Polymer Materials for Cryogenic Storage and Distribution of Biologics

Informacje na temat projektu

ICE_PACK

Identyfikator umowy o grant: 866056

DOI

10.3030/866056

Data podpisania przez KE 3 Lutego 2020

Data rozpoczęcia 1 Września 2020

Data zakończenia 31 Sierpnia 2027

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 999 863,75

Wkład UE

€ 1 999 863,75

Koordynowany przez

THE UNIVERSITY OF MANCHESTER
United Kingdom

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (37)

Post-thaw application of ROCK-inhibitors increases cryopreserved T-cell yield

Autorzy: Natalia Gonzalez-Martinez; Matthew I. Gibson
Opublikowane w: RSC Medicinal Chemistry, Numer 1, 2024, ISSN 2632-8682
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3md00378g

Proline-conditioning and chemically-programmed ice nucleation protects spheroids during cryopreservation

Autorzy: Yanan Gao; Akalabya Bissoyi; Nina L. H. Kinney; Thomas F. Whale; Qiongyu Guo; Matthew I. Gibson
Opublikowane w: ChemComm, Numer 9, 2023, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3cc02252h

Cryopreservation of assay-ready hepatocyte monolayers by chemically-induced ice nucleation: preservation of hepatic function and hepatotoxicity screening capabilities

Autorzy: Ruben M. F. Tomás; Robert Dallman; Thomas R. Congdon; Matthew I. Gibson
Opublikowane w: Biomaterials Science, Numer 2, 2023, ISSN 2047-4849
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3bm01046e

Glycan-Based Flow-Through Device for the Detection of SARS-COV-2

Autorzy: Alexander N. Baker, Sarah-Jane Richards, Sarojini Pandey, Collette S. Guy, Ashfaq Ahmad, Muhammad Hasan, Caroline I. Biggs, Panagiotis G. Georgiou, Alexander J. Zwetsloot, Anne Straube, Simone Dedola, Robert A. Field, Neil R. Anderson, Marc Walker, Dimitris Grammatopoulos, Matthew I. Gibson
Opublikowane w: ACS Sensors, Numer 6/10, 2021, Strona(/y) 3696-3705, ISSN 2379-3694
Wydawca: American Chemical Society
DOI: 10.1021/acssensors.1c01470

Cryopreserved Kidney Epithelial (Vero) Cell Monolayers for Rapid Viral Quantification, Enabled by a Combination of Macromolecular Cryoprotectants

Autorzy: Agnieszka Nagorska, Ruben M. F. Tomás, Afifah Tasnim, Nicole C. Robb, Matthew I. Gibson
Opublikowane w: Biomacromolecules, Numer 25, 2024, Strona(/y) 5352-5358, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.4c00760

Lateral Flow Glyco-Assays for the Rapid and Low-Cost Detection of Lectins–Polymeric Linkers and Particle Engineering Are Essential for Selectivity and Performance

Autorzy: Alexander N. Baker, Asier R. Muguruza, Sarah-Jane Richards, Panagiotis G. Georgiou, Stephen Goetz, Marc Walker, Simone Dedola, Robert A. Field, Matthew I. Gibson
Opublikowane w: Advanced Healthcare Materials, Numer 11, 2022, Strona(/y) 2101784, ISSN 2192-2659
Wydawca: World Scientific
DOI: 10.1002/adhm.202101784

The polymeric glyco-linker controls the signal outputs for plasmonic gold nanorod biosensors due to biocorona formation

Autorzy: Alessia Pancaro, Michal Szymonik, Panagiotis G. Georgiou, Alexander N. Baker, Marc Walker, Peter Adriaensens, Jelle Hendrix, Matthew I. Gibson, Inge Nelissen
Opublikowane w: Nanoscale, Numer 13/24, 2021, Strona(/y) 10837-10848, ISSN 2040-3364
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1nr01548f

Polymer-tethered glycosylated gold nanoparticles recruit sialylated glycoproteins into their protein corona, leading to off-target lectin binding.

Autorzy: Ashfaq Ahmad; Panagiotis G. Georgiou; Alessia Pancaro; Muhammad Hasan; Inge Nelissen; Matthew I. Gibson
Opublikowane w: Nanoscale, Numer 14, 2022, Strona(/y) 13261-13273, ISSN 2040-3372
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2nr01818g

Synthesis of poly(vinyl alcohol) by blue light bismuth oxide photocatalysed RAFT. Evaluation of the impact of freeze/thaw cycling on ice recrystallisation inhibition

Autorzy: Ioanna Kontopoulou; Thomas R. Congdon; Simon Bassett; Ben Mair; Matthew Gibson
Opublikowane w: Polymer Chemistry, 2022, ISSN 1759-9962
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2py00852a

Cryopreservation of Liver-Cell Spheroids with Macromolecular Cryoprotectants.

Autorzy: Akalabya Bissoyi; Ruben M. F. Tomás; Yanan Gao; Qiongyu Guo; Matthew I. Gibson
Opublikowane w: ACS Applied Materials & Interfaces, Numer 15, 2023, Strona(/y) 2630–2638, ISSN 1944-8252
Wydawca: American Chemical Society
DOI: 10.1021/acsami.2c18288

Minimalistic ice recrystallisation inhibitors based on phenylalanine.

Autorzy: Matthew T. Warren; Iain Galpin; Muhammad Hasan; Steven A. Hindmarsh; John D. Padrnos; Charlotte Edwards-Gayle; Robert T. Mathers; Dave J. Adams; Gabriele C. Sosso; Matthew I. Gibson
Opublikowane w: Chemical Communications, 2022, ISSN 1364-548X
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2cc02531k

Ice Recrystallization Inhibition by Amino Acids: The Curious Case of Alpha- and Beta-Alanine

Autorzy: Matthew T. Warren; Iain Galpin; Fabienne Bachtiger; Matthew I. Gibson; Gabriele C. Sosso
Opublikowane w: The Journal of Physical Chemistry Letters, Numer 13, 2022, Strona(/y) 2237-2244, ISSN 1948-7185
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpclett.1c04080

Proline pre-conditioning of Jurkat cells improves recovery after cryopreservation

Autorzy: Alex Murray; Peter Kilbride; Matthew I. Gibson
Opublikowane w: RSC Medicinal Chemistry, Numer 6, 2023, ISSN 2632-8682
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3md00274h

Polymer-Mediated Cryopreservation of Bacteriophages.

Autorzy: Huba L Marton, Kathryn M Styles, Peter Kilbride, Antonia P. Sagona, Matthew I. Gibson
Opublikowane w: Biomacromolecules, Numer 22, 2021, Strona(/y) 5281-5289, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.1c01187

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation

Autorzy: Yanan Gao, Christopher A. Griffiths, Nina L. H. Kinney, Qiongyu Guo, Matthew I. Gibson, and Thomas F. Whale
Opublikowane w: JACS Au, Numer 3, 2023, Strona(/y) 1314-1320, ISSN 2691-3704
Wydawca: American Chemical Society
DOI: 10.1021/jacsau.3c00056

Chemical approaches to cryopreservation

Autorzy: Kathryn A. Murray & Matthew I. Gibson
Opublikowane w: Nature Reviews Chemistry, 2022, ISSN 2397-3358
Wydawca: Spinger-Nature
DOI: 10.1038/s41570-022-00407-4

Synthesis of Poly(2-(methylsulfinyl)ethyl methacrylate) via Oxidation of Poly(2-(methylthio)ethyl methacrylate): Evaluation of the Sulfoxide Side Chain on Cryopreservation

Autorzy: Toru Ishibe; Natalia Gonzalez-Martinez; Panagiotis G. Georgiou; Kathryn A. Murray; Matthew I. Gibson
Opublikowane w: ACS Polymers Au, Numer 2, 2022, Strona(/y) 449-457, ISSN 2694-2453
Wydawca: American Chemical Society
DOI: 10.1021/acspolymersau.2c00028

Data-driven Discovery of Potent Small Molecule Ice Recrystallisation Inhibitors

Autorzy: Matthew T. Warren, Caroline I. Biggs, Akalabya Bissoyi, Matthew I. Gibson, Gabriele C. Sosso
Opublikowane w: Nature Communications, 2023, Strona(/y) 8082, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.26434/chemrxiv-2023-gvvk0

Assay-ready Cryopreserved Cell Monolayers Enabled by Macromolecular Cryoprotectants

Autorzy: Ruben M. F. Tomás, Akalabya Bissoyi, Thomas R. Congdon, and Matthew I. Gibson
Opublikowane w: Biomacromolecules, 2022, ISSN 1526-4602
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.2c00791

High interspecific variability in ice nucleation activity suggests pollen ice nucleators are incidental

Autorzy: Nina L. H. Kinney, Charles A. Hepburn, Matthew I. Gibson, Daniel Ballesteros, Thomas F. Whale
Opublikowane w: Biogeosciences, Numer 21, 2024, Strona(/y) 3201-3214, ISSN 1726-4189
Wydawca: Copernicus GmbH
DOI: 10.5194/bg-21-3201-2024

High Molecular Weight Polyproline as a Potential Biosourced Ice Growth Inhibitor: Synthesis, Ice Recrystallization Inhibition, and Specific Ice Face Binding

Autorzy: Nicola Judge, Panagiotis G. Georgiou, Akalabya Bissoyi, Ashfaq Ahmad, Andreas Heise, and Matthew I. Gibson
Opublikowane w: Biomacromolecules, Numer 24, 2023, Strona(/y) 2459-2468, ISSN 1526-4602
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.2c01487

End-functionalized poly(vinylpyrrolidone) for ligand display in lateral flow device test lines

Autorzy: Alexander N. Baker; Thomas R. Congdon; Sarah-Jane Richards; Panagiotis G. Georgiou; Marc Walker; Simone Dedola; Robert A. Field; Robert A. Field; Matthew I. Gibson
Opublikowane w: Polymers Au, Numer 2, 2021, Strona(/y) 69-79, ISSN 2694-2453
Wydawca: American Chemical Society
DOI: 10.1021/acspolymersau.1c00032

Degradable Polyampholytes from Radical Ring-Opening Copolymerization Enhance Cellular Cryopreservation

Autorzy: Théo Pesenti; Chen Zhu; Natalia Gonzalez-Martinez; Ruben M. F. Tomás; Matthew I. Gibson; Julien Nicolas
Opublikowane w: ACS Macroletters, 2022, ISSN 2161-1653
Wydawca: American Chemical Society
DOI: 10.1021/acsmacrolett.2c00298

Cryopreservation and Rapid Recovery of Differentiated Intestinal Epithelial Barrier Cells at Complex Transwell Interfaces Is Enabled by Chemically Induced Ice Nucleation

Autorzy: Akalabya Bissoyi; Yanan Gao; Ruben M. F. Tomás; Nina L. H. Kinney; Thomas F. Whale; Qiongyu Guo; Matthew I. Gibson
Opublikowane w: ACS Applied Materials and Interfaces, Numer 4, 2024, ISSN 1944-8252
Wydawca: American Chemical Society
DOI: 10.1021/acsami.4c03931

Pollen derived macromolecules serve as a new class of ice-nucleating cryoprotectants

Autorzy: Murray, K.A.; Kinney, N.L.H.; Griffiths, C.A.; Hasan, M.; Gibson, M.I.; Whale, T.F.
Opublikowane w: Scientific Reports, Numer 2, 2022, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-15545-4

Discrimination between protein glycoforms using lectin-functionalised gold nanoparticles as signal enhancers

Autorzy: Marta M. P. S. Neves; Sarah-Jane Richards; Alexander N. Baker; Marc Walker; Panagiotis G. Georgiou; Matthew I. Gibson
Opublikowane w: Nanoscale Horizons, 2023, ISSN 2055-6764
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2nh00470d

Trehalose in cryopreservation. Applications, mechanisms and intracellular delivery opportunities

Autorzy: Alex Murray, Peter Kilbride, Matthew I. Gibson
Opublikowane w: RSC Medicinal Chemistry, Numer 15, 2024, Strona(/y) 2980-2995, ISSN 2632-8682
Wydawca: Royal Society of Chemistry (RSC)
DOI: 10.1039/d4md00174e

Induced Extracellular Ice Nucleation Protects Cocultured Spheroid Interior and Exterior during Cryopreservation

Autorzy: Yanan Gao, Akalabya Bissoyi, Qiongyu Guo, Matthew I. Gibson
Opublikowane w: ACS Biomaterials Science & Engineering, Numer 11, 2025, Strona(/y) 208-212, ISSN 2373-9878
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/acsbiomaterials.4c00958

Poly(vinyl alcohol) Molecular Bottlebrushes Nucleate Ice

Autorzy: Panagiotis G. Georgiou; Nina L. H. Kinney; Ioanna Kontopoulou; Alexander N. Baker; Steven A. Hindmarsh; Akalabya Bissoyi; Thomas R. Congdon; Thomas F. Whale; Matthew I. Gibson
Opublikowane w: Biomacromolecules, Numer 23, 2022, Strona(/y) 5285–5296, ISSN 1526-4602
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.2c01097

Glycosylated gold nanoparticles in point of care diagnostics: from aggregation to lateral flow

Autorzy: Alexander N. Baker; George W. Hawker-Bond; Panagiotis G. Georgiou; Simone Dedola; Robert A. Field; Matthew I. Gibson
Opublikowane w: Chemical Society Reviews, Numer 51, 2022, Strona(/y) 7238-7259, ISSN 1460-4744
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2cs00267a

Mechanical release of homogenous proteins from supramolecular gels

Autorzy: Simona Bianco, Muhammad Hasan, Ashfaq Ahmad, Sarah-Jane Richards, Bart Dietrich, Matthew Wallace, Qiao Tang, Andrew J. Smith, Matthew I. Gibson, Dave J. Adams
Opublikowane w: Nature, Numer 631, 2024, Strona(/y) 544-548, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-024-07580-0

Plasmonic Detection of SARS-CoV-2 Spike Protein with Polymer-Stabilized Glycosylated Gold Nanorods.

Autorzy: Panagiotis G. Georgiou; Collette S. Guy; Muhammad Hasan; Ashfaq Ahmad; Sarah-Jane Richards; Alexander N. Baker; Neer V. Thakkar; Marc Walker; Sarojini Pandey; Neil R. Anderson; Dimitris Grammatopoulos; Matthew I. Gibson
Opublikowane w: ACS MacroLetters, 2022, ISSN 2161-1653
Wydawca: American Chemical Society
DOI: 10.1021/acsmacrolett.1c00716

Anionic Synthetic Polymers Prevent Bacteriophage Infection

Autorzy: Huba L. Marton, Peter Kilbride, Ashfaq Ahmad, Antonia P. Sagona, and Matthew I. Gibson
Opublikowane w: Journal of the American Chemical Society, Numer 145, 2023, Strona(/y) 8794-8799, ISSN 1520-5126
Wydawca: American Chemical Society
DOI: 10.1021/jacs.3c01874

Polymer-tethered glyconanoparticle colourimetric biosensors for lectin binding: structural and experimental parameters to ensure a robust output

Autorzy: Julian Micallef; Alexander N. Baker; Sarah-Jane Richards; Douglas E. Soutar; Panagiotis G. Georgiou; Marc Walker; Matthew I. Gibson
Opublikowane w: RSC Advances, 2022, ISSN 2046-2069
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2ra06265h

Polymer Self-Assembly Induced Enhancement of Ice Recrystallization Inhibition

Autorzy: Panagiotis G. Georgiou, Huba L. Marton, Alexander N. Baker, Thomas R. Congdon, Thomas F. Whale, Matthew I. Gibson
Opublikowane w: Journal of the American Chemical Society, Numer 143/19, 2021, Strona(/y) 7449-7461, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.1c01963

Screening of Hydrophilic Polymers Reveals Broad Activity in Protecting Phages during Cryopreservation

Autorzy: Huba L. Marton; Apoorva Bhatt; Antonia P. Sagona; Peter Kilbride; Matthew I. Gibson
Opublikowane w: Biomacromolecules, Numer 3, 2023, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.3c01042

Red Blood Cell Cryopreservation with Minimal Post-Thaw Lysis Enabled by a Synergistic Combination of a Cryoprotecting Polyampholyte with DMSO/Trehalose

Autorzy: Alex Murray, Thomas R. Congdon, Ruben M. F. Tomás, Peter Kilbride, Matthew I. Gibson
Opublikowane w: Biomacromolecules, 2021, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.1c00599