformin at a Therapeutic Concentration - A Mass Spectrometry Imaging Study of the Perfused Rat Liver.

Autorzy: Giulio Calza; Elisabeth Nyberg; Elisabeth Nyberg; Matias Mäkinen; Rabah Soliymani; Annunziata Cascone; Dan Lindholm; Dan Lindholm; Emanuele Barborini; Marc Baumann; Maciej Lalowski; Ove Eriksson
Opublikowane w: Frontiers in Pharmacology, Vol 9 (2018), 2018, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2018.00141

Using a qPCR device to screen for modulators of ABC transporter activity: A step-by-step protocol

Autorzy: Luisa Möhle; Luisa Möhle; Barbora Schwarzová; Markus Krohn; Sven Marcel Stefan; Jens Pahnke
Opublikowane w: Journal of Pharmacological and Toxicological Methods, Numer 1, 2020, ISSN 1056-8719
Wydawca: Elsevier BV
DOI: 10.1016/j.vascn.2020.106882

A comparative study on pathological features of transgenic rat lines expressing either three or four repeat misfolded tau

Autorzy: Valachova B, Brezovakova V, Bugos O, Jadhav S, Smolek T, Novak P, Zilka N.
Opublikowane w: Journal of Comparative Neurology, 2018, ISSN 0021-9967
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/cne.24447

Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

Autorzy: Caldeira C, Cunha C, Vaz AR, Falcão AS, Barateiro A, Seixas E, Fernandes A, Brites D.
Opublikowane w: Frontiers in ageing neuroscience, 2017, ISSN 1663-4365
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnagi.2017.00277

Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring

Autorzy: Sizzano, F., Collino, S., Cominetti, O., Monti, D., Garagnani, P., Ostan, R., Pirazzini, C., Bacalini, M.G., Mari, D., Passarino, G.,…Franceschi C., et al.
Opublikowane w: Mediators of Inflammation, 2018, ISSN 0962-9351
Wydawca: Hindawi Publishing Corporation
DOI: 10.1155/2018/7109312

Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models

Autorzy: Mendonça LS, Nóbrega C, Tavino S, Brinkhaus M, Matos C, Tomé S, Moreira R, Henriques D, Kaspar BK, Pereira de Almeida L.
Opublikowane w: Human Molecular Genetics, 2019, ISSN 0964-6906
Wydawca: Oxford University Press
DOI: 10.1093/hmg/ddz097

Revisiting rodent models: Octodon degus as Alzheimer's disease model?

Autorzy: Steffen J, Krohn M, Paarmann K, Schwitlick C, Bruning T, Marreiros R, Muller- Schiffmann A, Korth C, Braun K, Pahnke J
Opublikowane w: Acta neuropathologica communications, 2016, ISSN 2051-5960
Wydawca: BioMed Central
DOI: 10.1186/s40478-016-0363-y

Inhibition of copper transporter 1 prevents α-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson's disease

Autorzy: Gou DH, Huang TT, Li W, Gao XD, Haikal C, Wang XH, Song DY, Liang X, Zhu L, Tang Y, Ding C, Li JY.
Opublikowane w: Redox Biology, 2021, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/j.redox.2020.101795

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease

Autorzy: Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, Sogne E, Falqui A, Petricca L, Verani M, Martufi P, Caricasole A, Bresciani A, Cecchetti O, Rivetti di Val Cervo P, Sancini G, Riess O, Nguyen H, Seipold L, Saftig P, Biella G, Cattaneo E, Zuccato C.
Opublikowane w: Journal of Clinical Investigation, 2019, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci120616

CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons

Autorzy: Xiaobing Qing 1, Jonas Walter 1, Javier Jarazo 1, Jonathan Arias-Fuenzalida 1, Anna-Lena Hillje 1, Jens C Schwamborn 2
Opublikowane w: Stem Cell Res, 2018, ISSN 1873-5061
Wydawca: Elsevier
DOI: 10.1016/j.scr.2017.08.013

The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates

Autorzy: Claudio Franceschi 1, Paolo Garagnani 2 3 4 5, Cristina Morsiani 2, Maria Conte 2, Aurelia Santoro 2 6, Andrea Grignolio 7, Daniela Monti 8, Miriam Capri 2 6, Stefano Salvioli
Opublikowane w: Front Med (Lausanne), 2018, ISSN 2296-858X
Wydawca: Frontiers Media SA
DOI: 10.3389/fmed.2018.00061

Alpha-synuclein and the prion hypothesis in Parkinson's disease

Autorzy: Melki R.
Opublikowane w: Revue neurologique (Paris), 2018, ISSN 0035-3787
Wydawca: Elsevier Masson
DOI: 10.1016/j.neurol.2018.08.002

Neural Correlates of the Dual-Pathway Model for ADHD in Adolescents

Autorzy: Chun Shen, M.Sc., Qiang Luo, Ph.D., Tianye Jia, Ph.D., Qi Zhao, M.Sc., Sylvane Desrivières, Ph.D., Erin Burke Quinlan, Ph.D., Tobias Banaschewski, M.D., Ph.D., Sabina Millenet, D.Psych., Arun L.W. Bokde, Ph.D., Christian Büchel, M.D., Herta Flor, Ph.D., Vincent Frouin, Ph.D., Hugh Garavan, Ph.D., Penny Gowland, Ph.D., Andreas Heinz, M.D., Ph.D., Bernd Ittermann, Ph.D., Jean-Luc Martinot, M.D., P
Opublikowane w: American journal of psychiatry, 2020, ISSN 0002-953X
Wydawca: American Psychiatric Publishing, Inc.
DOI: 10.1176/appi.ajp.2020.19020183

3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing

Autorzy: Silvia Bolognin 1 2, Marie Fossépré 1 2, Xiaobing Qing 1, Javier Jarazo 1, Janez Ščančar 3, Edinson Lucumi Moreno 1, Sarah L Nickels 1, Kobi Wasner 1, Nassima Ouzren 1, Jonas Walter 1 2, Anne Grünewald 1 4, Enrico Glaab 1, Luis Salamanca 1, Ronan M T Fleming 1, Paul M A Antony 1, Jens C Schwamborn
Opublikowane w: Adv Sci, 2019, ISSN 2198-3844
Wydawca: Wiley-VCH GmbH, Weinheim
DOI: 10.1002/advs.201800927

Secretome from SH-SY5Y APP Swe cells trigger time-dependent CHME3 microglia activation phenotypes, ultimately leading to miR-21 exosome shuttling

Autorzy: Fernandes A, Ribeiro AR, Monteiro M, Garcia G, Vaz AR, Brites D
Opublikowane w: Biochimie, 2018, ISSN 0300-9084
Wydawca: Elsevier BV
DOI: 10.1016/j.biochi.2018.05.015

Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease

Autorzy: Grozdanov V, Bousset L, Hoffmeister M, Bliederhaeuser C, Meier C, Madiona K, Pieri L, Kiechle M, McLean PJ, Kassubek J, Behrends C, Ludolph AC, Weishaupt JH, Melki R, Danzer KM
Opublikowane w: Annals of neurology, 2019, ISSN 0364-5134
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/ana.25557

FTY720 treatment starting after onset of symptoms reverses synaptic and memory deficits in an AD mouse model.

Autorzy: Kartalou G-I, Salgueiro Pereira SP, Endres T, Lesnikova A, Casarotto P, Pousinha P, Delanoe K, Edelmann E, Castrén E, Gottmann K, Marie H, Lessmann V.
Opublikowane w: BioRxiv, 2019, ISSN 2692-8205
Wydawca: BioRxiv
DOI: 10.1101/2019.12.15.868026

Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies

Autorzy: Pomeshchik Y, Klementieva O, Gil J, Martinsson I, Hansen MG, de Vries T, Sancho-Balsells A, Russ K, Savchenko E, Collin A, Vaz AR, Bagnoli S, Nacmias B, Rampon C, Sorbi S, Brites D, Marko-Varga G, Kokaia Z, Rezeli M, Gouras GK, Roybon L.
Opublikowane w: Stem Cell Reports, 2020, ISSN 2213-6711
Wydawca: Cell Press
DOI: 10.1016/j.stemcr.2020.06.001

Quality Control of Membraneless Organelles.

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