Rezultaty Websites, patent fillings, videos etc. (3) Launch of website Brochure and flyer development Development of the project logo/brand Documents, reports (9) Report about the meetings with interest groups from industry ACORN Thematic Workshop ACORN Joint Summer School KPIs definition for ACORN Impact assessment in the 3-year period prior to ACORN for all KPIs Public awareness campaign """Knowledge Transfer Zone"" through meetings between research institutions and enterprises" Knowledge Transfer Zone through meetings between research institutions and enterprises "„The industrial day"" related to nanochemistry applications" The industrial day related to nanochemistry applications Impact assessment by the end of the project and forecast of the following 3-year period Impact assessment by the end of the project and forecast of the following 3year period Publikacje Peer reviewed articles (16) STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer Autorzy: Rômulo S. Cavalcante, Uta Ishikawa, Emanuell S. Silva, Arnóbio A. Silva‐Júnior, Aurigena A. Araújo, Luis J. Cruz, Alan B. Chan, Raimundo F. Araújo Júnior Opublikowane w: British Journal of Pharmacology, 2021, ISSN 0007-1188 Wydawca: Wiley-Blackwell DOI: 10.1111/bph.15373 Effect of Oxaliplatin-Loaded Poly (d,l-Lactide-co-Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug Resistance, and Metastasis Factors of Colorectal Cancer. Autorzy: Ana Luiza C. de S. L. Oliveira; Ana Luiza C. de S. L. Oliveira; Raimundo Fernandes de Araújo Júnior; Raimundo Fernandes de Araújo Júnior; Thaís Gomes de Carvalho; Thaís Gomes de Carvalho; Alan Chan; Timo Schomann; Filippo Tamburini; Lioe-Fee de Geus-Oei; Luis J. Cruz Opublikowane w: Pharmaceutics, Numer 9, 2020, ISSN 1999-4923 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics12020193 Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer. Autorzy: Ana Luiza C. de S. L. Oliveira; Luana Zerillo; Luis J. Cruz; Timo Schomann; Alan Chan; Thaís Gomes de Carvalho; Shirley Vitória de P. Souza; Aurigena Antunes de Araújo; Lioe-Fee de Geus-Oei; Raimundo Fernandes de Araújo Júnior Opublikowane w: MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, Numer 7, 2021, ISSN 0928-4931 Wydawca: Elsevier BV DOI: 10.1016/j.msec.2020.111678 The Effects of Crosslinking on the Rheology and Cellular Behavior of Polymer-Based 3D-Multilayered Scaffolds for Restoring Articular Cartilage Autorzy: Yaima Campos, Francisco J. Sola, Gastón Fuentes, Luis Quintanilla, Amisel Almirall, Luis J. Cruz, José C. Rodríguez-Cabello, Yasuhiko Tabata Opublikowane w: Polymers, Numer 13/6, 2021, Strona(/y) 907, ISSN 2073-4360 Wydawca: MDPI DOI: 10.3390/polym13060907 Dissecting celastrol with machine learning to unveil dark pharmacology Autorzy: Tiago Rodrigues, Bernardo P. de Almeida, Nuno L. Barbosa-Morais, Gonçalo J. L. Bernardes Opublikowane w: Chemical Communications, Numer 55/45, 2019, Strona(/y) 6369-6372, ISSN 1359-7345 Wydawca: Royal Society of Chemistry DOI: 10.1039/c9cc03116b Machine learning for target discovery in drug development Autorzy: Tiago Rodrigues, Gonçalo J.L. Bernardes Opublikowane w: Current Opinion in Chemical Biology, Numer 56, 2020, Strona(/y) 16-22, ISSN 1367-5931 Wydawca: Elsevier BV DOI: 10.1016/j.cbpa.2019.10.003 Computational advances in combating colloidal aggregation in drug discovery Autorzy: Daniel Reker, Gonçalo J. L. Bernardes, Tiago Rodrigues Opublikowane w: Nature Chemistry, Numer 11/5, 2019, Strona(/y) 402-418, ISSN 1755-4330 Wydawca: Nature Publishing Group DOI: 10.1038/s41557-019-0234-9 Thermosensitive hydrogels as sustained drug delivery system for CTLA-4 checkpoint blocking antibodies Autorzy: Chih Kit Chung, Marieke F. Fransen, Koen van der Maaden, Yaima Campos, Jomarien García-Couce, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz Opublikowane w: Journal of Controlled Release, 2020, ISSN 0168-3659 Wydawca: Elsevier BV DOI: 10.1016/j.jconrel.2020.03.050 Doxorubicin Loaded Poloxamer Thermosensitive Hydrogels: Chemical, Pharmacological and Biological Evaluation Autorzy: Chih Kit Chung, Jomarien García-Couce, Yaima Campos, Dana Kralisch, Katja Bierau, Alan Chan, Ferry Ossendorp, Luis Javier Cruz Opublikowane w: Molecules, Numer 25/9, 2020, Strona(/y) 2219, ISSN 1420-3049 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules25092219 Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics Autorzy: Zhenfeng Yu, Christina Eich, Luis J. Cruz Opublikowane w: Frontiers in Chemistry, Numer 8, 2020, ISSN 2296-2646 Wydawca: Frontiers in Chemistry DOI: 10.3389/fchem.2020.00496 Nanocarriers as a Tool for the Treatment of Colorectal Cancer. Autorzy: Ana Luiza C. de S. L. Oliveira; Ana Luiza C. de S. L. Oliveira; Timo Schomann; Lioe-Fee de Geus-Oei; Ellen Kapiteijn; Luis J. Cruz; Raimundo Fernandes de Araújo Júnior Opublikowane w: Pharmaceutics, Numer 9, 2021, ISSN 1999-4923 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics13081321 Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery Autorzy: Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei Opublikowane w: Molecules, Numer 25/5, 2020, Strona(/y) 1181, ISSN 1420-3049 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules25051181 PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells Autorzy: Luis J. Cruz, Thamar van Dijk, Olena Vepris, Tracy M.W.Y. Li, Timo Schomann, Fabio Baldazzi, Ryo Kurita, Yukio Nakamura, Frank Grosveld, Sjaak Philipsen, Christina Eich Opublikowane w: Biomaterials, Numer 268, 2021, Strona(/y) 120580, ISSN 0142-9612 Wydawca: Pergamon Press Ltd. DOI: 10.1016/j.biomaterials.2020.120580 Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues Autorzy: Pablo Lara, Alan B. Chan, Luis J. Cruz, Andrew F. G. Quest, Marcelo J. Kogan Opublikowane w: Pharmaceutics, Numer 12/11, 2020, Strona(/y) 1022, ISSN 1999-4923 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics12111022 Synthesis and Evaluation of AlgNa-g-Poly(QCL-co-HEMA) Hydrogels as Platform for Chondrocyte Proliferation and Controlled Release of Betamethasone Autorzy: Jomarien García-Couce, Marioly Vernhes, Nancy Bada, Lissette Agüero, Oscar Valdés, José Alvarez-Barreto, Gastón Fuentes, Amisel Almirall, Luis J. Cruz Opublikowane w: International Journal of Molecular Sciences, Numer 22/11, 2021, Strona(/y) 5730, ISSN 1422-0067 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22115730 Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties Autorzy: Claudia Morilla, Elianis Perdomo, Ana Karla Hernández, Ramcy Regalado, Amisel Almirall, Gastón Fuentes, Yaima Campos Mora, Timo Schomann, Alan Chan, Luis J. Cruz Opublikowane w: Molecules, Numer 26/11, 2021, Strona(/y) 3272, ISSN 1420-3049 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules26113272 Other (1) Triplet-Triplet Annihilation PLGA-Nanoparticles for Cancer Bioimaging Autorzy: Olena Vepris, Christina Eich, Yansong Feng, Hong Zhang, Eric. L. Kaijzel, Luis J. Cruz Opublikowane w: 2020 Wydawca: Biorxiv DOI: 10.1101/2020.09.02.274969 Prawa własności intelektualnej Patent (1) USE OF CONJUGATES COMPRISING TUMOUR-SELECTIVE LIGANDS AND GROUPS CAPABLE OF RELEASING CARBON MONOXIDE (CO), FOR EXERTING IMMUNOMODULATORY EFFECTS IN CANCER TREATMENT Numer wniosku/publikacji: 20 21058146 Data: 2021-03-29 Wyszukiwanie danych OpenAIRE... Podczas wyszukiwania danych OpenAIRE wystąpił błąd Brak wyników
