Unleash IMM’s research excellence in immunity and infection through twinning to infect Lisbon and Portugal with its increase in competitiveness and innovation

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

EC KPI Widening indicator application for the 3-year window time prior to TwinnToInfect
Second TwinnToInfect Joint Summer School
KPIs definition for TwinnToInfect
First TwinnToInfect Joint Summer School

Publikacje

The Use of Machine Learning Methodologies to Analyse Antibiotic and Biocide Susceptibility in Staphylococcus aureus

Autorzy: Joana Rosado Coelho, João André Carriço, Daniel Knight, Jose-Luis Martínez, Ian Morrissey, Marco Rinaldo Oggioni, Ana Teresa Freitas
Opublikowane w: PLoS ONE, Numer 8/2, 2013, Strona(/y) e55582, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0055582

Enteric Mucosa Integrity in the Presence of a Preserved Innate Interleukin 22 Compartment in HIV Type 1-Treated Individuals

Autorzy: S. M. Fernandes, A. R. Pires, C. Ferreira, R. B. Foxall, J. Rino, C. Santos, L. Correia, J. Pocas, H. Veiga-Fernandes, A. E. Sousa
Opublikowane w: Journal of Infectious Diseases, Numer 210/4, 2014, Strona(/y) 630-640, ISSN 0022-1899
Wydawca: University of Chicago Press
DOI: 10.1093/infdis/jiu126

The Genetic Basis of Escherichia coli Pathoadaptation to Macrophages

Autorzy: Migla Miskinyte, Ana Sousa, Ricardo S. Ramiro, Jorge A. Moura de Sousa, Jerzy Kotlinowski, Iris Caramalho, Sara Magalhães, Miguel P. Soares, Isabel Gordo
Opublikowane w: PLoS Pathogens, Numer 9/12, 2013, Strona(/y) e1003802, ISSN 1553-7366
Wydawca: Public Library of Science
DOI: 10.1371/journal.ppat.1003802

Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites

Autorzy: Nuno A. L. Pereira, Ângelo Monteiro, Marta Machado, Jiri Gut, Elies Molins, M. Jesus Perry, Jorge Dourado, Rui Moreira, Philip J. Rosenthal, Miguel Prudêncio, Maria M. M. Santos
Opublikowane w: ChemMedChem, Numer 10/12, 2015, Strona(/y) 2080-2089, ISSN 1860-7179
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.201500429

Automatic determination of NET (neutrophil extracellular traps) coverage in fluorescent microscopy images

Autorzy: Luis Pedro Coelho, Catarina Pato, Ana Friães, Ariane Neumann, Maren von Köckritz-Blickwede, Mário Ramirez, João André Carriço
Opublikowane w: Bioinformatics, Numer 31/14, 2015, Strona(/y) 2364-2370, ISSN 1367-4803
Wydawca: Oxford University Press
DOI: 10.1093/bioinformatics/btv156

Not Seeing the Forest for the Trees: Size of the Minimum Spanning Trees (MSTs) Forest and Branch Significance in MST-Based Phylogenetic Analysis

Autorzy: Andreia Sofia Teixeira, Pedro T. Monteiro, João A Carriço, Mário Ramirez, Alexandre P. Francisco
Opublikowane w: PLOS ONE, Numer 10/3, 2015, Strona(/y) e0119315, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0119315

Scarlet Fever Is Caused By a Limited Number of Streptococcus pyogenes Lineages and Is Associated with the Exotoxin Genes ssa, speA and speC

Autorzy: Catarina Silva-Costa, Joao A. Carriço, Mario Ramirez, Jose Melo-Cristino
Opublikowane w: The Pediatric Infectious Disease Journal, Numer 33/3, 2014, Strona(/y) 306-310, ISSN 0891-3668
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/INF.0000000000000088

The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function

Autorzy: Diogo Fonseca-Pereira, Sílvia Arroz-Madeira, Mariana Rodrigues-Campos, Inês A. M. Barbosa, Rita G. Domingues, Teresa Bento, Afonso R. M. Almeida, Hélder Ribeiro, Alexandre J. Potocnik, Hideki Enomoto, Henrique Veiga-Fernandes
Opublikowane w: Nature, Numer 514/7520, 2014, Strona(/y) 98-101, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/nature13498

Adjuvant facilitates tolerance induction to factor VIII in hemophilic mice through a Foxp3-independent mechanism that relies on IL-10

Autorzy: V. G. Oliveira, A. Agua-Doce, M. A. Curotto de Lafaille, J. J. Lafaille, L. Graca
Opublikowane w: Blood, Numer 121/19, 2013, Strona(/y) 3936-3945, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2012-09-457135

Tuberculosis with malaria or HIV co-infection in a large hospital in Luanda, Angola

Autorzy: Emília Valadas, Augusto Gomes,Ana Sutre, Sara Brilha, Afonso Wete, Thomas Hänscheid, Francisco Antunes
Opublikowane w: Journal of Infection in Developing Countries, Numer 6, 2013, ISSN 1972-2680
Wydawca: Open Learning on Enteric Pathogens

Novel Endoperoxide-Based Transmission-Blocking Antimalarials with Liver- and Blood-Schizontocidal Activities

Autorzy: Daniela Miranda, Rita Capela, Inês S. Albuquerque, Patrícia Meireles, Isa Paiva, Fátima Nogueira, Richard Amewu, Jiri Gut, Philip J. Rosenthal, Rudi Oliveira, Maria M. Mota, Rui Moreira, Francesc Marti, Miguel Prudêncio, Paul M. O’Neill, Francisca Lopes
Opublikowane w: ACS Medicinal Chemistry Letters, Numer 5/2, 2014, Strona(/y) 108-112, ISSN 1948-5875
Wydawca: American Chemical Society
DOI: 10.1021/ml4002985

Assessment of Dual Life Stage Antiplasmodial Activity of British Seaweeds

Autorzy: Jasmine Spavieri, Andrea Allmendinger, Marcel Kaiser, Maurice Itoe, Gerald Blunden, Maria Mota, Deniz Tasdemir
Opublikowane w: Marine Drugs, Numer 11/10, 2013, Strona(/y) 4019-4034, ISSN 1660-3397
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md11104019

Using argument notation to engineer biological simulations with increased confidence

Autorzy: Kieran Alden, Paul S. Andrews, Fiona A. C. Polack, Henrique Veiga-Fernandes, Mark C. Coles, Jon Timmis
Opublikowane w: Journal of the Royal Society Interface, Numer 12, 2015, ISSN 1742-5689
Wydawca: The Royal Society
DOI: 10.1098/rsif.2014.1059

Defining Immune Engagement Thresholds for In Vivo Control of Virus-Driven Lymphoproliferation

Autorzy: Cristina Godinho-Silva, Sofia Marques, Diana Fontinha, Henrique Veiga-Fernandes, Philip G. Stevenson, J. Pedro Simas
Opublikowane w: PLoS Pathogens, Numer 10/6, 2014, Strona(/y) e1004220, ISSN 1553-7366
Wydawca: Public Library of Science
DOI: 10.1371/journal.ppat.1004220

Innate Immunity Induced by Plasmodium Liver Infection Inhibits Malaria Reinfections

Autorzy: Peter Liehl, Patrícia Meireles, Inês S. Albuquerque, Mykola Pinkevych, Fernanda Baptista, Maria M. Mota, Miles P. Davenport, Miguel Prudêncio
Opublikowane w: Infection and Immunity, Numer 83/3, 2015, Strona(/y) 1172-1180, ISSN 0019-9567
Wydawca: American Society for Microbiology
DOI: 10.1128/IAI.02796-14

Establishment of Murine Gammaherpesvirus Latency in B Cells Is Not a Stochastic Event

Autorzy: Jérémie Decalf, Cristina Godinho-Silva, Diana Fontinha, Sofia Marques, J. Pedro Simas
Opublikowane w: PLoS Pathogens, Numer 10/7, 2014, Strona(/y) e1004269, ISSN 1553-7366
Wydawca: Public Library of Science
DOI: 10.1371/journal.ppat.1004269

Gut disruption in HIV-2 infection despite reduced viremia

Autorzy: Susana M. Fernandes, Ana R. Pires, Cristina Ferreira, Rita Tendeiro, Luís Correia, Sérgio E. Paulo, Rui M.M. Victorino, Ana E. Sousa
Opublikowane w: AIDS, Numer 28/2, 2014, Strona(/y) 290-292, ISSN 0269-9370
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/QAD.0000000000000114

Thymic HIV-2 Infection Uncovers Posttranscriptional Control of Viral Replication in Human Thymocytes

Autorzy: Helena Nunes-Cabaço, Paula Matoso, Russell B. Foxall, Rita Tendeiro, Ana R. Pires, Tânia Carvalho, Ana I. Pinheiro, Rui S. Soares, Ana E. Sousa
Opublikowane w: Journal of Virology, Numer 89/4, 2015, Strona(/y) 2201-2208, ISSN 0022-538X
Wydawca: American Society for Microbiology
DOI: 10.1128/JVI.03047-14

Insight into lymphoid tissue morphogenesis

Autorzy: Mark Coles, Henrique Veiga-Fernandes
Opublikowane w: Immunology Letters, Numer 156/1-2, 2013, Strona(/y) 46-53, ISSN 0165-2478
Wydawca: Elsevier BV
DOI: 10.1016/j.imlet.2013.08.001

Dual-stage triterpenoids from an African medicinal plant targeting the malaria parasite

Autorzy: Cátia Ramalhete, Filipa P. da Cruz, Silva Mulhovo, Inês J. Sousa, Miguel X. Fernandes, Miguel Prudêncio, Maria-José U. Ferreira
Opublikowane w: Bioorganic & Medicinal Chemistry, Numer 22/15, 2014, Strona(/y) 3887-3890, ISSN 0968-0896
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.bmc.2014.06.019

At the Bench: Preclinical rationale for exploiting NK cells and T lymphocytes for the treatment of high-risk leukemias

Autorzy: H. Norell, A. Moretta, B. Silva-Santos, L. Moretta
Opublikowane w: Journal of Leukocyte Biology, Numer 94/6, 2013, Strona(/y) 1123-1139, ISSN 0741-5400
Wydawca: Federation of American Societies for Experimental Biology
DOI: 10.1189/jlb.0613312

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

Autorzy: Peter Liehl, Vanessa Zuzarte-Luís, Jennie Chan, Thomas Zillinger, Fernanda Baptista, Daniel Carapau, Madlen Konert, Kirsten K Hanson, Céline Carret, Caroline Lassnig, Mathias Müller, Ulrich Kalinke, Mohsan Saeed, Angelo Ferreira Chora, Douglas T Golenbock, Birgit Strobl, Miguel Prudêncio, Luis P Coelho, Stefan H Kappe, Giulio Superti-Furga, Andreas Pichlmair, Ana M Vigário, Charles M Rice, Katherine A Fitzgerald, Winfried Barchet, Maria M Mota
Opublikowane w: Nature Medicine, Numer 20/1, 2013, Strona(/y) 47-53, ISSN 1078-8956
Wydawca: Nature Publishing Group
DOI: 10.1038/nm.3424

Human regulatory T-cell development is dictated by Interleukin-2 and -15 expressed in a non-overlapping pattern in the thymus

Autorzy: Iris Caramalho, Vânia Nunes-Silva, Ana R. Pires, Catarina Mota, Ana I. Pinto, Helena Nunes-Cabaço, Russell B. Foxall, Ana E. Sousa
Opublikowane w: Journal of Autoimmunity, Numer 56, 2015, Strona(/y) 98-110, ISSN 0896-8411
Wydawca: Academic Press
DOI: 10.1016/j.jaut.2014.11.002

Mechanisms Underlying CD4+ Treg Immune Regulation in the Adult: From Experiments to Models

Autorzy: Marta Caridade, Luis Graca, Ruy M. Ribeiro
Opublikowane w: Frontiers in Immunology, Numer 4, 2013, ISSN 1664-3224
Wydawca: Frontiers Editorial Office
DOI: 10.3389/fimmu.2013.00378

The fate of CD4+ T cells under tolerance-inducing stimulation: a modeling perspective

Autorzy: Marta Caridade, Vanessa G Oliveira, Ana Agua-Doce, Luis Graca, Ruy M Ribeiro
Opublikowane w: Immunology and Cell Biology, Numer 91/10, 2013, Strona(/y) 652-660, ISSN 0818-9641
Wydawca: Blackwell Publishing Inc.
DOI: 10.1038/icb.2013.63

In Vitro Alterations Do Not Reflect a Requirement for Host Cell Cycle Progression during Plasmodium Liver Stage Infection

Autorzy: Kirsten K. Hanson, Sandra March, Shengyong Ng, Sangeeta N. Bhatia, Maria M. Mota
Opublikowane w: Eukaryotic Cell, Numer 14/1, 2014, Strona(/y) 96-103, ISSN 1535-9778
Wydawca: American Society for Microbiology
DOI: 10.1128/EC.00166-14

Impact of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus

Autorzy: Sofia Santos Costa, Miguel Viveiros, Adriana E. Rosato, José Melo-Cristino, Isabel Couto
Opublikowane w: BMC Microbiology, 2015, ISSN 1471-2180
Wydawca: BioMed Central
DOI: 10.1186/s12866-015-0572-8

Repairing thymic function

Autorzy: Helena Nunes-Cabaço, Ana E. Sousa
Opublikowane w: Current Opinion in Organ Transplantation, 2013, Strona(/y) 1, ISSN 1087-2418
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/MOT.0b013e3283615df9

Chemical Interrogation of the Malaria Kinome

Autorzy: Emily R. Derbyshire, Vanessa Zuzarte-Luís, Andreia D. Magalhães, Nobutaka Kato, Paul C. Sanschagrin, Jinhua Wang, Wenjun Zhou, Chandrasekhar V. Miduturu, Ralph Mazitschek, Piotr Sliz, Maria M. Mota, Nathanael S. Gray, Jon Clardy
Opublikowane w: ChemBioChem, Numer 15/13, 2014, Strona(/y) 1920-1930, ISSN 1439-4227
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201400025

Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells

Autorzy: Diana Fontinha, Filipa B. Lopes, Sofia Marques, J. Pedro Simas
Opublikowane w: PLOS ONE, Numer 10/11, 2015, Strona(/y) e0142540, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0142540

T rypanosoma brucei histone H1 inhibits RNA polymerase I transcription and is important for parasite fitness in vivo

Autorzy: Ana C. Pena, Mafalda R. Pimentel, Helena Manso, Rita Vaz-Drago, Daniel Pinto-Neves, Francisco Aresta-Branco, Filipa Rijo-Ferreira, Fabien Guegan, Luis Pedro Coelho, Maria Carmo-Fonseca, Nuno L. Barbosa-Morais, Luisa M. Figueiredo
Opublikowane w: Molecular Microbiology, Numer 93/4, 2014, Strona(/y) 645-663, ISSN 0950-382X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/mmi.12677

The hemozoin conundrum: is malaria pigment immune-activating, inhibiting, or simply a bystander?

Autorzy: Márcia Boura, Rosangela Frita, Ana Góis, Tânia Carvalho, Thomas Hänscheid
Opublikowane w: Trends in Parasitology, Numer 29/10, 2013, Strona(/y) 469-476, ISSN 1471-4922
Wydawca: Elsevier BV
DOI: 10.1016/j.pt.2013.07.005

First case of infection with vancomycin-resistant Staphylococcus aureus in Europe

Autorzy: José Melo-Cristino, Cristina Resina, Viviana Manuel, Luís Lito, Mário Ramirez
Opublikowane w: The Lancet, Numer 382/9888, 2013, Strona(/y) 205, ISSN 0140-6736
Wydawca: The Lancet Publishing Group
DOI: 10.1016/S0140-6736(13)61219-2

Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis

Autorzy: Nuno Figueiredo, Angelo Chora, Helena Raquel, Nadja Pejanovic, Pedro Pereira, Björn Hartleben, Ana Neves-Costa, Catarina Moita, Dora Pedroso, Andreia Pinto, Sofia Marques, Hafeez Faridi, Paulo Costa, Raffaella Gozzelino, Jimmy L. Zhao, Miguel P. Soares, Margarida Gama-Carvalho, Jennifer Martinez, Qingshuo Zhang, Gerd Döring, Markus Grompe, J. Pedro Simas, Tobias B. Huber, David Baltimore, Vineet Gupta, Douglas R. Green, João A. Ferreira, Luis F. Moita
Opublikowane w: Immunity, Numer 39/5, 2013, Strona(/y) 874-884, ISSN 1074-7613
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2013.08.039

Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro

Autorzy: S. Ng, S. March, A. Galstian, K. Hanson, T. Carvalho, M. M. Mota, S. N. Bhatia
Opublikowane w: Disease Models & Mechanisms, Numer 7/2, 2014, Strona(/y) 215-224, ISSN 1754-8403
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/dmm.013490

Identification of H-type BSE in Portugal

Autorzy: Leonor Orge, Carla Guedes Machado, Luísa Ramalho, Renata Carvalho, João Silva, Paula Almeida, Paula Tavares, Cristina Ochoa, Carla Lima, Maria J Marques Pinto, J Pedro Simas
Opublikowane w: Prion, Numer 9/1, 2015, Strona(/y) 22-28, ISSN 1933-6896
Wydawca: Landes Bioscience
DOI: 10.1080/19336896.2014.997615

Malaria infections: What and how can mice teach us

Autorzy: Vanessa Zuzarte-Luis, Maria M. Mota, Ana M. Vigário
Opublikowane w: Journal of Immunological Methods, Numer 410, 2014, Strona(/y) 113-122, ISSN 0022-1759
Wydawca: Elsevier BV
DOI: 10.1016/j.jim.2014.05.001

KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA

Autorzy: Rajesh Ponnusamy, Maxim V. Petoukhov, Bruno Correia, Tania F. Custodio, Franceline Juillard, Min Tan, Marta Pires de Miranda, Maria A. Carrondo, J. Pedro Simas, Kenneth M. Kaye, Dmitri I. Svergun, Colin E. McVey
Opublikowane w: Nucleic Acids Research, 2015, Strona(/y) gkv987, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkv987

Bacillus invictae sp. nov., isolated from a health product

Autorzy: R. Branquinho, C. Sousa, H. Osorio, L. Meirinhos-Soares, J. Lopes, J. A. Carrico, H.-J. Busse, A. Abdulmawjood, G. Klein, P. Kampfer, M. E. Pintado, L. V. Peixe
Opublikowane w: INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Numer 64/Pt 11, 2014, Strona(/y) 3867-3876, ISSN 1466-5026
Wydawca: Society for General Microbiology
DOI: 10.1099/ijs.0.067850-0

Non-Invasive Pneumococcal Pneumonia in Portugal—Serotype Distribution and Antimicrobial Resistance

Autorzy: Andreia N. Horácio, Joana P. Lopes, Mário Ramirez, José Melo-Cristino
Opublikowane w: PLoS ONE, Numer 9/7, 2014, Strona(/y) e103092, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0103092

Genomic Analysis Reveals the Molecular Basis for Capsule Loss in the Group B Streptococcus Population

Autorzy: Roberto Rosini, Edmondo Campisi, Matteo De Chiara, Hervé Tettelin, Daniela Rinaudo, Chiara Toniolo, Matteo Metruccio, Silvia Guidotti, Uffe B. Skov Sørensen, Mogens Kilian, Mario Ramirez, Robert Janulczyk, Claudio Donati, Guido Grandi, Immaculada Margarit
Opublikowane w: PLOS ONE, Numer 10/5, 2015, Strona(/y) e0125985, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0125985

Bioinformatics in bacterial molecular epidemiology and public health: databases, tools and the next-generation sequencing revolution

Autorzy: J. A. Carriço, A. J. Sabat, A.W. Friedrich, Mário Ramirez
Opublikowane w: Eurosurveillance, Numer 52, 2013, ISSN 1560-7917
Wydawca: EUR CENTRE DIS PREVENTION & CONTROL

Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins

Autorzy: K. K. Hanson, A. S. Ressurreicao, K. Buchholz, M. Prudencio, J. D. Herman-Ornelas, M. Rebelo, W. L. Beatty, D. F. Wirth, T. Hanscheid, R. Moreira, M. Marti, M. M. Mota
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 110/30, 2013, Strona(/y) E2838-E2847, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1306097110

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

Autorzy: Serge A. van de Pavert, Manuela Ferreira, Rita G. Domingues, Hélder Ribeiro, Rosalie Molenaar, Lara Moreira-Santos, Francisca F. Almeida, Sales Ibiza, Inês Barbosa, Gera Goverse, Carlos Labão-Almeida, Cristina Godinho-Silva, Tanja Konijn, Dennis Schooneman, Tom O’Toole, Mark R. Mizee, Yasmin Habani, Esther Haak, Fabio R. Santori, Dan R. Littman, Stefan Schulte-Merker, Elaine Dzierzak, J. Pedro Simas, Reina E. Mebius, Henrique Veiga-Fernandes
Opublikowane w: Nature, Numer 508/7494, 2014, Strona(/y) 123-127, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/nature13158

Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels

Autorzy: A. M. Gomes, M. V. D. Soares, P. Ribeiro, J. Caldas, V. Povoa, L. R. Martins, A. Melao, A. Serra-Caetano, A. B. de Sousa, J. F. Lacerda, J. T. Barata
Opublikowane w: Haematologica, Numer 99/6, 2014, Strona(/y) 1062-1068, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2013.096438

NFIL3 Orchestrates the Emergence of Common Helper Innate Lymphoid Cell Precursors

Autorzy: Wei Xu, Rita G. Domingues, Diogo Fonseca-Pereira, Manuela Ferreira, Hélder Ribeiro, Silvia Lopez-Lastra, Yasutaka Motomura, Lara Moreira-Santos, Franck Bihl, Véronique Braud, Barbara Kee, Hugh Brady, Mark C. Coles, Christian Vosshenrich, Masato Kubo, James P. Di Santo, Henrique Veiga-Fernandes
Opublikowane w: Cell Reports, Numer 10/12, 2015, Strona(/y) 2043-2054, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2015.02.057

Classification of current anticancer immunotherapies

Autorzy: Lorenzo Galluzzi, Erika Vacchelli, José-Manuel Bravo-San Pedro, Aitziber Buqué, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka Fučíková, Dmitry I. Gabrilovich, Jérôme Galon, Abhishek Garg, François Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk Jäger, Pawel Kalinski, Klas Kärre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine Sautès-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, Benoît J. Van Den Eynde, Richard Vile, Hermann Wagner, Jeffrey S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, Guido Kroemer
Opublikowane w: Oncotarget, Numer 5/24, 2015, Strona(/y) 12472-12508, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.2998

BAFF and TACI Gene Expression Are Increased in Patients with Untreated Very Early Rheumatoid Arthritis

Autorzy: R. A. Moura, H. Canhao, J. Polido-Pereira, A. M. Rodrigues, M. Navalho, A. F. Mourao, C. Resende, R. Campanilho-Marques, J. Madruga Dias, J. A. P. da Silva, L. Graca, J. E. Fonseca
Opublikowane w: The Journal of Rheumatology, Numer 40/8, 2013, Strona(/y) 1293-1302, ISSN 0315-162X
Wydawca: Journal of Rheumatology Publishing Co., Ltd.
DOI: 10.3899/jrheum.121110

Assessing anti-malarial drug effects ex vivo using the haemozoin detection assay

Autorzy: Maria Rebelo, Carolina Tempera, José F Fernandes, Martin P Grobusch, Thomas Hänscheid
Opublikowane w: Malaria Journal, Numer 14/1, 2015, ISSN 1475-2875
Wydawca: BioMed Central
DOI: 10.1186/s12936-015-0657-8

A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

Autorzy: Sandra March, Shengyong Ng, Soundarapandian Velmurugan, Ani Galstian, Jing Shan, David J. Logan, Anne E. Carpenter, David Thomas, B. Kim Lee Sim, Maria M. Mota, Stephen L. Hoffman, Sangeeta N. Bhatia
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Wydawca: Frontiers Editorial Office
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Flavones as isosteres of 4(1H)-quinolones: Discovery of ligand efficient and dual stage antimalarial lead compounds

Autorzy: Tiago Rodrigues, Ana S. Ressurreição, Filipa P. da Cruz, Inês S. Albuquerque, Jiri Gut, Marta P. Carrasco, Daniel Gonçalves, Rita C. Guedes, Daniel J.V.A. dos Santos, Maria M. Mota, Philip J. Rosenthal, Rui Moreira, Miguel Prudêncio, Francisca Lopes
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Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?

Autorzy: Natasa Terzić, Jelena Konstantinović, Mikloš Tot, Jovana Burojević, Olgica Djurković-Djaković, Jelena Srbljanović, Tijana Štajner, Tatjana Verbić, Mario Zlatović, Marta Machado, Inês S. Albuquerque, Miguel Prudêncio, Richard J. Sciotti, Stevan Pecic, Sarah D’Alessandro, Donatella Taramelli, Bogdan A. Šolaja
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Long-Term Immune Reconstitution of Naive and Memory T Cell Pools after Haploidentical Hematopoietic Stem Cell Transplantation

Autorzy: Rita I. Azevedo, Maria V.D. Soares, Adriana S. Albuquerque, Rita Tendeiro, Rui S. Soares, Miguel Martins, Dário Ligeiro, Rui M.M. Victorino, João F. Lacerda, Ana E. Sousa
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How Many Sputum Culture Results Do We Need To Monitor Multidrug-Resistant-Tuberculosis (MDR-TB) Patients during Treatment?

Autorzy: S. Janssen, X. Padanilam, R. Louw, R. Mahanyele, G. Coetzee, T. Hanscheid, T. Leenstra, M. P. Grobusch
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Wydawca: American Society for Microbiology
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Declining macrolide resistance in Streptococcus pyogenes in Portugal (2007–13) was accompanied by continuous clonal changes

Autorzy: C. Silva-Costa, M. Ramirez, J. Melo-Cristino
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Spartan: A Comprehensive Tool for Understanding Uncertainty in Simulations of Biological Systems

Autorzy: Kieran Alden, Mark Read, Jon Timmis, Paul S. Andrews, Henrique Veiga-Fernandes, Mark Coles
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Development of functionalized nanoparticles for vaccine delivery to dendritic cells: a mechanistic approach

Autorzy: Joana M Silva, Gaëlle Vandermeulen, Vanessa G Oliveira, Sandra N Pinto, Catarina Rodrigues, Ana Salgado, Carlos A Afonso, Ana S Viana, Christine Jérôme, Liana C Silva, Luis Graca, Véronique Préat, Helena F Florindo
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Tumor cell recognition by γδ T lymphocytes

Autorzy: Daniel V. Correia, Antonio C. Lopes, Bruno Silva-Santos
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N-Cinnamoylation of Antimalarial Classics: Effects of Using Acyl Groups Other than Cinnamoyl toward Dual-Stage Antimalarials

Autorzy: Ana Gomes, Marta Machado, Lis Lobo, Fátima Nogueira, Miguel Prudêncio, Cátia Teixeira, Paula Gomes
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Stabilization of Myc through Heterotypic Poly-Ubiquitination by mLANA Is Critical for γ-Herpesvirus Lymphoproliferation

Autorzy: Lénia Rodrigues, Nikita Popov, Kenneth M. Kaye, J. Pedro Simas
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Invasive infections due to Streptococcus pyogenes: seasonal variation of severity and clinical characteristics, Iceland, 1975 to 2012

Autorzy: L B Olafsdottir, H Erlendsdóttir, J Melo-Cristino, D M Weinberger, M Ramirez, K G Kristinsson, M Gottfredsson
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In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model

Autorzy: Joana M. Silva, Eva Zupancic, Gaëlle Vandermeulen, Vanessa G. Oliveira, Ana Salgado, Mafalda Videira, Manuela Gaspar, Luis Graca, Véronique Préat, Helena F. Florindo
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Human Thymocytes Are Functionally Immature and Differentiate into Cytotoxic Type 1 Effector T Cells upon IL-2/IL-15 Signaling

Autorzy: J. C. Ribot, S. T. Ribeiro, D. V. Correia, A. E. Sousa, B. Silva-Santos
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TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

Autorzy: Shoichiro Tsuji, Lucas Stein, Nobuhiko Kamada, Gabriel Nuñez, Richard Bram, Bruce A. Vallance, Ana E. Sousa, Jeffrey L. Platt, Marilia Cascalho
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Sugar activation and glycosylation in Plasmodium

Autorzy: Marta Cova, João A. Rodrigues, Terry K. Smith, Luis Izquierdo
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The Kaposi Sarcoma Herpesvirus Latency-associated Nuclear Antigen DNA Binding Domain Dorsal Positive Electrostatic Patch Facilitates DNA Replication and Episome Persistence

Autorzy: Shijun Li, Min Tan, Franceline Juillard, Rajesh Ponnusamy, Bruno Correia, J. Pedro Simas, Maria A. Carrondo, Colin E. McVey, Kenneth M. Kaye
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The Majority of Adult Pneumococcal Invasive Infections in Portugal Are Still Potentially Vaccine Preventable in Spite of Significant Declines of Serotypes 1 and 5

Autorzy: Andreia N. Horácio, Jorge Diamantino-Miranda, Sandra I. Aguiar, Mário Ramirez, José Melo-Cristino
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IL-9 Expression by Invariant NKT Cells Is Not Imprinted during Thymic Development

Autorzy: M. Monteiro, A. Agua-Doce, C. F. Almeida, D. Fonseca-Pereira, H. Veiga-Fernandes, L. Graca
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Phylogenetic and clonality analysis of Bacillus pumilus isolates uncovered a highly heterogeneous population of different closely related species and clones

Autorzy: Raquel Branquinho, Luís Meirinhos-Soares, João A. Carriço, Manuela Pintado, Luísa V. Peixe
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Changing epidemiology of group B streptococcal infections among adults in Iceland: 1975–2014

Autorzy: E.S. Björnsdóttir, E.R. Martins, H. Erlendsdóttir, G. Haraldsson, J. Melo-Cristino, K.G. Kristinsson, M. Ramirez
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Preserved CD4 T-cell telomere length during long-lasting HIV-2 infection

Autorzy: Rita Tendeiro, Adriana S. Albuquerque, Russell B. Foxall, Rita Cavaleiro, Rui S. Soares, António P. Baptista, Maria V.D. Soares, Perpétua Gomes, Ana E. Sousa
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The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis

Autorzy: Jorge M Santos, Rita N Bárcia, Sandra I Simões, Manuela M Gaspar, Susana Calado, Ana Água-Doce, Sílvia CP Almeida, Joana Almeida, Mariana Filipe, Mariana Teixeira, José P Martins, Luís Graça, Maria EM Cruz, Pedro Cruz, Helder Cruz
Opublikowane w: Journal of Translational Medicine, Numer 11/1, 2013, Strona(/y) 18, ISSN 1479-5876
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iNKT Cells: Innate Lymphocytes with a Diverse Response

Autorzy: Marta Monteiro, Luis Graca
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Superantigen gene complement of Streptococcus pyogenes—relationship with other typing methods and short-term stability

Autorzy: A. Friães, F. R. Pinto, C. Silva-Costa, M. Ramirez, J. Melo-Cristino
Opublikowane w: European Journal of Clinical Microbiology & Infectious Diseases, Numer 32/1, 2013, Strona(/y) 115-125, ISSN 0934-9723
Wydawca: Springer Verlag
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Decreasing incidence and changes in serotype distribution of invasive pneumococcal disease in persons aged under 18 years since introduction of 10-valent and 13-valent conjugate vaccines in Portugal, July 2008 to June 2012

Autorzy: S I Aguiar, M J Brito, A N Horácio, J P Lopes, M Ramirez, J Melo-Cristino
Opublikowane w: Eurosurveillance, Numer 52, 2014, ISSN 1560-7917
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miR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells

Autorzy: Ana Costa, Joana Afonso, Catarina Osório, Ana L Gomes, Francisco Caiado, Joana Valente, Sandra I Aguiar, Francisco Pinto, Mário Ramirez, Sérgio Dias
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Induced IL-17-Producing Invariant NKT Cells Require Activation in Presence of TGF- and IL-1

Autorzy: M. Monteiro, C. F. Almeida, A. Agua-Doce, L. Graca
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Extensive Dissemination of Methicillin-Resistant Staphylococcus aureus (MRSA) between the Hospital and the Community in a Country with a High Prevalence of Nosocomial MRSA

Autorzy: Diana Espadinha, Nuno A. Faria, Maria Miragaia, Luís Marques Lito, José Melo-Cristino, Hermínia de Lencastre
Opublikowane w: PLoS ONE, Numer 8/4, 2013, Strona(/y) e59960, ISSN 1932-6203
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Human iPSC-Derived Hepatocyte-like Cells Support Plasmodium Liver-Stage Infection In Vitro

Autorzy: Shengyong Ng, Robert E. Schwartz, Sandra March, Ani Galstian, Nil Gural, Jing Shan, Mythili Prabhu, Maria M. Mota, Sangeeta N. Bhatia
Opublikowane w: Stem Cell Reports, Numer 4/3, 2015, Strona(/y) 348-359, ISSN 2213-6711
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Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

Autorzy: Christoph S.N. Klose, Melanie Flach, Luisa Möhle, Leif Rogell, Thomas Hoyler, Karolina Ebert, Carola Fabiunke, Dietmar Pfeifer, Veronika Sexl, Diogo Fonseca-Pereira, Rita G. Domingues, Henrique Veiga-Fernandes, Sebastian J. Arnold, Meinrad Busslinger, Ildiko R. Dunay, Yakup Tanriver, Andreas Diefenbach
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Characterization and optimization of the haemozoin-like crystal (HLC) assay to determine Hz inhibiting effects of anti-malarial compounds

Autorzy: Carolina Tempera, Ricardo Franco, Carlos Caro, Vânia André, Peter Eaton, Peter Burke, Thomas Hänscheid
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Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain

Autorzy: Sofia Santos Costa, Cláudia Mourato, Miguel Viveiros, José Melo-Cristino, Leonard Amaral, Isabel Couto
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Molecular Mechanisms of Differentiation of Murine Pro-Inflammatory γδ T Cell Subsets

Autorzy: Karine Serre, Bruno Silva-Santos
Opublikowane w: Frontiers in Immunology, Numer 4, 2013, ISSN 1664-3224
Wydawca: Frontiers Editorial Office
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Consequences of the variability of the CovRS and RopB regulators among Streptococcus pyogenes causing human infections

Autorzy: Ana Friães, Catarina Pato, José Melo-Cristino, Mario Ramirez
Opublikowane w: Scientific Reports, Numer 5, 2015, Strona(/y) 12057, ISSN 2045-2322
Wydawca: Nature Publishing Group
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Chicago 2014 – 30years of γδ T cells

Autorzy: Marc Bonneville, Zheng W. Chen, Julie Déchanet-Merville, Matthias Eberl, Jean Jacques Fournié, Julie M. Jameson, Richard D. Lopez, Massimo Massaia, Bruno Silva-Santos
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Wydawca: Academic Press
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Simple, sensitive and quantitative bioluminescence assay for determination of malaria pre-patent period

Autorzy: Vanessa Zuzarte-Luis, Joana Sales-Dias, Maria M Mota
Opublikowane w: Malaria Journal, Numer 13/1, 2014, Strona(/y) 15, ISSN 1475-2875
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Primaquine–pyrimidine hybrids: Synthesis and dual-stage antiplasmodial activity

Autorzy: Hardeep Kaur, Marta Machado, Carmen de Kock, Peter Smith, Kelly Chibale, Miguel Prudêncio, Kamaljit Singh
Opublikowane w: European Journal of Medicinal Chemistry, Numer 101, 2015, Strona(/y) 266-273, ISSN 0223-5234
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Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

Autorzy: R. S. Paiva, A. C. Lino, M.-L. Bergman, I. Caramalho, A. E. Sousa, S. Zelenay, J. Demengeot
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Delta-like 1-Mediated Notch Signaling Enhances the In Vitro Conversion of Human Memory CD4 T Cells into FOXP3-Expressing Regulatory T Cells

Autorzy: C. Mota, V. Nunes-Silva, A. R. Pires, P. Matoso, R. M. M. Victorino, A. E. Sousa, I. Caramalho
Opublikowane w: The Journal of Immunology, Numer 193/12, 2014, Strona(/y) 5854-5862, ISSN 0022-1767
Wydawca: American Association of Immunologists
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PCR based differentiation between Streptococcus dysgalactiae subsp. equisimilis strains isolated from humans and horses

Autorzy: S. Preziuso, M.D. Pinho, A.R. Attili, J. Melo-Cristino, E. Acke, A.C. Midwinter, V. Cuteri, M. Ramirez
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Point-of-care tests: where is the point?

Autorzy: Thomas Hänscheid, Maria Rebelo, Martin P Grobusch
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Serotype discrimination of encapsulated Streptococcus pneumoniae strains by Fourier-transform infrared spectroscopy and chemometrics

Autorzy: M. Vaz, L. Meirinhos-Soares, C.C.S. Sousa, M. Ramirez, J. Melo-Cristino, J.A. Lopes
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Recruitment of γδ T lymphocytes to tumors

Autorzy: Telma Lança, Bruno Silva-Santos
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Wydawca: Landes Bioscience
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A transcription-independent epigenetic mechanism is associated with antigenic switching in Trypanosoma brucei

Autorzy: Francisco Aresta-Branco, Silvia Pimenta, Luisa M. Figueiredo
Opublikowane w: Nucleic Acids Research, 2015, Strona(/y) gkv1459, ISSN 0305-1048
Wydawca: Oxford University Press
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Reduced BAFF-R and Increased TACI Expression in Common Variable Immunodeficiency

Autorzy: Rita R. Barbosa, Susana L. Silva, Sara P. Silva, Alcinda C. Melo, M. Conceição Pereira-Santos, João T. Barata, Lennart Hammarström, Marília Cascalho, Ana E. Sousa
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Wydawca: Kluwer Academic/Plenum Publishers
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Differentiation and Activation of γδ T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors

Autorzy: Julie C. Ribot, Bruno Silva-Santos
Opublikowane w: Crossroads Between Innate and Adaptive Immunity IV, 2013, Strona(/y) 95-105, ISBN 978-1-4614-6217-0
Wydawca: Springer New York
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