Infinite Protein Self-Assembly in Health and Disease

Publikacje

Protein Abundance Biases the Amino Acid Composition of Disordered Regions to Minimize Non-functional Interactions

Autorzy: Benjamin Dubreuil, Or Matalon, Emmanuel D. Levy
Opublikowane w: Journal of Molecular Biology, Numer 431/24, 2019, Strona(/y) 4978-4992, ISSN 0022-2836
Wydawca: Academic Press
DOI: 10.1016/j.jmb.2019.08.008

Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules in S. cerevisiae.

Autorzy: Mang Zhu; Erich R. Kuechler; Joyce Zhang; Or Matalon; Benjamin Dubreuil; Analise Hofmann; Christopher J. R. Loewen; Emmanuel D. Levy; Joerg Gsponer; Thibault Mayor
Opublikowane w: Journal of Cell Science, Numer 1, 2020, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.244657

Designer protein assemblies with tunable phase diagrams in living cells

Autorzy: Meta Heidenreich, Joseph M. Georgeson, Emanuele Locatelli, Lorenzo Rovigatti, Saroj Kumar Nandi, Avital Steinberg, Yotam Nadav, Eyal Shimoni, Samuel A. Safran, Jonathan P. K. Doye, Emmanuel D. Levy
Opublikowane w: Nature Chemical Biology, 2020, ISSN 1552-4450
Wydawca: Nature Publishing Group
DOI: 10.1038/s41589-020-0576-z

<scp>CC<sup>+</sup></scp>: A searchable database of validated coiled coils in <scp>PDB</scp> structures and <scp>AlphaFold2</scp> models

Autorzy: Prasun Kumar; Rokas Petrenas; William M. Dawson; Hugo Schweke; Emmanuel D. Levy; Derek N. Woolfson
Opublikowane w: Crossref, Numer 5, 2023, ISSN 0961-8368
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1002/pro.4789

Discriminating physiological from non‐physiological interfaces in structures of protein complexes: A community‐wide study

Autorzy: Hugo Schweke; Qifang Xu; Gerardo Tauriello; Lorenzo Pantolini; Torsten Schwede; Frédéric Cazals; Alix Lhéritier; Juan Fernandez‐Recio; Luis Angel Rodríguez‐Lumbreras; Ora Schueler‐Furman; Julia K. Varga; Brian Jiménez‐García; Manon F. Réau; Alexandre M. J. J. Bonvin; Castrense Savojardo; Pier‐Luigi Martelli; Rita Casadio; Jérôme Tubiana; Haim J. Wolfson; Romina Oliva; Didier Bar
Opublikowane w: Crossref, Numer 5, 2023, ISSN 1615-9853
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.202200323

Molecular and environmental determinants of biomolecular condensate formation

Autorzy: José A. Villegas, Meta Heidenreich, Emmanuel D. Levy
Opublikowane w: Nature Chem. Bio., 2022, ISSN 1552-4450
Wydawca: Nature Publishing Group
DOI: 10.1038/s41589-022-01175-4

PDB-wide identification of physiological hetero-oligomeric assemblies based on conserved quaternary structure geometry

Autorzy: Sucharita Dey, Emmanuel D. Levy
Opublikowane w: Structure, Numer 29/11, 2021, Strona(/y) 1303-1311.e3, ISSN 0969-2126
Wydawca: Cell Press
DOI: 10.1016/j.str.2021.07.012

Affinity and Valence Impact the Extent and Symmetry of Phase Separation of Multivalent Proteins

Autorzy: Saroj Kumar Nandi; Daniel Österle; Meta Heidenreich; Emmanuel D. Levy; Samuel A. Safran
Opublikowane w: Crossref, Numer 2, 2022, ISSN 0031-9007
Wydawca: American Physical Society
DOI: 10.1103/physrevlett.129.128102

PDBe-KB: collaboratively defining the biological context of structural data

Autorzy: Mihaly Varadi; Stephen Anyango; David R. Armstrong; John M. Berrisford; Preeti Choudhary; Mandar Deshpande; Nurul Nadzirin; Sreenath Nair; Lukáš Pravda; Ahsan Tanweer; Bissan Al-Lazikani; Claudia Andreini; Geoffrey J. Barton; David Bednar; Karel Berka; Tom L. Blundell; Kelly P Brock; José María Carazo; Jiri Damborsky; Alessia David; Sucharita Dey; Roland L. Dunbrack; Juan Fernandez Recio; Fran
Opublikowane w: D534-D542, Numer 2, 2021, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkab988

A unified statistical potential reveals that amino acid stickiness governs nonspecific recruitment of client proteins into condensates

Autorzy: José A. Villegas; Emmanuel D. Levy
Opublikowane w: Crossref, Numer 1, 2022, ISSN 0961-8368
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1002/pro.4361

Abundance Imparts Evolutionary Constraints of Similar Magnitude on the Buried, Surface, and Disordered Regions of Proteins

Autorzy: Benjamin Dubreuil, Emmanuel D. Levy
Opublikowane w: Frontiers in Molecular Biosciences, Numer 8, 2021, ISSN 2296-889X
Wydawca: Frontiers
DOI: 10.3389/fmolb.2021.626729

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