The integration of cell signalling and mechanical forces in vascular morphology

Rezultaty

Update on the data management plan of the project

Publikacje

SFAlab: image-based quantification of mechano-active ventral actin stress fibers in adherent cells

Autorzy: Dylan Mostert, Janine Grolleman, Mark C. van Turnhout, Bart G. W. Groenen, Vito Conte, Cecilia M. Sahlgren, Nicholas A. Kurniawan, Carlijn V. C. Bouten
Opublikowane w: Frontiers in Cell and Developmental Biology, 2023, ISSN 2296-634X
Wydawca: Switzerland
DOI: 10.3389/fcell.2023.1267822

Environmental stiffness restores mechanical homeostasis in vimentin-depleted cells

Autorzy: Janine Grolleman, Nicole C. A. van Engeland, Minahil Raza, Sepinoud Azimi, Vito Conte, Cecilia M. Sahlgren, Carlijn V. C. Bouten
Opublikowane w: Scientific Reports, 2023, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-023-44835-8

Organ-on-a-chip technologies for biomedical research and drug development: A focus on the vasculature

Autorzy: Diosángeles Soto Véliz, Kai-Lan Lin, Cecilia Sahlgren
Opublikowane w: Smart Medicine, 2023, ISSN 2751-1871
Wydawca: Wiley Open Access
DOI: 10.1002/smmd.20220030

Notch signaling regulates strain-mediated phenotypic switching of vascular smooth muscle cells

Autorzy: Cansu Karakaya, Mark C. Van Turnhout, Valery L. Visser, Tommaso Ristori, Carlijn V. C. Bouten, Cecilia M. Sahlgren, Sandra Loerakker
Opublikowane w: Frontiers in Cell and Developmental Biology, 2022, ISSN 2296-634X
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fcell.2022.910503

A multiscale computational model of arterial growth and remodeling including Notch signaling

Autorzy: Jordy G. M. van Asten, Marcos Latorre, Cansu Karakaya, Frank P. T. Baaijens, Cecilia M. Sahlgren, Tommaso Ristori, Jay D. Humphrey, Sandra Loerakker
Opublikowane w: Biomechanics and Modeling in Mechanobiology, 2023, ISSN 1617-7959
Wydawca: Springer Verlag
DOI: 10.1007/s10237-023-01697-3

Mechanical regulation of the Notch signaling pathway

Autorzy: Freddy Suarez Rodriguez, Sami Sanlidag, Cecilia Sahlgren
Opublikowane w: Current Opinion in Cell Biology, 2023, ISSN 0955-0674
Wydawca: Elsevier BV
DOI: 10.1016/j.ceb.2023.102244

Notch in mechanotransduction – from molecular mechanosensitivity to tissue mechanostasis

Autorzy: Oscar M. J. A. Stassen, Tommaso Ristori, Cecilia M. Sahlgren
Opublikowane w: Journal of Cell Science, Numer 133/24, 2020, Strona(/y) jcs250738, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.250738

Ex Vivo Models to Decipher the Molecular Mechanisms of Genetic Notch Cardiovascular Disorders

Autorzy: Tommaso Ristori, Marika Sjöqvist, Cecilia M. Sahlgren
Opublikowane w: Tissue Engineering Part C: Methods, Numer 27/3, 2021, Strona(/y) 167-176, ISSN 1937-3384
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2020.0327

Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension

Autorzy: Jordy G. M. van Asten, Tommaso Ristori, David R. Nolan, Caitríona Lally, Frank P. T. Baaijens, Cecilia M. Sahlgren, Sandra Loerakker
Opublikowane w: Journal of the Mechanical Behavior of Biomedical Materials, 2022, ISSN 1751-6161
Wydawca: Elsevier BV
DOI: 10.1016/j.jmbbm.2022.105325

Decoding the PTM-switchboard of Notch

Autorzy: Daniel Antfolk, Christian Antila, Kati Kemppainen, Sebastian K.-J. Landor, Cecilia Sahlgren
Opublikowane w: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Numer 1866/12, 2019, Strona(/y) 118507, ISSN 0167-4889
Wydawca: Elsevier BV
DOI: 10.1016/j.bbamcr.2019.07.002

From structural resilience to cell specification — Intermediate filaments as regulators of cell fate

Autorzy: Marika Sjöqvist, Daniel Antfolk, Freddy Suarez‐Rodriguez, Cecilia Sahlgren
Opublikowane w: The FASEB Journal, 2020, ISSN 0892-6638
Wydawca: Federation of American Societies for Experimental Biology
DOI: 10.1096/fj.202001627r

Engineering tissue morphogenesis: taking it up a Notch

Autorzy: Laura A. Tiemeijer, Sami Sanlidag, Carlijn V. C. Bouten, Cecilia M. Sahlgren
Opublikowane w: Trends in Biotechnology, Numer 01677799, 2022, ISSN 0167-7799
Wydawca: Elsevier BV
DOI: 10.1016/j.tibtech.2022.01.007

A biomimetic microfluidic model to study signalling between endothelial and vascular smooth muscle cells under hemodynamic conditions

Autorzy: Nicole C. A. van Engeland, Andreas M. A. O. Pollet, Jaap M. J. den Toonder, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren
Opublikowane w: Lab on a Chip, Numer 18/11, 2018, Strona(/y) 1607-1620, ISSN 1473-0197
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c8lc00286j

Shear stress induces expression, intracellular reorganization and enhanced Notch activation potential of Jagged1

Autorzy: R. C. H. Driessen, O. M. J. A. Stassen, M. Sjöqvist, F. Suarez Rodriguez, J. Grolleman, C. V. C. Bouten, C. M. Sahlgren
Opublikowane w: Integrative Biology, Numer 10/11, 2018, Strona(/y) 719-726, ISSN 1757-9694
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c8ib00036k

Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress

Autorzy: Nicole C. A. van Engeland, Freddy Suarez Rodriguez, Adolfo Rivero-Müller, Tommaso Ristori, Camille L. Duran, Oscar M. J. A. Stassen, Daniel Antfolk, Rob C. H. Driessen, Saku Ruohonen, Suvi T. Ruohonen, Salla Nuutinen, Eriika Savontaus, Sandra Loerakker, Kayla J. Bayless, Marika Sjöqvist, Carlijn V. C. Bouten, John E. Eriksson, Cecilia M. Sahlgren
Opublikowane w: Scientific Reports, Numer 9/1, 2019, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-019-48218-w

Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls

Autorzy: Tommaso Ristori, Oscar M. J. A. Stassen, Cecilia M. Sahlgren, Sandra Loerakker
Opublikowane w: International Journal for Numerical Methods in Biomedical Engineering, Numer 36/4, 2020, ISSN 2040-7939
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3323

Computational Characterization of the Dish-In-A-Dish, A High Yield Culture Platform for Endothelial Shear Stress Studies on the Orbital Shaker

Autorzy: Rob Driessen, Feihu Zhao, Sandra Hofmann, Carlijn Bouten, Cecilia Sahlgren, Oscar Stassen
Opublikowane w: Micromachines, Numer 11/6, 2020, Strona(/y) 552, ISSN 2072-666X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi11060552

Computational modeling for cardiovascular tissue engineering: the importance of including cell behavior in growth and remodeling algorithms

Autorzy: Sandra Loerakker, Tommaso Ristori
Opublikowane w: Current Opinion in Biomedical Engineering, Numer 15, 2020, Strona(/y) 1-9, ISSN 2468-4511
Wydawca: Elsevier
DOI: 10.1016/j.cobme.2019.12.007

Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis

Autorzy: Sandra Loerakker, Oscar M. J. A. Stassen, Fleur M. ter Huurne, Marcelo Boareto, Carlijn V. C. Bouten, Cecilia M. Sahlgren
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 115/16, 2018, Strona(/y) E3682-E3691, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1715277115

Shape-Morphing Photoresponsive Hydrogels Reveal Dynamic Topographical Conditioning of Fibroblasts

Autorzy: Maaike Bril, Aref Saberi, Ignasi Jorba, Mark C. van Turnhout, Cecilia M. Sahlgren, Carlijn V.C. Bouten, Albert P.H.J. Schenning, Nicholas A. Kurniawan
Opublikowane w: Advanced Science, 2023, ISSN 2198-3844
Wydawca: Wiley Open Access
DOI: 10.1002/advs.202303136

Mechano-regulated cell–cell signaling in the context of cardiovascular tissue engineering

Autorzy: Cansu Karakaya, Jordy G. M. van Asten, Tommaso Ristori, Cecilia M. Sahlgren, Sandra Loerakker
Opublikowane w: Biomechanics and Modeling in Mechanobiology, 2021, ISSN 1617-7959
Wydawca: Springer Verlag
DOI: 10.1007/s10237-021-01521-w

Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting

Autorzy: Laura A. Timeijer, Tommaso Ristori, Oscar M. J. A. Stassen, Jaakko J. Ahlberg, Jonne J. J. de Bijl, Christopher S. Chen, Katie Bentley, Carlijn V. C. Bouten, Cecilia M. Sahlgren
Opublikowane w: iScience, Numer 25890042, 2022, ISSN 2589-0042
Wydawca: Cell Press / Elsevier
DOI: 10.1016/j.isci.2022.104306

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